PLATELET RICH PLASMA RESULTS IN THE TREATMENT OF FEMUR HEAD AVASCULAR NECROSIS Femur Başı Avasküler Nekroz Tedavisinde Trombosit Zengin Plazma Sonuçları

Yıl 2024, Cilt: 14 Sayı: 3, 135 - 143, 15.09.2024

Hacı Ali Olçar , Murat Korkmaz , Serhat Durusoy , Enes Erdi Kapukaya , Osman Muhammed Özbay , Göker Yurdakul , Satuk Buğrahan Yinanç , Burak Çakar

Öz

ABSTRACT
Objective: It has been observed that the number of patients with hip avascular necrosis who applied to
our clinic after Covid-19 and steroid treatment in Covid-19 treatment has increased. It is emphasized in
the literature that core decompression therapy is effective in early stage femoral head avascular necrosis.
Core it has been emphasized in many publications that the results of intraoperative platelet- rich plasma
(PRP) application after decompression are effective. However, intraoperative the method of application of
platelet- rich plasma (PRP) and its effectiveness in the post-Covid-19 period are not emphasized enough in
the literature. The aim of this study is to evaluate the effect of local platelet-rich plasma (PRP) administered
using the new technique after core decompression to patients diagnosed with avascular necrosis.
Material and Methods: Local platelet- rich plasma (PRP) was applied to 15 hips diagnosed with femoral
head avascular necrosis after core decompression with a new technique. Early results of the patients were
evaluated with Ficat and Harris hip scores.
Results: An improvement was detected in the early clinical and Magnetic resonance (MR) findings of a total
of 15 hip avascular necrosis patients. Local treatment in patients with avascular necrosis with a medical
history of Covid-19 the feasibility of PRP was demonstrated.
Conclusion: This study shows the importance of the intraoperative application method of platelet- rich
plasma (PRP) and that platelet- rich plasma (PRP) can also be applied to Covid-19 patients. But we believe
long-term results are needed.

Anahtar Kelimeler

PLATELET RICH PLASMA RESULTS IN THE TREATMENT, OF FEMUR HEAD AVASCULAR NECROSIS, Femur Başı Avasküler Nekroz Tedavisinde Trombosit Zengin Plazma Sonuçları

Kaynakça

• 1. Assad SK, Sabah M, Kakamad FH, Salih AM, Salih RQ, Mohammed SH, et al. Avascular necrosis of femoral head following COVID-19 infection. Ann Med Surg (Lond) 2023; 85:4206-10.
• 2. Sarma P, Bhattacharyya A, Kaur H, Prajapat M, Prakash A, Kumar S, et al. Efficacy and safety of steroid therapy in COVID-19: A rapid systematic review and Meta-analysis. Indian J Pharmacol 2020; 52:535-50.
• 3. Anderson PA, Jeray KJ, Lane JM, Binkley NC. Bone health optimization: beyond own the bone: AOA critical issues. JBJS 2019; 101:1413-9.
• 4. Gaddini GW, Grant KA, Woodall A, Stull C, Maddalozzo GF, Zhang B, et al. Twelve months of voluntary heavy alcohol consumption in male rhesus macaques suppresses intracortical bone remodeling. Bone 2015; 71:227-36.
• 5. Tan G, Kang PD, Pei FX. Glucocorticoids affect the metabolism of bone marrow stromal cells and lead to osteonecrosis of the femoral head: a review. Chin Med J (Engl) 2012; 125:134-9.
• 6. Özdemir H, Baloğlu M. Femur başının avasküler nekrozu: Tanı ve tedavisi. Türk Ortopedi ve Travmatoloji Birliği Derneği Dergisi 2010; 9:41-51.
• 7. Kahler-Quesada AM, Grant KA, Walter NAR, Newman N, Allen MR, Burr DB, et al. Voluntary Chronic Heavy Alcohol Consumption in Male Rhesus Macaques Suppresses Cancellous Bone Formation and Increases Bone Marrow Adiposity. Alcohol Clin Exp Res 2019; 43:2494-503.
• 8. Weinstein RS. Clinical practice. Glucocorticoid-induced bone disease. N Engl J Med 2011; 365:62-70.
• 9. Zhang YZ, Cao XY, Li XC, Chen J, Zhao YY, Tian Z, et al. Accuracy of MRI diagnosis of early osteonecrosis of the femoral head: a meta-analysis and systematic review. J Orthop Surg Res 2018; 13:167.
• 10. Stöve J, Riederle F, Kessler S, Puhl W, Günther KP. [Reproducibility of radiological classification criteria of femur head necrosis]. Z Orthop Ihre Grenzgeb 2001; 139:163-7.