MELISSA OFFICINALIS (OĞUL OTU)’İN GELENEKSEL KULLANIMI

Yıl 2017, Cilt: 26 Sayı: 3, 267 - 269, 01.12.2017

Gamze Başkal Esra Köngül Gökçe Şeker Karatoprak

Öz

İlk çağlardan itibaren insanlar beslenmek ve sağlık sorunlarını gidermek amacıyla bitkilere başvurmuşlardır.
Mitolojide de bitkiler tanrıların insana verdiği en değerli armağan olarak ele alınmıştır. Mitolojiden günümüze
uzun bir hikayesi olan Melissa officinalis (Oğulotu, Melisa) bir Akdeniz bitkisi olup, yurdumuzda da yetişen çok
yıllık otsu bir türdür. Dioscorides, İbn-i Sina, Paracelsus
ve John Evelyn tarafından çeşitli hastalıkların tedavisinde bitkisel ilaç olarak kullanılmıştır. Günümüzde ise
özellikle yatıştırıcı, midevi, gaz söktürücü, terletici ve
antiseptik etkilerinden dolayı kullanımı bulunmaktadır.

Anahtar Kelimeler

Melissa officinalis, geleneksel kullanım, oğulotu

Traditional Usage of Melıssa Officinalis

Öz

From the early ages people have resorted to the plants
to get nutrition and solve health problems. In
mythology, plants are considered to be the most
valuable gift that gods have given to human. Melissa
officinalis (balm, melisa) which has a long-time story of
in mythology, is a mediterranean herb and is a
perennial herbaceous species that grows in our country.
It has been used by Dioscorides, Avicenna, Paracelsus
and John Evelyn as herbal medicines in the treatment of
various diseases. Today, it is used especially because of
sedative, gastric, antitussive, diaphoretic and antiseptic
effects.

