Prematüre osteopenisi ile ABO kan grupları arasındaki ilişki

Yıl 2019, Cilt: 44 Sayı: Ek 1, 323 - 328, 29.12.2019

Ufuk Çakır Cüneyt Tayman Mehmet Büyüktiryaki

https://doi.org/10.17826/cumj.571122

Öz

Amaç: Çalışmamızda çok düşük doğum ağırlıklı (ÇDDA) prematürelerde kan grupları ile prematüre osteopenisi (PO) arasındaki ilişkiye bakılması amaçlanmıştır.  

Gereç ve Yöntem: Çalışmamız retrospektif hasta veri kayıtlarından 1 Ocak 2013 - 31 Aralık 2018 tarihleri arasında 3. düzey yenidoğan yoğun bakım ünitesinde yapıldı.  Çalışmaya gebelik haftası (GH) <32 hafta ve doğum ağırlığı (DA) <1500 g olan yenidoğanlar dahil edildi. Kan grupları O, A, B, AB olarak 4 ayrı gruba ayrıldı. Prematüre osteopenisi grubuna postanatal 1. ayda alkalen fosfataz düzeyleri > 700 IU / L olan bebekler dahil edildi.

Bulgular: Çalışmaya toplam 1567 ÇDDA prematüre bebek dahil edildi. Genel PO oranı %14,6 olarak bulundu. Prematüre osteopenisi oranları O kan grubunda %14,3, A kan grubunda %14,7, B kan grubunda %15,3 ve AB kan grubunda %13,2 olarak bulundu. Dört kan grubu PO açısından karşılaştırıldığında istatistiksel olarak anlamlı fark tespit edilmedi (p=0,612).

Sonuç: Çalışmamızda PO ile kan grubu arasındaki olası ilişkiye bakan ilk çalışma olup, PO için herhangi bir kan grubunun risk teşkil etmediği bulundu. 

Anahtar Kelimeler

Çok düşük doğum ağırlığı, ; osteopeni, prematüre, kan grubu

Destekleyen Kurum

Yazarlar finansal destek beyan etmemişlerdir

Relationship between osteopenia of prematurity and ABO blood groups

Öz

Purpose: The aim of this study was  to investigate the relationship between blood groups and osteopenia of prematurity (OOP) in very low birth weight (VLBW) infants. 

Materials and Methods: Our retrospective study was performed in the 3rd level neonatal intensive care unit between 1 January 2013 - 31 December 2018. Newborns with gestational age (GA) <32 weeks and birth weight (BW) <1500 g were included in the study. Infants were divided in to four groups according to blood groups (O, A, B, AB). Infants with alkaline phosphatase levels at postnatal first month > 700 IU / L were included in the OOP. 

Results: A total of 1567 preterm infants were included in the study. The overall OOP ratio was found to be 14.6%. The rates of OOP were 14.3% in the O blood group, 14.7% in the A blood group, 15.3% in the B blood group and 13.2% in the AB blood group. There was no statistically significant difference among four blood groups in terms of OOP (p=0.612).

Conclusion: Our study is the first study evaluated the possible relationship between OOP and blood group. We concluded that different type of blood groups were not related to the development of OOP.

Anahtar Kelimeler

Very low birth weight, ; osteopenia, premature, blood group

Kaynakça

• Referans1 Stalnaker KA, Poskey GA. Osteopenia of prematurity: does physical activity ımprove bone mineralization in preterm ınfants? Neonatal Netw. 2016;35:95-104.
• Referans2 Harrison CM, Gibson AT. Osteopenia in preterm infants. Arch Dis Child Fetal Neonatal Ed. 2013;98:F272-5.
• Referans3 Pieltain C, de Halleux V, Senterre T, Rigo J. Prematurity and bone health. World Rev Nutr Diet. 2013;106:181-8. Referans4 Choi JW, Pai SH. Associations between ABO blood groups and osteoporosis in postmenopausal women. Ann Clin Lab Sci. 2004;34:150-3.
• Referans5 Anstee DJ. The relationship between blood groups and disease. Blood. 2010;115:4635-43.
• Referans6 Liumbruno GM, Franchini M. Beyond immunohaematology: the role of the ABO blood group in human diseases. Blood Transfus. 2013;11:491-9.
• Referans7 Zhang H, Mooney CJ, Reilly MP. ABO blood groups and cardiovascular diseases. Int J Vasc Med. 2012;2012:641917.
• Referans8 Kaur M. Association between ABO blood group and osteoporosis among postmenopausal women of North India. Homo. 2014;65:516-21.
• Referans9 Lu BB, Li KH. Association between ABO blood groups and osteoporosis severity in Chinese adults aged 50 years and over. J Int Med Res. 2011;39:929-33.
• Referans10 Seyfizadeh N, Seyfizadeh N, Negahdar H, Hosseini SR, Nooreddini H, Parsian H. ABO blood group and prevalence of osteoporosis and osteopenia in the elderly population: an amirkola health and ageing project (AHAP)-based study. J Clin Densitom. 2018;21:200-204.
• Referans11 Hung YL, Chen PC, Jeng SF, Hsieh CJ, Peng SS, Yen RF, et al. Serial measurements of serum alkaline phosphatase for early prediction of osteopaenia in preterm infants. J Paediatr Child Health. 2011;47:134-9.
• Referans12 Agostoni C, Buonocore G, Carnielli VP, De Curtis M, Darmaun D, Decsi T, et al. Enteral nutrient supply for preterm infants: commentary from the European Society of Paediatric Gastroenterology, Hepatology and Nutrition Committee on Nutrition. J Pediatr Gastroenterol Nutr. 2010;50:85-91.
• Referans13 Faienza MF, D'Amato E, Natale MP, Grano M, Chiarito M, Brunetti G, et al. Metabolic Bone Disease of Prematurity: Diagnosis and Management. Front Pediatr. 2019;7:143.
• Referans14 King MJ. Blood group antigens on human erythrocytes – distribution, structure and possible functions. Biochim Biophys Acta. 1994;1197:15-44.
• Referans15 van der Voort DJ, Geusens PP, Dinant GJ. Risk factors for osteoporosis related to their outcome: fractures. Osteoporos Int. 2001;12:630-8.
• Referans16 Ewald DR, Sumner SC. Blood type biochemistry and human disease. Wiley Interdiscip Rev Syst Biol Med. 2016;8:517-35.