The Prognostic Value of Inflammatory Indices and the HALP Score in Aortic Dissection

Öz

Introduction: Aortic dissection is critical, and recent studies increasingly highlight the prognostic value of laboratory parameters alongside diagnostic CT angiography. Materials and Methods: This study included 23 adult patients diagnosed with aortic dissection between January 2023 and January 2025, analyzing the association between admission lab data, derived scores, and outcomes like mortality and ICU stay. Results: Neutrophil count was found to be significantly higher in patients who died (p = 0.03), with 57.1% sensitivity and 68.8% specificity in predicting mortality. A significant negative correlation was found between HALP score and ICU length of stay (r = –0.471, p = 0.023), whereas CRP levels were positively correlated with ICU stay duration (r = 0.504, p = 0.014). Conclusion: Neutrophil count, HALP score, and CRP levels may serve as useful biomarkers for predicting the prognosis of aortic dissection and aiding early risk stratification

Anahtar Kelimeler

• HALP score
• Aortic dissection
• prognosis

Akut Aort Diseksiyonunda İnflamatuvar İndeksler ve HALP Skorunun Prognostik Değeri

Öz

Giriş: Aort diseksiyonu kritik bir klinik tablodur ve son yıllarda yapılan çalışmalar, tanısal BT anjiyografinin yanında laboratuvar parametrelerinin prognostik değerini giderek daha fazla vurgulamaktadır. Gereç ve Yöntem: Bu çalışmaya Ocak 2023 – Ocak 2025 tarihleri arasında aort diseksiyonu tanısı alan 23 erişkin hasta dâhil edilmiştir. Hastaların başvuru anındaki laboratuvar verileri ve bu verilerden türetilen skorlar ile mortalite ve yoğun bakım yatış süresi gibi klinik sonuçlar arasındaki ilişki değerlendirilmiştir. Bulgular: Mortalite gelişen hastalarda nötrofil sayısı anlamlı olarak daha yüksek bulunmuştur (p = 0.03) ve mortaliteyi öngörmede %57.1 duyarlılık ve %68.8 özgüllük göstermiştir. HALP skoru ile yoğun bakım yatış süresi arasında anlamlı negatif korelasyon saptanmıştır (r = –0.471, p = 0.023). Buna karşılık, CRP düzeyleri ile yoğun bakımda kalış süresi arasında anlamlı pozitif korelasyon mevcuttur (r = 0.504, p = 0.014). Sonuç: Nötrofil sayısı, HALP skoru ve CRP düzeyleri, aort diseksiyonunun prognozunun öngörülmesinde ve erken risk sınıflandırmasında yararlı biyobelirteçler olarak kullanılabilir.

Anahtar Kelimeler

• HALP skoru
• aort diseksiyonu
• prognoz

Kaynakça

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