Araştırma Makalesi
BibTex RIS Kaynak Göster

Yıl 2026, Cilt: 41 Sayı: 1 , 519 - 532 , 31.03.2026
https://doi.org/10.17341/gazimmfd.1631531
https://izlik.org/JA34AJ64PG

Öz

Kaynakça

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Aktivasyon fonksiyonları ve derin öğrenme mimarilerinin beyin MRI görüntüleri üzerindeki sınıflandırma performanslarının incelenmesi

Yıl 2026, Cilt: 41 Sayı: 1 , 519 - 532 , 31.03.2026
https://doi.org/10.17341/gazimmfd.1631531
https://izlik.org/JA34AJ64PG

Öz

Beyin tümörü tespiti, tıbbi görüntüleme alanında en kritik süreçlerden biri olup, manyetik rezonans görüntüleme (MRI) yüksek çözünürlüklü yumuşak doku detayları sayesinde tanı sürecinde önemli bir rol oynamaktadır. Ancak MRI görüntülerinin manuel olarak değerlendirilmesi zaman alıcı ve hataya açık bir süreçtir. Bu nedenle, derin öğrenme tabanlı otomatik sistemlerin geliştirilmesi, tanı hızını artırmak ve sağlık hizmetlerinin etkinliğini yükseltmek açısından büyük önem taşımaktadır. Bu çalışmada, Brain MRI görüntülerinden oluşan bir veri seti kullanılarak beyin tümörlerinin sınıflandırılması amaçlanmıştır. Öncelikle, veri setine görüntü işleme teknikleri uygulanarak iyileştirilmiş görüntüler elde edilmiştir. Ardından, orijinal ve iyileştirilmiş görüntüler yedi farklı transfer öğrenme mimarisine girdi olarak verilmiştir. Sonuçlar, tüm modellerde iyileştirilmiş görüntülerin daha yüksek doğruluk sağladığını göstermiştir. Çalışmanın ikinci aşamasında, en başarılı iki model olan ResNet101 ve ResNet152 üzerinde farklı aktivasyon fonksiyonları test edilmiştir. Önerilen hibrit aktivasyon fonksiyonu ile ResNet101 %98,42, ResNet152 ise %97,20 doğruluk oranına ulaşarak en yüksek performansı göstermiştir. Bu bulgular, önerilen yöntemin sınıflandırma başarısını önemli ölçüde artırdığını ortaya koymaktadır.

Etik Beyan

Bu çalışmada kullanılan tüm veri setleri, halka açık ve ücretsiz erişime sahip olan veri kaynaklarından temin edilmiştir. Veri setleri, belirli etik kurallar ve gizlilik ilkelerine uygun olarak sağlanmış ve hiçbir kişisel bilgi içermemektedir. Çalışma, veri sahiplerinin onaylarını ve ilgili yasal düzenlemeleri göz önünde bulundurarak gerçekleştirilmiştir. Kullanılan veri setleri, yalnızca akademik amaçlarla ve araştırma bağlamında kullanılmıştır. Bu araştırmada herhangi bir etik ihlal bulunmamaktadır.

