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Vertebral Hemangiomas Mimicking Metastases on Gallium-68 DOTATATE PET/CT: A Case of Gastric Neuroendocrine Tumor

Cilt: 6 Sayı: 1 29 Nisan 2026
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Vertebral Hemangiomas Mimicking Metastases on Gallium-68 DOTATATE PET/CT: A Case of Gastric Neuroendocrine Tumor

Öz

While the diagnostic efficacy of Ga-68 DOTATATE PET/CT for staging neuroendocrine tumors is well established, radiotracer accumulation in benign tissues may lead to false-positive findings and potential diagnostic pitfalls. Vertebral hemangiomas represent a rare but clinically important cause of such false-positive uptake. We report a 77-year-old male with a gastric neuroendocrine tumor who showed focal Ga-68 DOTATATE uptake in the cervical and thoracic vertebrae. Correlation with prior computed tomography (CT) demonstrated that these lesions were benign vertebral hemangiomas, indicating false-positive uptake. This case underscores the importance of correlating PET/CT findings with morphological imaging and considering vertebral hemangiomas in the differential diagnosis of bone uptake on Ga-68 DOTATATE PET/CT.

Anahtar Kelimeler

Destekleyen Kurum

yok

Etik Beyan

ekte

Teşekkür

yok

Kaynakça

  1. Ambrosini V., Nanni C., Fanti S. The use of gallium-68 labeled somatostatin receptors in PET/CT imaging. PET Clin 2014; 9:323-9. Doi: 10.1016/j.cpet.2014.03.008.
  2. Hope TA., Bergsland EK., Bozkurt MF., et al. Appropriate use criteria for somatostatin receptor PET imaging in neuroendocrine tumors. J Nucl Med. 2018; 59:66-74. Doi: 10.2967/jnumed.117.202275.
  3. Kayani I., Bomanji JB., Groves A., et al. Functional imaging of neuroendocrine tumors with combined PET/CT using 68Ga-DOTATATE and 18F-FDG. Cancer 2008; 112:2447-55. Doi: 10.1002/cncr.23469.
  4. Hofman MS., Hicks RJ. Changing paradigms with molecular imaging of neuroendocrine tumors. Discov Med 2012; 14:71-81.
  5. Klinaki I., Al-Nahhas A., Soneji N., Win Z. 68Ga DOTATATE PET/CT uptake in spinal lesions and MRI correlation on a patient with neuroendocrine tumor: potential pitfalls. Clin Nucl Med 2013;38:e449–53.
  6. Saidi B., Fallahi B., Manafi-Farid R., et al. 68Ga-DOTATATE uptake in an intraosseous hemangioma simulating tumoral involvement. Clin Nucl Med 2022; 47:e274-5. Doi: 10.1097/RLU.0000000000004045.
  7. Vertenten B., Goethals L., De Geeter F. 68Ga-DOTATATE uptake in hemangioma simulating metastasis on PET imaging. J Belg Soc Radiol 2019;103:38. Doi: 10.5334/jbsr.1772.
  8. Skoura E., Alshammari A., Syed R., et al. Adolescent with 68Ga-DOTATATE-avid vertebral hemangioma mimicking metastasis. Clin Nucl Med 2015; 40:e378-9. Doi: 10.1097/RLU.0000000000000779.

Ayrıntılar

Birincil Dil

İngilizce

Konular

Nükleer Tıp

Bölüm

Olgu Sunumu

Yayımlanma Tarihi

29 Nisan 2026

Gönderilme Tarihi

24 Ocak 2026

Kabul Tarihi

30 Mart 2026

Yayımlandığı Sayı

Yıl 2026 Cilt: 6 Sayı: 1

Kaynak Göster

APA
Ağartıoğlu, A. İ., Küçüker, K. A., Aksu, A., Atay, A., & Turgut, B. (2026). Vertebral Hemangiomas Mimicking Metastases on Gallium-68 DOTATATE PET/CT: A Case of Gastric Neuroendocrine Tumor. Güncel Tıbbi Araştırmaları Dergisi, 6(1), 13-18. https://doi.org/10.52818/cjmr.1870942
AMA
1.Ağartıoğlu Aİ, Küçüker KA, Aksu A, Atay A, Turgut B. Vertebral Hemangiomas Mimicking Metastases on Gallium-68 DOTATATE PET/CT: A Case of Gastric Neuroendocrine Tumor. GÜTAD. 2026;6(1):13-18. doi:10.52818/cjmr.1870942
Chicago
Ağartıoğlu, Amine İrem, Kadir Alper Küçüker, Ayşegül Aksu, Arif Atay, ve Bulent Turgut. 2026. “Vertebral Hemangiomas Mimicking Metastases on Gallium-68 DOTATATE PET/CT: A Case of Gastric Neuroendocrine Tumor”. Güncel Tıbbi Araştırmaları Dergisi 6 (1): 13-18. https://doi.org/10.52818/cjmr.1870942.
EndNote
Ağartıoğlu Aİ, Küçüker KA, Aksu A, Atay A, Turgut B (01 Nisan 2026) Vertebral Hemangiomas Mimicking Metastases on Gallium-68 DOTATATE PET/CT: A Case of Gastric Neuroendocrine Tumor. Güncel Tıbbi Araştırmaları Dergisi 6 1 13–18.
IEEE
[1]A. İ. Ağartıoğlu, K. A. Küçüker, A. Aksu, A. Atay, ve B. Turgut, “Vertebral Hemangiomas Mimicking Metastases on Gallium-68 DOTATATE PET/CT: A Case of Gastric Neuroendocrine Tumor”, GÜTAD, c. 6, sy 1, ss. 13–18, Nis. 2026, doi: 10.52818/cjmr.1870942.
ISNAD
Ağartıoğlu, Amine İrem - Küçüker, Kadir Alper - Aksu, Ayşegül - Atay, Arif - Turgut, Bulent. “Vertebral Hemangiomas Mimicking Metastases on Gallium-68 DOTATATE PET/CT: A Case of Gastric Neuroendocrine Tumor”. Güncel Tıbbi Araştırmaları Dergisi 6/1 (01 Nisan 2026): 13-18. https://doi.org/10.52818/cjmr.1870942.
JAMA
1.Ağartıoğlu Aİ, Küçüker KA, Aksu A, Atay A, Turgut B. Vertebral Hemangiomas Mimicking Metastases on Gallium-68 DOTATATE PET/CT: A Case of Gastric Neuroendocrine Tumor. GÜTAD. 2026;6:13–18.
MLA
Ağartıoğlu, Amine İrem, vd. “Vertebral Hemangiomas Mimicking Metastases on Gallium-68 DOTATATE PET/CT: A Case of Gastric Neuroendocrine Tumor”. Güncel Tıbbi Araştırmaları Dergisi, c. 6, sy 1, Nisan 2026, ss. 13-18, doi:10.52818/cjmr.1870942.
Vancouver
1.Amine İrem Ağartıoğlu, Kadir Alper Küçüker, Ayşegül Aksu, Arif Atay, Bulent Turgut. Vertebral Hemangiomas Mimicking Metastases on Gallium-68 DOTATATE PET/CT: A Case of Gastric Neuroendocrine Tumor. GÜTAD. 01 Nisan 2026;6(1):13-8. doi:10.52818/cjmr.1870942