IS THERE A RELATION BETWEEN ZINC LEVELS, AND RECURRENT RESPIRATORY SYSTEM I NFECTIONS IN CHILDREN?

Öz

Amaç: Eser elementlerin ve D vitaminin eksik alımı ve allerji çocuk solunum sistemi sağlığı üzerine etkileri bulunmaktadır. Kesitsel çalışmamızda tekrar eden solunum yolun yolu enfeksiyonu ile çinko düzeyleri ve neden olabilecek diğer faktörlerin ilişkisini araştırmak amaçlanmaktadır. Metod: 2015-2017 tekrar eden akut otitis media, farenjit, rinit gibi üst solunum yolu enfeksiyonu ve alt solunum yolu enfeksiyonu olan, Türkiye’de yaşayan 249 olgu ve 122 sağlıklı kontrol çalışmaya dahil edilmiştir. Çinko düzeyleri, adenoid hipertrofi varlığı allerji deri testi, yaş, cinsiyet, tekrar eden alt veya üst solunum yolu enfeksiyonu öyküsü değerlendirilmiştir. Sonuçlar: 180 kız, 191 erkek olmak üzere 371 olgu (ortalama ± SD, 47±31 ay), çalışmaya dahil edilmiştir. Tekrar eden üst ve alt solunum yolu enfeksiyonu ile çinko düzeyleri (ortalama ± SD, 0,88±0,28), (ortalama ± SD, 0,88±0,35), arasında anlamlı ilişki saptanmamıştır. Tekrar eden solunum yolu enfeksiyonu olan olgular ile sağlıklı grup arasında, IgE düzeyleri açısından anlamlı istatistiksel fark bulunmamıştır (p=0,4). D vitamini düzeyleri tekrar eden alt ve üst solunum yolu enfeksiyonu olan grupta anlamlı olarak düşük bulunmuştur(p=0,001). Sonuç: Sağlıklı kontroller ile tekrar eden solunum yolu enfeksiyonu olan olgular arasında çinko düzeyleri açısından anlamlı fark saptanmamıştır. Tekrar eden solunum yolu enfeksiyonunda çinko suplementasyonu ancak eksikliği saptanmış olgulara önerilebilir, ve bu olgular tekrar eden solunum yolu enfeksiyonunda bağımsız risk faktörü olan adenoid hipertrofi varlığı açısından değerlendirilmelidir.

Anahtar Kelimeler

• Çinko, solunum, çocuk

Çocuklarda Çinko Düzeyleri İle Tekrar Eden Solunum Yolu Enfeksiyonu Arasında İlişki Var Mıdır?

Öz

Objective: There are many consequences connected with an inadequate intake of trace elements and Vitamin D. Allergic disorders and a susceptibility to respiratory infections may be related to deficiencies of trace elements and/or vitamin D. This cross-sectional study aims to investigate associations between recurrent respiratory system infections and Zinc levels; as well as other dependent factors. Methods: Three hundred and seventy one children living in Turkey were enrolled in the study between 2015 and 2017. Two hundred and forty nine had a history of either recurrent upper respiratory infections such as, acute otitis media, pharyngitis, rhinitis, or lower respiratory tract infections. 122 were considered as healthy controls. Age, gender, existence of adenoid hypertrophy, upper and lower respiratory tract infections, zinc levels, vitamin D levels, IgE levels, and a skin prick test were all evaluated. Results: A total of 371 children (mean age ± standard deviation = 47±31 months), 180 males and 191 females were included. No significant difference between the zinc levels of children with recurrent upper (mean ± standard deviation = 0,88±0,28) respiratory tract infections and lower respiratory tract (mean ±standard deviation= 0,88±0,35) infections was observed. Likewise, there was no significant difference between IgE levels of children with recurrent respiratory tract infections and healthy controls (p=0,4). Vitamin D levels, however, were found to be significantly lower in children with lower and upper respiratory tract infections (p=0,001). Conclusion: There was no significant difference in zinc levels between healthy controls and children with recurrent respiratory tract infections. However, if there is a documented low zinc deficiency, children with recurrent respiratory tract infections may be recommended a zinc supplementation protocol. Additionally, these children should also be monitored for adenoid hypertrophy; an independent risk factor for recurrent respiratory tract infections.

Anahtar Kelimeler

• Zinc, Respiratory, Child

Kaynakça

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