Anahtar Kelimeler

Melissa officinalis, traditional usage, lemonbalm

Kaynakça

• 1. Mill RR. Melissa L. In: Davis PH (ed) Flora of Turkey and the East Aegean Islands, Vol. 7. Edinburgh University Press, Edinburgh 1982; pp 262-264.
• 2. Hedge IC. A global survey of the biogeography of the Labiatae. In: Harleyand RM, Reynolds T (eds), Advances in Labiatae Science. Royal Botanic Gardens, Kew 1992; pp 7-17.
• 3. Baytop T. Türkiye’de Bitkiler İle Tedavi, Geçmişte ve Bugün (2nd ed). Nobel Tıp Kitapevleri, İstanbul 1999; ss 550.
• 4. Ceylan A. Tıbbi Bitkiler-II (Uçucu Yağ İçerenler). Ege Üniv. Ziraat Fakültesi Yayın No:481, Ders Kitabı 1997; ss 306.
• 5. Charles DJ. Lemon Balm. In: Charles DJ (eds), Antioxidant Properties of Spices, Herbs and Other Sources. Springer, Norway, IA, USA 2013; pp 371- 376.
• 6. Blumenthal M, Riggins CW. Popular herbs in the U.S. market: Therapeutic monographs. American Botanical Council, Austin, TX, 1997.
• 7. Osbaldeston TA. Dioscorides. Ibıdıs Press, Johannesburg South Africa 2000; pp 503.
• 8. Kâhya E. İbn-i Sina El-Kanun Fi’t-Tıbb, İkinci kitap (1st ed). Atatürk Kültür Merkezi Yayını, Ankara 2003; ss 138.
• 9. Kennedy DO, Scholey AB, Tildesley NTJ, Perry EK, Wesnes KA. Modulation of mood and cognitive performance following acute administration of Melissa officinalis (lemonbalm). Pharmacol Biochem Behav 2002; 72:953-964.
• 10. Johnson RL, Foster S, Dog TL, Kiefer D. National Geographic guide to medicinal herbs: The world’s most effective healing plants. National Geographic, Washington D.C. 2010; pp 14-34.
• 11. Shakeri A, Sahebkar A, Javadi B. Melissa officinalis L. A review of its traditional uses, phytochemistry and pharmacology. J Ethnopharmacol 2016; 188:204-228.
• 12. Taherpour A, Maroofi H, Rafie Z, Larijani K. Chemical composition analysis of the essential oil of Melissa officinalis L. from Kurdistan, Iran by HS/ SPME method and calculation of the biophysicochemical coefficients of the components. Nat Prod Res 2012; 26:152-160.
• 13. Baytop T. Türkçe bitki adları sözlüğü. Türk Dil Kurumu, Öncü Basımevi, Ankara 2007; ss: 217.
• 14. Şaşkara C, Hürkul MM, Güvenç A. Aktarlarda satılan Melissa offıcinalis L.(Oğulotu, Melisa) üzerinde morfolojik ve anatomik çalışmalar. Ankara Ecz Fak Derg 2010; 39:123-143.
• 15. Tuzlacı E. Türkiye’nin Bitkisel Halk İlaçları, Alfa Basımevi, İstanbul 2006; ss: 195-198.
• 16. Sarı AO, Oğuz B, Bilgiç A, Tort N, Güvensen A, Şenol SG. Ege ve Güney Marmara bölgelerinde halk ilacı olarak kullanılan bitkiler. J of AARI 2010; 20:1-21.
• 17. Kalankan G, Özkan ZC, Akbulut S. Medicinal and aromatic wild plants and traditional usage of them in Mount Ida (Balıkesir/Turkey). JABS 2015; 9:25- 33.
• 18. Leblebici S, Bahtiyar SD, Özyurt MS. Kütahya aktarlarında satılan bazı tıbbi bitkilerin ağır metal miktarlarının incelenmesi. DPÜ Fen Bilimleri Enstitüsü Dergisi 2012; 29:1-6.
• 19. Kennedy DO, Wake G, Savelev S, et al. Modulation of mood and cognitive performance following acute administration of single doses of Melissa officinalis (Lemon balm) with human CNS nicotinic and muscarinic receptor-binding properties. Neuropsychopharmacol 2003; 28:1871 -1881.
• 20. Cases J, Ibarra A, Feuillere N, Roller M, Sukkar SG. Pilot trial of Melissa officinalis L. leaf extract in the treatment of volunteers suffering from mild-tomoderate anxiety disorders and sleep disturbances. Med J Nutrition Metab 2011; 4:211- 218.
• 21. Akhondzadeh S, Noroozian M, Mohammadi M, et al. Melissa officinalis extract in the treatment of patients with mild to moderate Alzheimer’s disease: a double blind, randomised, placebo controlled trial. J Neurol Neurosurg Psychiatry 2003; 74:863-866.
• 22. Ballard CG, O'Brien JT, Reichelt K, Perry EK. Aromatherapy as a safe and effective treatment for the management of agitation in severe dementia: the results of a double-blind, placebo-controlled trial with Melissa. J Clin Psychiatry 2002; 63:553- 558.
• 23. Zeraatpishe A, Oryan S, Bagheri MH, et al. Effects of Melissa officinalis L. on oxidative status and DNA damage in subjects exposed to long-term low-dose ionizing radiation. Toxicol Ind Health, 2011; 27:205-212.
• 24. Alijaniha F, Naseri M, Afsharypuor S, et al. Heart palpitation relief with Melissa officinalis leaf extract: double blind, randomized, placebo controlled trial of efficacy and safety. J Ethnopharmacol 2015; 164:378-384.
• 25. Safdari-Dehcheshmehi F, Parvin N. The effect of mefenamic acid and Melissa officinalis on primary dysmenorrhea: A randomized clinical trial study. IJPPR 2016; 8:1286-1292.
• 26. Hasanein P, Riahi H. Antinociceptive and antihyperglycemic effects of Melissa officinalis essential oil in an experimental model of diabetes. Med Princ Pract 2015; 24:47-52.
• 27. Bounihi A, Hajjaj G, Alnamer R, Cherrah Y, Zellou A. In vivo potential anti-inflammatory activity of Melissa officinalis L. essential oil. Adv Pharmacol Sci 2013; doi: 10.1155/2013/101759.
• 28. Birdane YO, Buyukokuroglu ME, Birdane FM, Cemek M, Yavuz H. Anti-inflammatory and antinociceptive effects of Melissa officinalis L. in rodents. Rev Med Vet 2007; 158:75-81.
• 29. Bahtiyarca Bağdat R, Coşge B. The essential oil of lemon balm (Melissa officinalis L.), its components and using fields. J of Fac of Agric 2006; 21:116- 121.
• 30. Baykan Erel Ş. Melissa officinalis L. In: Demirezer Ö, Ersöz T, Saraçoğlu D, Şener B (Eds.), FFD Monografları “Tedavide Kullanılan Bitkiler” (2nd ed). MN Medical & Nobel Tıp Kitabevi, Ankara 2011; ss: 383- 390.