KONFLUENT VE RETİKÜLER PAPİLLOMAZTOZİSLİ İKİ OLGU SUNUMU Two Case Reports With Confluent and Reticulated Papillomatosis

Yıl 2019, Cilt: 9 Sayı: 3, 157 - 160, 16.09.2019

Gülhan Gürel , Sevinç Şahin Emine Çölgeçen

Öz

ÖZET

Konfluent ve retiküler papillomatozis, 1927 yılında Gougerot ve Carteaud tarafından ilk kez tanımlanmıştır. Nadir

görülen bu hastalık daha çok adolesanları etkileyen, birleşmeye eğilimli retiküler paternde hiperkeratotik

lezyonlarla karakterizedir. Patofizyolojisi halen net olarak bilinmemektedir, tedaviye dirençlidir ve rekürrensler

sık görülmektedir. Pitriyazis versikolor, akantozis nigrikans, prurigo pigmentosa, Darier hastalığı, epidermal

nevüs, kutanöz amiloidoz, Dowling-Degos hastalığı, iktiyozis, seboreik dermatit ve parapsoriazis gibi hastalıklar

da ayırıcı tanıda akla gelmelidir. KRP’nin tedavisi oldukça zordur. Tedavi seçenekleri arasında topikal ve sistemik

retinoidler, topikal kalsipotriol, topikal 5 fluorourasil, topikal antifungaller, mupirosin, topikal takrolimus, oral

amoksisilin, eritromisin, azitromisin, minosiklin, fototerapi ve dermabrazyon yer almaktadır. Burada 14 yaşında

ve 25 yaşında konfluent ve retiküler papillomatozis tanısı konulan iki kadın olgu sunulmaktadır.

Anahtar kelimeler: İsotretinoin; Konfluent ve retiküler papillomatozis; Pitriyazis versikolor

ABSTRACT

Confluent and reticulated papillomatosis was first described in 1927 by Gougerot and Carteaud. It is a rare

disease that predominantly affects adolescents and is characterized by hyperkeratotic lesions that coalesce

into a reticulated pattern. Pathophysiology is still unclear, treatment is resistant and recurrences are common.

Diseases such as pityriasis versicolor, acanthosis nigricans, prurigo pigmentosa, Darier's disease, epidermal

nevus, cutaneous amyloidosis, Dowling-Degos disease, ichthyosis, seborrheic dermatitis and parapsoriasis

should be considered in the differential diagnosis. Treatment of confluent and reticulated papillomatosis is

very difficult. Treatment options of confluent and reticulated papillomatosis included topical and systemic

retinoids, topical calcipotriol, topical 5 fluorouracil, topical antifungals, mupirocin, topical tacrolimus, oral

amoxicillin, erythromycin, azithromycin, minocycline, phototherapy and dermabrasion . Here we present two

cases of 14-year-old and 25-year-old female diagnosed as confluent and reticular papillomatosis.

Keywords: Isotretinoin; Confluent and reticular papillomatosis; Pityriasis versicolor

Anahtar Kelimeler

KONFLUENT VE RETİKÜLER PAPİLLOMAZTOZİSLİ İKİ OLGU SUNUMU Two Case Reports With Confluent and Reticulated Papillomatosis

Kaynakça

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