Ankaferd blood stopper: Gastrointestinal kanamalarda yeni bir topikal hemostatik ajan

Öz

Gastrointestinal sistem kanaması ağızdan anal kanala kadar olan gastrointestinal alanın çeşitli patolojilerine bağlı olarak oluşur. Endoskopik, hemostatik ve farmakolojik tekniklere rağmen peptik ülsere bağlı mortalite halen %5-%10 civarındadır. Ankaferd blood stopper yeni ve başarılı bir topikal hemostatik ajandır. Ankaferd blood stopper ülkemizde yetişen Thymus vulgaris, Glycyrrhiza glabra, Vitis vinifera, Alpinia officinarum, and Urtica dioica bitkilerinin karışımından oluşmaktadır. Özellikle yönetimi zor olan gastrointestinal kanamalarda başarısı çeşitli çalışmalarla kanıtlanmıştır.

Anahtar Kelimeler

• Ankaferd blood stopper,gastrointestinal kanama,hemostaz

The Ankaferd blood stopper: A novel topical hemostatic agent in gastrointestinal bleeding

Öz

Gastrointestinal bleeding refers to any hemorrhage ascribed to the pathologies of the gastrointestinal tract, extending from the mouth to the anal canal. Despite the recent improvements in the endoscopic, hemostatic, and adjuvant pharmacologic techniques, the reported mortality for peptic ulcer bleeding is still around 5%-10%. The Ankaferd blood stopper, a novel topical hemostatic agent, is a standardized mixture of the plants Thymus vulgaris, Glycyrrhiza glabra, Vitis vinifera, Alpinia officinarum, and Urtica dioica found in Anatolia, Turkey. Ankaferd blood stopper offers a successful option, specifically for “difficult-to-manage” situations, as evidenced by the data presented in several studies.

Anahtar Kelimeler

• Ankaferd blood stopper,gastrointestinal bleeding,hemostasis

Kaynakça

1. 1. Beyazit Y, Kekilli M, Haznedaroglu IC, et al. Ankaferd hemostat in the management of gastrointestinal hemorrhages. World J Gastroenterol 2011;17:3962-70.
2. 2. Raphaeli T, Menon R. Current treatment of lower gastrointestinal hemorrhage. Clin Colon Rectal Surg 2012;25:219-27.
3. 3. Gungor G1, Goktepe MH, Biyik M, et al. Efficacy of Ankaferd blood stopper application on non-variceal upper gastrointestinal bleeding. World J Gastrointest Endosc 2012;4:556-60.
4. 4. Goker H, Haznedaroglu IC, Ercetin S, et al. Haemostatic actions of the folkloric medicinal plant extract, Ankaferd Blood Stopper. J Int Med Res 2008;36:163-70.
5. 5. Kurt M, Akdogan M, Ibis M, Haznedaroglu IC. Ankaferd blood stopper for gastrointestinal bleeding. J Invest Surg 2010;23:239.