Melatoninin Kanser Gelişiminde ve Tedavisinde Antioksidan Rolü

Öz

Dünya çapında ölüm oranları yüksek multifaktoriyel bir hastalık olan kanser, üzerine en çok araştırma yapılan, günümüzde gelişmiş teknolojilere rağmen kesin çözümünü bulamadığımız insanlığı etkileyen hastalıklardan biridir. Antioksidan yönüyle öne çıkan melatonin, hala tam olarak anlaşılamamış birçok mekanizma ve yolakta görev almaktadır. Bu durum çok yönlü bir bileşik olan melatoninin, günümüz dünyasının en büyük sağlık sorunlarından biri olan kanser üzerindeki etkilerine yoğunlaşılmasını sağladı. Geçtiğimiz yarım asır boyunca Melatonin- Kanser ilişkisini aydınlatmaya yönelik birçok araştırma yapılmıştır. Derlenen verilerin büyük bir çoğunluğu, melatoninin kanser gelişimini aşağı yönlü etkilediği ve potansiyel bir tedavi yolu oluşturabileceğini desteklemektedir.

Anahtar Kelimeler

• Melatonin
• Kanser
• Antioksidan
• Oksidatif Stres

Antioxidant Role of Melatonin in The Progression and Treatment of Cancer

Öz

Cancer; It is a multifactorial disease with high fatality. Cancer, which we cannot find a definitive solution to even with our advanced technology in the 21st century, is one of the medical field's most extensively studied topic at current. Melatonin, which stands out with its antioxidant properties, plays a role in many mechanisms and pathways that are still not fully understood. This led to focus on the effects of melatonin, a versatile compound, on cancer, one of the biggest health problems in today's world. Over the past half century, several studies have been carried out to clarify the connection between melatonin and cancer. The majority of the compiled data supports that melatonin has a downward effect on cancer development and may constitute a potential treatment.

Anahtar Kelimeler

• Melatonin
• Cancer
• Antioxidant
• Oxidative Stress

Kaynakça

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