Purpose:To evaluate pregnancy outcomes in infertile women performed abdominal myomectomy at our clinic. Patients and Methods:This retrospective study included 76 infertile women underwent abdominal myomectomy. The cases were divided into two groups according to postoperative pregnancy (Group 1, n=22), and cases with no postoperative pregnancy (Group 2, n=54). Risk factors recorded were; age, parity, size of the fibroids, body mass index (BMI), tumor markers and serum blood values. Results:A total of 76 infertile women underwent abdominal myomectomy during the study period. Of all cases 22 (28.94 %) became pregnant. There was statically significant difference between the groups in terms of age, BMI, diameter of the fibroids (p5 cm the treatment modality should be abdominal myomectomy to increase the chance of postoperative pregnancy.
Marshall LM, Spiegelman D, Barbieri RL, Goldman MB, Manson JE, Colditz GA, Willett WC, Hunter DJ Variation in the incidence of uterine leiomyoma among premenopausal women by age and race Obstet Gynecol. 1997;90;967–73.
Pritts EA, Parker WH, Olive DL. Fibroids and infertility: an updated systematic review of the evidence. Fertil Steril. 2009;91:1215-23.
Hasan F, Arumugam K, Sivanesaratnam V. Uterine leiomyomata in pregnancy. Int J Gynecol. 1990;34:45–8.
Stovall DW, Parrish SB, Voorhis BJ, Hahn SJ, Sparks AE, Syrop CH. Uterine leiomyomas reduce the efficacy of assisted reproduction cycles: results of a matched follow-up study. Hum Reprod. 1998;13:192–
AD Geidam, ZM Lawan, C Chama, BG Bako. Indications and outcome of abdominal myomectomy in University of Maiduguri Teaching Hospital: Review of ten year. Niger Med J. 2011;52:193–7.
Poncelet C, Benifla JL, Batalian A, Darai E, Madelanat P. Myoma and infertility: analysis of the literature. Gynecol Obstet Fertil. 2002;29:450–1. http://www.wma.net/en/30publications/10policies/b3/1 7c.pdf
Bajekal N, Li TC. Fibroids, infertility and pregnancy wastage. Hum Reprod Update. 2000;6:614-20.
Gavai M, Berkes E, Lazar L, Fekete T, Takacs ZF, Urbancsek J, Papp Z. Factors affecting reproductive outcome following abdominal myomectomy. J Assist Reprod Genet. 2007;24:525-31.
Ezzati M, Norian JM, Segars JH. Management of uterine fibroids in the patient persuing assited reproductive technologies. Womens Health (Lond Engl) 2009;5:5413–21.
Yazışma Adresi / Address for Correspondence: Dr. Hasan Onur Topçu Zekai Tahir Burak Women Health Education and Research Hospital ANKARA E-mail: dronurtopcu@gmail.com. G eliş tarihi/Received on : 27.05.2014
Kabul tarihi/Accepted on: 20.06.2014
Abdominal myomektomi operasyonu geçiren infertil kadınlarda gebelik oranlarını etkileyen faktörler
Amaç:Kliniğimizde abdominal gebelik operasyonu geçiren infertil kadınlarda gebelik sonuçlarının irdelenmesidir Hastalar ve Yöntem:Bu retrospektif çalışma kliniğimizde abdominal myomektomi operasyonu geçiren 76 infertil kadın üzerinde yapılmıştır. Hastalar post-operatif gebelik oluşan (Grup 1;n:22) ve oluşmayan (Grup 2;n:54) olmak üzere iki gruba ayrılmıştır.Değerlendirilen klinik faktörler; yaş, parite,fibroid boyutu,vücut kitle indeksi,tümör markerları ve serum kan değerleridir. Bulgular:Çalışma süresince 76 infertil hasta abdominal myomektomi operasyonu geçirmiştir. Tüm hastaların 22 "si (% 28.94) gebe kalmıştır. Gruplar arasında yaş, VKİ ve fibroid boyutu açısından istatistiksel olarak anlamlı fark saptanmıştır (p
Marshall LM, Spiegelman D, Barbieri RL, Goldman MB, Manson JE, Colditz GA, Willett WC, Hunter DJ Variation in the incidence of uterine leiomyoma among premenopausal women by age and race Obstet Gynecol. 1997;90;967–73.
Pritts EA, Parker WH, Olive DL. Fibroids and infertility: an updated systematic review of the evidence. Fertil Steril. 2009;91:1215-23.
Hasan F, Arumugam K, Sivanesaratnam V. Uterine leiomyomata in pregnancy. Int J Gynecol. 1990;34:45–8.
Stovall DW, Parrish SB, Voorhis BJ, Hahn SJ, Sparks AE, Syrop CH. Uterine leiomyomas reduce the efficacy of assisted reproduction cycles: results of a matched follow-up study. Hum Reprod. 1998;13:192–
AD Geidam, ZM Lawan, C Chama, BG Bako. Indications and outcome of abdominal myomectomy in University of Maiduguri Teaching Hospital: Review of ten year. Niger Med J. 2011;52:193–7.
Poncelet C, Benifla JL, Batalian A, Darai E, Madelanat P. Myoma and infertility: analysis of the literature. Gynecol Obstet Fertil. 2002;29:450–1. http://www.wma.net/en/30publications/10policies/b3/1 7c.pdf
Bajekal N, Li TC. Fibroids, infertility and pregnancy wastage. Hum Reprod Update. 2000;6:614-20.
Gavai M, Berkes E, Lazar L, Fekete T, Takacs ZF, Urbancsek J, Papp Z. Factors affecting reproductive outcome following abdominal myomectomy. J Assist Reprod Genet. 2007;24:525-31.
Ezzati M, Norian JM, Segars JH. Management of uterine fibroids in the patient persuing assited reproductive technologies. Womens Health (Lond Engl) 2009;5:5413–21.
Yazışma Adresi / Address for Correspondence: Dr. Hasan Onur Topçu Zekai Tahir Burak Women Health Education and Research Hospital ANKARA E-mail: dronurtopcu@gmail.com. G eliş tarihi/Received on : 27.05.2014