Skin prick test results of atopic asthmatic subjects in a chest disease clinic in Sanliurfa

Öz

Objective: Skin prick test (SPT) is used widely to determine the allergens in atopic patients. In this study, we aimed to determine the spectrum of aeroallergen sensitivity of atopic asthmatic subjects in Şanlıurfa district.

Methods: We evaluated clinical, demographic findings and SPT results of 95 male and 162 female in a total 257 patients who had asthma and allergic symptoms.

Results: Most common allergens causing a sensitivity reaction detected in our clinic were as follows; cockroach (56.8%), wheat pollen (53.3%), corn pollen (47.4%), grass pollen (36.5%), poplar tree pollen (26%), house dust mite (19.4%), pepper (16.7%) and cat dander (15.1%).

Conclusion: High levels of sensitivity to wheat and corn pollens and relatively low sensitivity levels of cat dander results meet our expectations in the area of agricultural land and where pet ownership is not common.

Key words: Atopy, aeroallergens, skin prick test

Anahtar Kelimeler

• Atopy, aeroallergens, skin prick test

Skin prick test results of atopic asthmatic subjects in a chest disease clinic in Sanliurfa Şanlıurfa’da bir göğüs hastalıkları kliniğinde atopik astımlı hastaların allerji deri testi sonuçları

Öz

Amaç: Allerji deri testi atopik hastaların değerlendirilmesinde sık kullanılmakta ve hızlı sonuç alınabilmektedir. Bu çalışmada amacımız Şanlıurfa’da atopik astımlı hastaların aeroallerjen duyarlılığını değerlendirmektir.Yöntemler: Çalışmada 95 erkek, 162 kadın toplamda 257 atopik astımlı hastanın klinik, demografik verileri ile deri prick testi sonuçları geriye dönük olarak değerlendirildi.Bulgular: Yapılan deri prick testinde en sık allerjiye yol açan allerjenler sırasıyla; hamam böceği (%56,8), buğday poleni (%53,3), mısır poleni (%47,4), çimen poleni(%36,5), kavak ağacı poleni (%26), ev tozu akarı (%19,4), biber tozu (%16,7) ve kedi tüyü (%15,1) olarak saptandı.Sonuç: Buğday ve mısır polenine yüksek oranda duyarlılık, kedi tüyüne ise daha az oranda duyarlılık saptanması tarımla uğraşan ve kedi besleme alışkanlıkları sık olmayan bölgede beklentilerimizi karşılamaktadır

Anahtar Kelimeler

• Atopi, aeroallerjenler, deri allerji testi

Kaynakça

1. Boulet LP, FitzGerald JM, Reddel HK. The revised 2014
2. GINA strategy report: opportunities for change. Curr Opin
3. Pulm Med 2014;21:1-7.
4. Arruda LK, Barbosa MC, Santos AB, et al. Recombinant
5. allergens for diagnosis of cockroach allergy. Curr Allergy
6. Asthma Rep 2014;14:1-11
7. Gandhi VD, Vliagoftis H. Airway epithelium interactions
8. with aeroallergens: role of secreted cytokines and chemokines in innate immunity. Front Immunol 2015;6:147.

9. Craig TJ., Aeroallergen sensitization in asthma: prevalence and correlation with severity. Allergy Asthma Proc
10. ;31:96-102.
11. Heinzerling L, Mari A, Bergmann KC. et al. The skin prick
12. test - European standards. Clin Transl Allergy 2013;3:3.
13. Aas K, Belin L. Standardization of diagnostic work in allergy. Int Arch Allergy Appl Immunol1973;45:57-60.
14. Jeong KY, Son M, Lee JH, et al. Allergenic characterization
15. of a novel allergen, homologous to chymotrypsin, from german cockroach. Allergy Asthma Immunol Res 2015;7:283-289.
16. Mungan D, Celik G, Sin B. et al. Characteristic features of
17. cockroach hypersensitivity in Turkish asthmatic patients. Allergy 1998; 53: 870-3.
18. Pefura-Yone EW, Kengne AP, Afane-Ze E, Kuaban C. Sensitisation to Blattella germanica among adults with asthma in
19. Yaounde, Cameroon: a cross-sectional study. World Allergy
20. Organ J 2014:7:22.
21. Uzel A, Çapan N, Canbakan S, et al. Evaluation of the relationship between cockroach sensitivity and house-dust-
22. mite sensitivity in Turkish asthmatic patients. Respiratory
23. Medicine 2005;99:1032-1037.
24. Çölgeçen E, Özyurt K, İntepe YS. et al. Skin prick test results in patients with atopic symptoms in Yozgat district. JCEI 2014;5: 64-68.
25. Bayram N, Uyar M, Elbek O, et al. Allergy skin test results
26. of an outpatient pulmonary clinic in Gaziantep. Gaziantep Med J 2013;19:152-154
27. Farrokhi S, Gheybi MK, Movahed A. et al. Common aeroallergens in patients with asthma and allergic rhinitis living
28. in southwestern part of iran: based on skin prick test reactivity. Iran J Allergy Asthma Immunol 2014;14:133-138.
29. Erkan C. Asthma exacerbation related with inhalation of hot
30. peppers extract (capsaicin). JCEI 2013;4:331-334.
31. Custovic, Custovic A, Taggart SC, Woodcock A. House
32. dust mite and cat allergen in different indoor environments.
33. Clin Exp Allergy 1994;24:1164-1168.