Türkiyede Yetişen Phedimus stoloniferus Türünün Uçucu Kimyasal Bileşimi ve Biyoaktivite Değerlendirilmesi

Yıl 2019, , 585 - 593, 26.12.2019

Nuri Yıldırım

https://doi.org/10.35193/bseufbd.633654

Öz

Bu
araştırmada, Türkiye'de yetişen Phedimus stoloniferus'un (Crassulaceae)
esansiyel yağında (EO), SPME ve n-hekzan özütünün SPME'sindeki uçucu organik
bileşiklerin (VOC) GC-FID/MS ile analiz edilmiştir. P. stoloniferus'un
EO'daki uçucu bileşiklerin ana kimyasal sınıfını karboksilik asitler oluşturur
(%50.2).  P. stoloniferus'un SPME
ve heksan özütlerinin ve SPME’leri, ana bileşenlerinin aromatik bileşikler
(sırasıyla %51.9 ve %65.9) olduğunu gösterdi. 
P. stoloniferus'tan elde edilen EO, SPME ve  heksan özütlerinin SPME'sindeki  ana bileşikler sırasıyla n-Heksadekanoik asit
(%34.0), 1-metil-4-etilbenzen (%20.2) ve mesitilen (%28.8)’dir. P. stoloniferus'dan
elde edilen esansiyel yağlarda ve çözücü (n-heksan, metanol ve su) özütlerinde
antioksidan ve tirozinaz inhibisyonları da incelenmiştir. P. stoloniferus'un
metanol özütünde antioksidan aktivite en yüksek olarak (TEAC: 1.23± 0.04)
tespit edilmişken, en yüksek tirosinaz enzimi inhibisyonu ise sulu özütte (IC₅₀:
0.168 ± 0.018) gözlendi.

Anahtar Kelimeler

Crassulaceae, Phedimus stoloniferus, SPME, GC-FID/MS, Antioksidan, Tirozinaz İnhibisyonu

Bioactivity Evaluation and Volatile Chemical Composition of Phedimus stoloniferus Species Grown in Turkey

Öz

In this research, volatile organic compounds (VOCs)
in the essential oil (EO), SPME and SPME of n-hexane extract of Phedimus
stoloniferus (Crassulaceae) grown in Turkey were determined by GC-FID/MS.
Major chemical class for the volatile compounds in the EO of P. stoloniferus
is carboxylic acids (50.2%). SPME and SPME of the hexane extracts of P.
stoloniferus revealed aromatic compounds (51.9% and 65.9%, respectively) as
the main constituents. n-Hexadecanoic acid (34.0%), 1-methyl-4-ethylbenzene
(20.2%), and mesitylene (28.8%) were the major compounds in the EO, SPME and
SPME of hexane extract obtained from P. stoloniferus, respectively.  Antioxidant and tyrosinase inhibitions of the
essential oil and n-hexane, methanol, and water extracts obtained from P.
stoloniferus were also studied. While the antioxidant activity was
determined to be highest in methanol extract (TEAC: 1.23±0.04), tyrosinase
enzyme inhibition was highest in the aqueous extract (IC₅₀:
0.168±0.018) of P. stoloniferus.

Anahtar Kelimeler

Crassulaceae, Phedimus stoloniferus, SPME, GC-FID/MS, Antioxidant, Tyrosinase Inhibition

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