Araştırma Makalesi

Prognostic Value of Lymph Node and Spleen Activity in [18F]FDG PET-CT in Lung Adenocarcinoma and Squamous Cell Carcinoma

Cilt: 46 Sayı: 1 3 Mart 2019
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Prognostic Value of Lymph Node and Spleen Activity in [18F]FDG PET-CT in Lung Adenocarcinoma and Squamous Cell Carcinoma

Öz

Objective: We aimed to investigate the prognostic value of primary mass, spleen and lymph node metabolic activity in [18F]FDG PET-CT as well as the prognostic value of neutrophil lymphocyte ratio (NLR) and platelet lymphocyte ratio (TLR) in patients with lung adenocarcinoma and squamous cell carcinoma.

Objective: We aimed to investigate the prognostic value of primary mass, spleen and lymph node metabolic activity in [18F]FDG PET-CT as well as the prognostic value of neutrophil lymphocyte ratio (NLR) and platelet lymphocyte ratio (TLR) in patients with lung adenocarcinoma and squamous cell carcinoma.

Results:  The  SUVmax  spleen/liver  and  SUVmax  lymph  node/liver  ratios  were  significantly  higher  in  the  exitus subgroup  of  squamous  cell  carcinoma  (p=0.025,  p=0.043;  respectively).  The  SUVmax  lymph  node/liver  ratio  was found to be a  predictor for  survival in squamous cell carcinoma (p=0.019, OR:1.282). The SUVmax spleen/liver and SUVmax lymph node/liver ratios were similar between subgroups of adenocancer. 
Conclusions:  The  SUV  ratios  of  the  spleen  were  not  a  predictor  for  survival  in  both  groups.  The  SUVmax  lymph node/liver ratio was found to be a predictor for survival in squamous cell carcinoma. However, NLR and PLR were not found to be prognostic factors. 

Anahtar Kelimeler

Kaynakça

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  7. 7. Prévost S, Boucher L, Larivée P, et all. Bone marrow hypermetabolism on 18F-FDG PET as a survival prognostic factor in non small cell lung cancer. 2006; 4:559-65.
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Ayrıntılar

Birincil Dil

İngilizce

Konular

Sağlık Kurumları Yönetimi

Bölüm

Araştırma Makalesi

Yazarlar

Halil Komek Bu kişi benim
Türkiye

Zuhat Urakci Bu kişi benim

Serdar Altindag Bu kişi benim

Yayımlanma Tarihi

3 Mart 2019

Gönderilme Tarihi

2 Temmuz 2018

Kabul Tarihi

-

Yayımlandığı Sayı

Yıl 2019 Cilt: 46 Sayı: 1

Kaynak Göster

APA
Komek, H., Akdeniz, N., Urakci, Z., Can, C., & Altindag, S. (2019). Prognostic Value of Lymph Node and Spleen Activity in [18F]FDG PET-CT in Lung Adenocarcinoma and Squamous Cell Carcinoma. Dicle Medical Journal, 46(1), 1-10. https://doi.org/10.5798/dicletip.534806
AMA
1.Komek H, Akdeniz N, Urakci Z, Can C, Altindag S. Prognostic Value of Lymph Node and Spleen Activity in [18F]FDG PET-CT in Lung Adenocarcinoma and Squamous Cell Carcinoma. diclemedj. 2019;46(1):1-10. doi:10.5798/dicletip.534806
Chicago
Komek, Halil, Nadiye Akdeniz, Zuhat Urakci, Canan Can, ve Serdar Altindag. 2019. “Prognostic Value of Lymph Node and Spleen Activity in [18F]FDG PET-CT in Lung Adenocarcinoma and Squamous Cell Carcinoma”. Dicle Medical Journal 46 (1): 1-10. https://doi.org/10.5798/dicletip.534806.
EndNote
Komek H, Akdeniz N, Urakci Z, Can C, Altindag S (01 Mart 2019) Prognostic Value of Lymph Node and Spleen Activity in [18F]FDG PET-CT in Lung Adenocarcinoma and Squamous Cell Carcinoma. Dicle Medical Journal 46 1 1–10.
IEEE
[1]H. Komek, N. Akdeniz, Z. Urakci, C. Can, ve S. Altindag, “Prognostic Value of Lymph Node and Spleen Activity in [18F]FDG PET-CT in Lung Adenocarcinoma and Squamous Cell Carcinoma”, diclemedj, c. 46, sy 1, ss. 1–10, Mar. 2019, doi: 10.5798/dicletip.534806.
ISNAD
Komek, Halil - Akdeniz, Nadiye - Urakci, Zuhat - Can, Canan - Altindag, Serdar. “Prognostic Value of Lymph Node and Spleen Activity in [18F]FDG PET-CT in Lung Adenocarcinoma and Squamous Cell Carcinoma”. Dicle Medical Journal 46/1 (01 Mart 2019): 1-10. https://doi.org/10.5798/dicletip.534806.
JAMA
1.Komek H, Akdeniz N, Urakci Z, Can C, Altindag S. Prognostic Value of Lymph Node and Spleen Activity in [18F]FDG PET-CT in Lung Adenocarcinoma and Squamous Cell Carcinoma. diclemedj. 2019;46:1–10.
MLA
Komek, Halil, vd. “Prognostic Value of Lymph Node and Spleen Activity in [18F]FDG PET-CT in Lung Adenocarcinoma and Squamous Cell Carcinoma”. Dicle Medical Journal, c. 46, sy 1, Mart 2019, ss. 1-10, doi:10.5798/dicletip.534806.
Vancouver
1.Halil Komek, Nadiye Akdeniz, Zuhat Urakci, Canan Can, Serdar Altindag. Prognostic Value of Lymph Node and Spleen Activity in [18F]FDG PET-CT in Lung Adenocarcinoma and Squamous Cell Carcinoma. diclemedj. 01 Mart 2019;46(1):1-10. doi:10.5798/dicletip.534806