İnfertilite tedavisinde semendeki yuvarlak hücre yoğunluğu gebeliği etkileyen bir faktör müdür?

Öz

Amaç: Spermiyogram değerlendirmesi sırasında görülen yuvarlak hücreler, gebelik sonuçlarını etkileme potansiyeline sahip hücrelerdir. Bu çalışmada, erkek kaynaklı infertilite ve açıklanamayan infertilite nedeniyle üremeye yardımcı tedavi merkezimize başvuran hastaların semen örneklerinde yuvarlak hücre yoğunluğunun gebelik sonuçları üzerindeki etkisi değerlendirildi. Yöntem: Gaziantep Cengiz Gökçek Kadın Doğum ve Çocuk Hastalıkları Hastanesi Üremeye Yardımcı Tedavi Merkezine 02/01/2022 ile 01/01/2023 tarihleri arasında in vitro fertilizasyon ve intrauterin inseminasyon için başvuran erkeklerde yuvarlak hücre açısından retrospektif bir çalışma yapıldı. Erkek kaynaklı infertilite tanısı alan 75 vaka ve açıklanamayan infertilite tanısı alan 23 vaka olmak üzere toplam 98 vaka analiz edilmiştir. İstatistiksel analiz IBM SPSS Statistics 25.0 programı yardımıyla yapıldı ve p<0.05 değerleri anlamlı olarak kabul edildi. Bulgular: Açıklanamayan infertilite ve erkeğe bağlı infertilite hastalarında, gebelik sonucuna göre yuvarlak hücre yoğunluğu açısından istatistiksel olarak anlamlı bir fark gözlenmedi (p=0.140, p=0.919). Sonuç: Çalışmamızın sonucunda açıklanamayan infertilite ve erkek ilişkili infertilite olgularında yuvarlak hücre yoğunluğunun gebelik sonuçlarını etkilemediği görüldü.

Anahtar Kelimeler

• yuvarlak hücre
• açıklanamayan infertilite
• erkek kaynaklı infertilite
• gebelik oranı
• semen

Is round cell density in semen a factor affecting pregnancy in infertility treatment?

Öz

Purpose: Round cells seen during spermiogram evaluation are cells that have the potential to affect pregnancy outcomes. In this study, we evaluated the effect of round cell density on pregnancy outcome in semen samples of patients admitted to our assisted reproductive treatment center for male-induced infertility and unexplained infertility. Methods: A retrospective study was conducted in terms of round cell in men who applied to Gaziantep Cengiz Gökçek Gynecology and Obstetrics and Pediatrics Hospital, Assisted Reproductive Treatment Center for in vitro fertilization and intrauterine insemination between 02/01/2022 and 01/01/2023. A total of 98 cases were analyzed: 75 cases with a diagnosis of male-induced infertility and 23 cases with a diagnosis of unexplained infertility. Statistical analysis was performed with the help of IBM SPSS Statistics 25.0 program and p<0.05 values were accepted as significant. Results: In unexplained infertility and male-related infertility patients, no statistically significant difference was observed in terms of round cell cell density according to pregnancy outcome (p=0.140, p=0.919). Conclusion: As a result of our study, it was observed that round cell cell density did not affect pregnancy outcomes in unexplained infertility and male-related infertility cases.

Anahtar Kelimeler

• semen
• round cell
• unexplained infertility
• male infertility
• pregnancy rate

Kaynakça

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