COVID-19, VARYANTLAR VE GÜNCELLENEN AŞILAR

Öz

SARS-CoV-2, hastaneye yatış ve mortalite de dahil olmak üzere ciddi sonuçları olabilen bir virüstür. Özellikle yaşlılar ve altta yatan tıbbi rahatsızlıkları olan kişilerin ciddi sonuçlarla karşılaşma riski yüksektir. SARS-CoV-2’nin, yıl boyunca öngörülemeyen zamanlarda dolaşımının devam etmesini kolaylaştıran mutasyonlar edinme yeteneğine sahip olmaya devam ettiği görülmektedir. Varyantların ortaya çıkışı, COVID-19 bulaşı ve hastalık şiddetini tespit etmek için birinci ve ikinci basamak sağlık hizmetlerinde sürveyans sistemlerini güçlendirerek SARS-CoV-2'ye karşı sürekli tetikte olmanın önemini göstermektedir. Mümkünse alınan tüm SARS-CoV-2 pozitif örnekler, dolaşımdaki varyantların düzenli olarak izlenmesini kolaylaştırmak için sıralanmalı ve rapor edilmelidir. Dünya Sağlık Örgütü şu anda, ilgi çeken üç varyant ve izlenmekte olan yedi varyant dahil olmak üzere çeşitli SARS- CoV-2 varyantlarını izlemektedir. COVID-19’un ciddi sonuçlarına karşı daha iyi koruma sağlayabilmek için COVID-19 aşı içeriğinin güncellenmesi gerekliliği ortaya çıkmış ve aşıların uygulanması için yeni rehberler geliştirilmiştir. Derlemenin amacı, COVID-19 için dolaşımdaki varyantları, bu varyantlar değerlendirilerek hazırlanan güncellenen aşı içeriğini ve aşılamadaki hedef grupları özetleyebilmektedir. Dünya Sağlık Örgütü hastalığın izlenmesinin devam edilmesinin önemini vurgulamaktadır.

Anahtar Kelimeler

• COVID-19
• aşılanma
• varyantlar
• Dünya Sağlık Örgütü

COVID-19, VARIANTS AND UPDATED VACCINES

Öz

SARS-CoV-2 is a virus that can have serious consequences, including hospitalization and mortality. The elderly and people with underlying medical conditions are at particularly high risk of serious consequences. SARS-CoV-2 appears to continue to have the ability to acquire mutations that facilitate its continued circulation at unpredictable times throughout the year. The emergence of variants demonstrates the importance of constant vigilance against SARS-CoV-2 by strengthening primary and secondary healthcare surveillance systems to detect COVID-19 transmission and disease severity. If possible, all SARS-CoV-2 positive samples received should be sequenced and reported to facilitate regular monitoring of circulating variants. The World Health Organization is currently monitoring several SARS-CoV-2 variants, including three variants of interest and seven variants under monitoring. For better protection against the serious consequences of COVID-19, the COVID-19 vaccine content needs to be updated and new guidelines for the administration of vaccines have been developed. This review aims to summarize the variants in circulation for COVID-19, the updated vaccine content based on these variants, and the target groups for vaccination. The World Health Organization emphasizes the importance of continued monitoring of the disease.

Anahtar Kelimeler

• COVID-19
• vaccination
• variants
• World Health Organization

Kaynakça

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