Araştırma Makalesi

Effect of complications on survival after lung cancer surgery

Cilt: 46 Sayı: 4 30 Aralık 2021
PDF İndir
EN TR

Effect of complications on survival after lung cancer surgery

Öz

Purpose: This study aims to investigate the effect of complications on survival after lung cancer surgery. Materials and Methods: This is a retrospective study of 802 patients who underwent surgical operations for lung cancer at two centers between January 2002 and December 2019. All patients were retrospectively evaluated according to age, gender, cancer stage, surgical technique, biochemical tests, pulmonary function tests, pulmonary risk index, length of the hospital stay, and the existing number of complications. Results: In total, 802 patients (%84 males, %16 females) with a mean age of 60 years (range 19-88 years) were included in the study. 5-year overall survival rate was 62.3%. 224 complications occurred in 180 patients (22.4%). The ten most common complications, respectively, were prolonged air leak (54), pneumonia (22), arrhythmia (19), respiratory failure (15), hemorrhage (17), atelectasis (10), pneumothorax-expansion defect (7), arrest (7) bronchopleural fistula (7), subileus-ileus (6). Cancer stage, the existing number of complications, advancing age, and tumor size are parameters that significantly affect survival. The occurs of one or more complications significantly adversely affects survival. Conclusion: Although the morbidity and mortality of lung cancer surgery have decreased in recent years, it is still high. Advanced stage lung cancer, advancing age, enlargement of tumor size and occurs of complications that negatively affect survival. Careful preoperative preparation may play a role in increasing long-term survival, as well as preventing complications, and decreasing early mortality.

Anahtar Kelimeler

Lung Cancer, Postoperative, Surgery, Complications

Kaynakça

  1. 1. Kozower BD. Complications of Thoracic Surgical Procedures. In: Locicero III J, Feins RH, Colson YL, Rocco G eds. General Thoracic Surgery. 8th ed. Philadelphia: Lippincott Williams and Wilkins; 2019:1211-35.
  2. 2. Allen MS, Darling GE, Pechet TT, Mitchell JD, Herndon JE, Landreneau RJ, et al. Morbidity and mortality of major pulmonary resections in patients with early-stage lung cancer: initial results of the randomized, prospective ACOSOG Z0030 trial. Ann Thorac Surg 2006;81(3):1013–19.
  3. 3. Salati M, Refai M, Pompili C, Xiume F, Sabbatini A, Brunelli A. Major morbidity after lung resection: a comparison between the European Society of Thoracic Surgeons Database system and the Thoracic Morbidity and Mortality system . J Thorac Dis. 2013;5(3):217-22.
  4. 4. Ernest G. Chan, Patrick G. Chan, Matthew J. Results of Surgical Treatment of Non-Small Cell Lung Cancer .In: Locicero III J, Feins RH, Colson YL, Rocco G, eds. General Thoracıc Surgery 8th ed. Philadelphia: Lippincott Williams and Wilkins; 2019:2572-73.
  5. 5. Rueth NM, Parsons HM, Haberman EB, Groth SS, Virnig BA, Tuttle TM, et al. Surgical treatment of lung cancer: predicting postoperative morbidity in the elderly population. J Thorac Cardiovasc Surg 2012;143(6):1314-23.
  6. 6. Karmakar MK, Ho AM. Postthoracotomy pain syndrome. Thorac Surg Clin 2004;14(3):345-52.
  7. 7. Yakşi E, Yakşi O. Current treatment options for post-thoracotomy pain syndrome: a review. Curr Thorac Surg 2017;2(3):103-10.
  8. 8. Thorpe A, Rodrigues J, Kavanagh J, Batchelor T, Lyen S. Postoperative complications of pulmonary resection. Clin Radiol. 2020;75(11):876.e1-876.e15.
  9. 9. Koehler RP, Kenan RJ. Management of postthoracotomy pain: acute and chronic. Thorac Surg Clin 2006;16:287-97.
  10. 10. Haithcock BE, Feins RH . Complications of Pulmonary Resection. In: Shields TW, Locicero III J, Reed CE, Feins RH, eds. General Thoracic Surgery. 7th ed. Philadelphia: Lippincott Williams and Wilkins; 2009:551-59.

Kaynak Göster

APA
Yakşi, O., Kılıçgün, A., Ersen, E., Sarbay, İ., Ünal, M., Turna, A., & Kaynak, K. (2021). Effect of complications on survival after lung cancer surgery. Cukurova Medical Journal, 46(4), 1588-1595. https://doi.org/10.17826/cumj.980951
AMA
1.Yakşi O, Kılıçgün A, Ersen E, vd. Effect of complications on survival after lung cancer surgery. Cukurova Med J. 2021;46(4):1588-1595. doi:10.17826/cumj.980951
Chicago
Yakşi, Osman, Ali Kılıçgün, Ezel Ersen, vd. 2021. “Effect of complications on survival after lung cancer surgery”. Cukurova Medical Journal 46 (4): 1588-95. https://doi.org/10.17826/cumj.980951.
EndNote
Yakşi O, Kılıçgün A, Ersen E, Sarbay İ, Ünal M, Turna A, Kaynak K (01 Aralık 2021) Effect of complications on survival after lung cancer surgery. Cukurova Medical Journal 46 4 1588–1595.
IEEE
[1]O. Yakşi vd., “Effect of complications on survival after lung cancer surgery”, Cukurova Med J, c. 46, sy 4, ss. 1588–1595, Ara. 2021, doi: 10.17826/cumj.980951.
ISNAD
Yakşi, Osman - Kılıçgün, Ali - Ersen, Ezel - Sarbay, İsmail - Ünal, Mehmet - Turna, Akif - Kaynak, Kamil. “Effect of complications on survival after lung cancer surgery”. Cukurova Medical Journal 46/4 (01 Aralık 2021): 1588-1595. https://doi.org/10.17826/cumj.980951.
JAMA
1.Yakşi O, Kılıçgün A, Ersen E, Sarbay İ, Ünal M, Turna A, Kaynak K. Effect of complications on survival after lung cancer surgery. Cukurova Med J. 2021;46:1588–1595.
MLA
Yakşi, Osman, vd. “Effect of complications on survival after lung cancer surgery”. Cukurova Medical Journal, c. 46, sy 4, Aralık 2021, ss. 1588-95, doi:10.17826/cumj.980951.
Vancouver
1.Osman Yakşi, Ali Kılıçgün, Ezel Ersen, İsmail Sarbay, Mehmet Ünal, Akif Turna, Kamil Kaynak. Effect of complications on survival after lung cancer surgery. Cukurova Med J. 01 Aralık 2021;46(4):1588-95. doi:10.17826/cumj.980951