The use of empirical antibiotics in intensive care unit and relationship between nutrition and the incidence of infection

Salih Yıldırım; Yavuz Orak; Rukiye Menemencioğlu; Ahmet Altun; Filiz Orak; Cevdet Düger; Esra Özpay; Fatih Mehmet Yazar

doi:10.5798/dicletip.620514

The use of empirical antibiotics in intensive care unit and relationship between nutrition and the incidence of infection

Öz

Objective: Aim of study is to determine which antibiotic is started empirically in the ICU and to investigate whether the antibiotic started according to culture result was changed or not and the effect of this change on mortality, and to investigate the relationship between mortality and infection by determining whether enteral and parenterally fed patients have attained sufficient calorie level.

Method: After the approval of the local ethics committee, the files of 476 patients hospitalized in our hospital were retrospectively reviewed. A total of 159 patients over 18 years of age who received mechanical ventilation therapy for at least 3 days were included in the study. Blood, urine and tracheal aspirate culture were determined. It was recorded whether antibiotics had changed according to the culture result. Nutritional patterns, number of feeding days and basal caloric need were determined. It was investigated whether basal calorie need was met on 1, 3 and 5 days. Factors affecting mortality were investigated.

Results: Antibiotic exchange was significantly higher in the patients who died (P = 0.002). Mortality was higher in patients who were unable to reach the target calorie (P = 0.01). Empirical changes in antibiotics (r: 0.174, P = 0.028), and culture positivity (r: 0.177, P = 0.026) were associated with mortality (r: 0.195, P = 0.014). In the subgroup analysis, reproduction in tracheal aspirate culture was an important factor affecting mortality (r: 0.211 P: 0.008).

Conclusions: The number of days of hospitalization, antibiotic change, culture positivity and inability to reach the target calories in nutrition are associated with mortality in the intensive care unit.

Anahtar Kelimeler

empirical antibiotic therapy,mortality,intensive care unit

Kaynakça

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Ayrıntılar

Birincil Dil

İngilizce

Konular

Sağlık Kurumları Yönetimi

Bölüm

Araştırma Makalesi

Yazarlar

Salih Yıldırım Bu kişi benim
0000-0002-4986-6812

Yavuz Orak ^* Bu kişi benim
0000-0002-8356-6223

Rukiye Menemencioğlu Bu kişi benim
0000-0002-7053-8143

Ahmet Altun Bu kişi benim
0000-0003-2056-8683

Filiz Orak Bu kişi benim
0000-0001-5153-7391

Cevdet Düger Bu kişi benim
0000-0002-3845-8733

Esra Özpay Bu kişi benim
0000-0003-0187-9910

Fatih Mehmet Yazar Bu kişi benim
0000-0002-1780-6962

Yayımlanma Tarihi

16 Eylül 2019

Gönderilme Tarihi

11 Nisan 2019

Kabul Tarihi

11 Temmuz 2019

Yayımlandığı Sayı

Yıl 2019 Cilt: 46 Sayı: 3

DOI

https://doi.org/10.5798/dicletip.620514

IZ

https://izlik.org/JA27FX48HJ

Kaynak Göster

RIS / Bibtex

APA

Yıldırım, S., Orak, Y., Menemencioğlu, R., Altun, A., Orak, F., Düger, C., Özpay, E., & Yazar, F. M. (2019). The use of empirical antibiotics in intensive care unit and relationship between nutrition and the incidence of infection. Dicle Medical Journal, 46(3), 489-498. https://doi.org/10.5798/dicletip.620514

AMA

1.Yıldırım S, Orak Y, Menemencioğlu R, vd. The use of empirical antibiotics in intensive care unit and relationship between nutrition and the incidence of infection. diclemedj. 2019;46(3):489-498. doi:10.5798/dicletip.620514

Chicago

Yıldırım, Salih, Yavuz Orak, Rukiye Menemencioğlu, vd. 2019. “The use of empirical antibiotics in intensive care unit and relationship between nutrition and the incidence of infection”. Dicle Medical Journal 46 (3): 489-98. https://doi.org/10.5798/dicletip.620514.

EndNote

Yıldırım S, Orak Y, Menemencioğlu R, Altun A, Orak F, Düger C, Özpay E, Yazar FM (01 Eylül 2019) The use of empirical antibiotics in intensive care unit and relationship between nutrition and the incidence of infection. Dicle Medical Journal 46 3 489–498.

IEEE

[1]S. Yıldırım vd., “The use of empirical antibiotics in intensive care unit and relationship between nutrition and the incidence of infection”, diclemedj, c. 46, sy 3, ss. 489–498, Eyl. 2019, doi: 10.5798/dicletip.620514.

ISNAD

Yıldırım, Salih - Orak, Yavuz - Menemencioğlu, Rukiye - Altun, Ahmet - Orak, Filiz - Düger, Cevdet - Özpay, Esra - Yazar, Fatih Mehmet. “The use of empirical antibiotics in intensive care unit and relationship between nutrition and the incidence of infection”. Dicle Medical Journal 46/3 (01 Eylül 2019): 489-498. https://doi.org/10.5798/dicletip.620514.

JAMA

1.Yıldırım S, Orak Y, Menemencioğlu R, Altun A, Orak F, Düger C, Özpay E, Yazar FM. The use of empirical antibiotics in intensive care unit and relationship between nutrition and the incidence of infection. diclemedj. 2019;46:489–498.

MLA

Yıldırım, Salih, vd. “The use of empirical antibiotics in intensive care unit and relationship between nutrition and the incidence of infection”. Dicle Medical Journal, c. 46, sy 3, Eylül 2019, ss. 489-98, doi:10.5798/dicletip.620514.

Vancouver

1.Salih Yıldırım, Yavuz Orak, Rukiye Menemencioğlu, Ahmet Altun, Filiz Orak, Cevdet Düger, Esra Özpay, Fatih Mehmet Yazar. The use of empirical antibiotics in intensive care unit and relationship between nutrition and the incidence of infection. diclemedj. 01 Eylül 2019;46(3):489-98. doi:10.5798/dicletip.620514