The “Eye of the tiger sign” in Progressive Supranuclear Palsy: Is it a coincidence or not?

Yıl 2023, , 595 - 600, 12.02.2024

Hamit Genç , Nevra Öksüz , Okan Doğu

https://doi.org/10.46871/eams.1322881

Öz

Progressive supranuclear palsy (PSP); is a neurodegenerative disorder involved in atypical parkinsonism syndromes. The classical clinical presentation is postural instability, falls, downward paralysis, frontal dementia, and symmetric akinetic-rigid parkinsonism. The atrophy of the mesencephalon in magnetic resonance imaging (MRI) is an important marker in diagnosing the disease. Recently, a few PSP cases reported the “eye of the tiger” sign on MRI. The “eye of the tiger” sign, in globus pallidus, is a sign that bilaterally symmetrically located low signal intensity and central longitudinal hyperintensity are observed. While previously a specific finding for the pantothenate kinase-associated neurodegeneration (PKAN), it is no longer considered specific because of the reported cases of non-PKAN with the “eye of the tiger” sign such as neuropherritinopathy, multi-system atrophy, corticobasal degeneration. In this report, we aimed to contribute to the literature by presenting two PSP cases in which the “eye of the tiger” sign was observed.

Anahtar Kelimeler

Progressive supranuclear palsy, the “eye of the tiger” sign, iron accumulation

Proje Numarası

Yok

Kaynakça

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