Sepsis Patogenezi, Tanı ve Tedavisi Sepsiste Oksidatif Stres ve Sepsis İnflamasyon İlişkisi, Sepsiste Deneysel Modeller

Öz

Sepsis hem beşerî hekimlik hem de veteriner hekimlikte yüksek ölüm oranları ile seyreden önemli bir sistemik ce-vaptır. Bu derleme makalede; sepsisin patogenezi, etiyolojisi, epidemiyolojisi, teşhis ve tedavi yöntemlerinden bahsedil-mektedir. Bunun yanında, sistemik inflamatuvar cevap ile sepsis ilişkisi, oksidatif stresin sebepleri, oluşumu ve sepsisle olan bağlantısı ve farmakolojide deneysel olarak uygulanan sepsis modelleri hakkında bilgi verilmesi amaçlanmıştır.

Anahtar Kelimeler

• İnflamasyon
• oksidatif stres
• sepsis

Sepsis Pathogenesis, Diagnosis and Treatment. Oxidative Stress in Sepsis and Sepsis Inflammation Relation. Experimental Models in Sepsis

Öz

Sepsis is an important systemic response with high mortality rates in both human medicine and veterinary medicine. In this seminar, Pathogenesis, etiology, epidemiology, diagnosis, and treatment of sepsis are mentioned. In addition, it was aimed to give information about the relationship between systemic inflammatory response and sepsis, the causes of oxidative stress, its formation and connection with sepsis, and experimental sepsis models in pharmacology.

Anahtar Kelimeler

• Inflammation
• oxidative stress
• sepsis

Kaynakça

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