Araştırma Makalesi

Droplet-based Microfluidic Device for the Synthesis of Silica Nanoparticles

Cilt: 16 Sayı: 3 29 Eylül 2020
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Droplet-based Microfluidic Device for the Synthesis of Silica Nanoparticles

Öz

Microfluidic reactors are advantageous for nanomaterial synthesis due to their capability to provide controlled reaction environment. In this work, a droplet based microfluidic reactor is designed for the synthesis of silica nanoparticles. The synthesis is carried out in a very controlled environment and a uniform size and shape distribution is achieved. The classical synthesis protocol for silica nanoparticles is modified to use nonpolar solvents in the reaction so that this platform can later be used for coating hydrophobic nanomaterials. Therefore, this study not only presents a new device but also a new synthesis method. The results are compared with conventional batch wise synthesis methods and the obtained nanoparticles showed better size distribution.

Anahtar Kelimeler

Destekleyen Kurum

TÜBİTAK

Proje Numarası

114C092

Teşekkür

E. Y. Erdem would like to acknowledge the Tübitak 2232 grant that founded this research. She also thanks Mr. Alican Özkan and Mr. Arsalan Nikdoost for their help in laboratory studies.

Kaynakça

  1. 1. He, Q, Shi, J. 2010. Mesoporous silica nanoparticle based nano drug delivery systems: synthesis, controlled drug release and delivery, pharmacokinetics and biocompatibility. Journal of Materials Chemistry; 21: 5845-5855.
  2. 2. Zhao, CX, He, L, Qiao, SZ, Middelberg, APJ. 2011. Nanoparticle synthesis in microreactors. Chemical Engineering Science; 66(7): 1463-1479.
  3. 3. Wu, KCW, Yamauchi, Y. 2012. Controlling physical features of mesoporoussilica nanoparticles (MSNs) for emergingapplications. Journal of Materials Chemistry; 22:1251-1256.
  4. 4. Mebert, AM, Baglole, CJ, Desimone, MF, Maysinger, Dusica. 2017. Nanoengineered silica: properties, applications and toxicity. Food and Chemical Toxicology; 109(1): 753-770.
  5. 5. Erdem, EY, Cheng, JC, Doyle, FM, Pisano, AP. 2014. Multitemperature zone, droplet-based microreactor for increased temperature control in nanoparticle synthesis. Small; 10(6): 1076-1080.
  6. 6. Phillips, TW, Lignos, IG, Maceiczyk, RM, DeMello, AJ, DeMello, A. 2014. Nanocrystal synthesis in microfluidic reactors: where next?. Lab Chip.; 14(17): 3172-3180,
  7. 7. Chang, CH, Paul, BK, Remcho, VT, Atre, S, Hutchison, JE. 2008. Synthesis and post-processing of nanomaterials using microreaction technology. Journal of Nanoparticle Research; 10: 965-980.
  8. 8. Nightingale, AM, deMello, JC. 2012. Segmented flow reactors for nanocrystal synthesis. Advanced Materials; 25(13): 1813-1821.

Ayrıntılar

Birincil Dil

İngilizce

Konular

Mühendislik

Bölüm

Araştırma Makalesi

Yayımlanma Tarihi

29 Eylül 2020

Gönderilme Tarihi

29 Nisan 2020

Kabul Tarihi

7 Eylül 2020

Yayımlandığı Sayı

Yıl 2020 Cilt: 16 Sayı: 3

Kaynak Göster

APA
Erdem, E. Y. (2020). Droplet-based Microfluidic Device for the Synthesis of Silica Nanoparticles. Celal Bayar University Journal of Science, 16(3), 245-249. https://doi.org/10.18466/cbayarfbe.729586
AMA
1.Erdem EY. Droplet-based Microfluidic Device for the Synthesis of Silica Nanoparticles. Celal Bayar University Journal of Science. 2020;16(3):245-249. doi:10.18466/cbayarfbe.729586
Chicago
Erdem, Emine Yegan. 2020. “Droplet-based Microfluidic Device for the Synthesis of Silica Nanoparticles”. Celal Bayar University Journal of Science 16 (3): 245-49. https://doi.org/10.18466/cbayarfbe.729586.
EndNote
Erdem EY (01 Eylül 2020) Droplet-based Microfluidic Device for the Synthesis of Silica Nanoparticles. Celal Bayar University Journal of Science 16 3 245–249.
IEEE
[1]E. Y. Erdem, “Droplet-based Microfluidic Device for the Synthesis of Silica Nanoparticles”, Celal Bayar University Journal of Science, c. 16, sy 3, ss. 245–249, Eyl. 2020, doi: 10.18466/cbayarfbe.729586.
ISNAD
Erdem, Emine Yegan. “Droplet-based Microfluidic Device for the Synthesis of Silica Nanoparticles”. Celal Bayar University Journal of Science 16/3 (01 Eylül 2020): 245-249. https://doi.org/10.18466/cbayarfbe.729586.
JAMA
1.Erdem EY. Droplet-based Microfluidic Device for the Synthesis of Silica Nanoparticles. Celal Bayar University Journal of Science. 2020;16:245–249.
MLA
Erdem, Emine Yegan. “Droplet-based Microfluidic Device for the Synthesis of Silica Nanoparticles”. Celal Bayar University Journal of Science, c. 16, sy 3, Eylül 2020, ss. 245-9, doi:10.18466/cbayarfbe.729586.
Vancouver
1.Emine Yegan Erdem. Droplet-based Microfluidic Device for the Synthesis of Silica Nanoparticles. Celal Bayar University Journal of Science. 01 Eylül 2020;16(3):245-9. doi:10.18466/cbayarfbe.729586