3-YEAR FOLLOW-UP OF REGENERATIVE ENDODONTIC TREATMENTS WITH THE APPLICATION OF CONCENTRATED GROWTH FACTOR AS SCAFFOLD: NINE CASES

Öz

The aim of this case series is to present 3-year clinical and radiographic follow-ups of nine regenerative endodontic treatment cases using concentrated growth factor in necrotic immature permanent teeth. Nine patients aged 8-21 years were referred to our clinic. According to clinical and radiographic examinations, it was decided to perform RET. After the working length determination, teeth were irrigated with 2.5% NaOCl and activated with EndoActivator. Root canals were instrumented with XP-endo Finisher-R file. 20 mL of 17% EDTA was used as final irrigation, and calcium hydroxide and temporary fillings were placed. Two weeks later, roots were irrigated with 17% EDTA and 5 mL distilled water and dried with paper points. Bleeding was induced into the coronal part of the root canal. Concentrated growth factor (obtained from the patient’s blood) was placed into the root canals. Biodentine was placed on the blood clot and permanent restorations were made with resin composite. At 3-year follow-up, clinical and radiographic healing was observed in 5 patients. In the other 4 patients, persistent infection and sinus-tract formation were detected at different time periods. Although RET is a promising treatment that aims to preserve teeth vitally, more randomized clinical research is needed due to its unpredictable results.

Anahtar Kelimeler

• concentrated growth factor
• immature necrotic permanent tooth
• regenerative endodontic treatment

KONSANTRE BÜYÜME FAKTÖRÜ KULLANILARAK YAPILAN REJENERATİF ENDODONTİK TEDAVİLERİN ÜÇ YILLIK TAKİBİ: DOKUZ ADET OLGU

Öz

Bu olgu serisinin amacı, apeksi açık nekrotik daimi dişlerde konsantre büyüme faktörü kullanılarak gerçekleştirilen dokuz adet rejeneratif endodontik tedavi olgusunun 3 yıllık klinik ve radyografik takiplerini sunmaktır. Yaşları 8-21 arasında değişen 9 hasta kliniğimize başvurdu. Yapılan klinik ve radyografik muayeneler sonucunda rejeneratif endodontik tedavi yapılmasına karar verildi. Çalışma boyu tespitinden sonra dişler 20 mL %2.5 NaOCl ile irige edildi ve EndoActivator ile aktive edildi. Kök kanalları XP-endo Finisher-R eğesi ile enstrümante edildi. Final irrigasyonu olarak 20 mL %17 EDTA kullanıldı, ardından kalsiyum hidroksit ve geçici dolguları yerleştirildi. İki hafta sonra kökler 20 mL %17 EDTA ve 5 mL distile su ile irige edildi ve kağıt konlar ile kurutuldu. Kök kanallarının koronal kısmına kadar kanama gerçekleştirildi. Hastadan kan alınarak elde edilen konsantre büyüme faktörü kök kanallarına yerleştirildi. Oluşan kan pıhtısının üzerine Biodentine yerleştirildi ve rezin kompozit ile daimi restorasyonları yapıldı. 3 yıllık takipte 5 hastada klinik ve radyografik iyileşme gözlendi. Diğer 4 hastada farklı zaman dilimlerinde persiste enfeksiyon ve sinüs yolu oluşumu saptandı. Rejeneratif endodontik tedaviler dişleri canlı olarak korumayı amaçlayan ve gelecek vadeden tedaviler olsa da öngörülemeyen sonuçları nedeni ile daha fazla randomize klinik araştırmaya ihtiyaç vardır.

Anahtar Kelimeler

• apeksi açık daimi nekrotik diş
• konsantre büyüme faktörü
• rejeneratif endodontik tedavi

Kaynakça

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