Kaynakça

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  • 2. Olanow C.W., Hauser R.A., Magnetic Resonance Imaging in Neurodegenerative Diseases, Neurodegenerative Diseases, 445–469, 1994.
  • 3. Litjens G., Kooi T., Bejnordi B.E., Setio A.A.A., Ciompi F., Ghafoorian M., Sánchez C.I., A Survey on Deep Learning in Medical Image Analysis, Medical Image Analysis, 42, 60–88, 2017.
  • 4. LeCun Y., Bengio Y., Hinton G., Deep Learning, Nature, 521(7553), 436–444, 2015.
  • 5. Patel S., Bharath K.P., Balaji S., Muthu R.K., Comparative Study on Histogram Equalization Techniques for Medical Image Enhancement, Soft Computing for Problem Solving, 1, 657–669, 2018.
  • 6. Jähne B., Digital Image Processing, Springer Science & Business Media, Berlin, Germany, 2005.
  • 7. Rajinikanth V., Priya E., Lin H., Lin F., Hybrid Image Processing Methods for Medical Image Examination, CRC Press, Boca Raton, USA, 2021.
  • 8. LeCun Y., Bottou L., Bengio Y., Haffner P., Gradient-Based Learning Applied to Document Recognition, Proceedings of the IEEE, 86(11), 2278–2324, 1998.
  • 9. Kamnitsas K., Ledig C., Newcombe V.F., Simpson J.P., Kane A.D., Menon D.K., Glocker B., Efficient Multi-Scale 3D CNN with Fully Connected CRF for Accurate Brain Lesion Segmentation, Medical Image Analysis, 36, 61–78, 2017.
  • 10. Peng S., Chen W., Sun J., Liu B., Multi-Scale 3D U-Nets: An Approach to Automatic Segmentation of Brain Tumor, International Journal of Imaging Systems and Technology, 30(1), 5–17, 2020.
  • 11. Nazir M., Wahid F., Ali Khan S., A Simple and Intelligent Approach for Brain MRI Classification, Journal of Intelligent & Fuzzy Systems, 28(3), 1127–1135, 2015.
  • 12. Korolev S., Safiullin A., Belyaev M., Dodonova Y., Residual and Plain Convolutional Neural Networks for 3D Brain MRI Classification, IEEE ISBI, Washington DC, USA, 835–838, April 2017.
  • 13. Zhang Y., Dong Z., Wu L., Wang S., A Hybrid Method for MRI Brain Image Classification, Expert Systems with Applications, 38(8), 10049–10053, 2011.
  • 14. Assam M., Kanwal H., Farooq U., Shah S.K., Mehmood A., Choi G.S., An Efficient Classification of MRI Brain Images, IEEE Access, 9, 33313–33322, 2021.
  • 15. Fayaz M., Torokeldiev N., Turdumamatov S., Qureshi M.S., Qureshi M.B., Gwak J., An Efficient Methodology for Brain MRI Classification Based on DWT and Convolutional Neural Network, Sensors, 21(22), 7480, 2021.
  • 16. Badža M.M., Barjaktarović M.Č., Classification of Brain Tumors from MRI Images Using a Convolutional Neural Network, Applied Sciences, 10(6), 1999, 2020.
  • 17. Abiwinanda N., Hanif M., Hesaputra S.T., Handayani A., Mengko T.R., Brain Tumor Classification Using Convolutional Neural Network, World Congress on Medical Physics and Biomedical Engineering, 183–189, 2019.
  • 18. Vankdothu R., Hameed M.A., Brain Tumor MRI Images Identification and Classification Based on the Recurrent Convolutional Neural Network, Measurement: Sensors, 24, 100412, 2022.
  • 19. Chelghoum R., Ikhlef A., Hameurlaine A., Jacquir S., Transfer Learning Using Convolutional Neural Network Architectures for Brain Tumor Classification from MRI Images, IFIP International Conference on Artificial Intelligence Applications and Innovations, 189–200, 2020.
  • 20. Çinar A., Yildirim M., Detection of Tumors on Brain MRI Images Using the Hybrid Convolutional Neural Network Architecture, Medical Hypotheses, 139, 109684, 2020.
  • 21. Yazdan S.A., Ahmad R., Iqbal N., Rizwan A., Khan A.N., Kim D.H., An Efficient Multi-Scale Convolutional Neural Network Based Multi-Class Brain MRI Classification for SaMD, Tomography, 8(4), 1905–1927, 2022.
  • 22. Toğaçar M., Cömert Z., Ergen B., Classification of Brain MRI Using Hyper Column Technique with Convolutional Neural Network and Feature Selection Method, Expert Systems with Applications, 149, 113274, 2020.
  • 23. Jibon F.A., Khandaker M.U., Miraz M.H., Thakur H., Rabby F., Tamam N., Osman H., Cancerous and Non-Cancerous Brain MRI Classification Method Based on Convolutional Neural Network and Log-Polar Transformation, Healthcare, 10(9), 1801, 2022.
  • 24. Abd El Kader I., Xu G., Shuai Z., Saminu S., Javaid I., Salim Ahmad I., Differential Deep Convolutional Neural Network Model for Brain Tumor Classification, Brain Sciences, 11(3), 352, 2021.
  • 25. Mzoughi H., Njeh I., Wali A., Slima M.B., BenHamida A., Mhiri C., Mahfoudhe K.B., Deep Multi-Scale 3D Convolutional Neural Network (CNN) for MRI Gliomas Brain Tumor Classification, Journal of Digital Imaging, 33, 903–915, 2020.
  • 26. Musallam A.S., Sherif A.S., Hussein M.K., A New Convolutional Neural Network Architecture for Automatic Detection of Brain Tumors in Magnetic Resonance Imaging Images, IEEE Access, 10, 2775–2782, 2022.
  • 27. Remzan N., Tahiry K., Farchi A., Brain Tumor Classification in Magnetic Resonance Imaging Images Using Convolutional Neural Network, International Journal of Electrical and Computer Engineering, 12(6), 6664–6672, 2022.
  • 28. Talo M., Yildirim O., Baloglu U.B., Aydin G., Acharya U.R., Convolutional Neural Networks for Multi-Class Brain Disease Detection Using MRI Images, Computerized Medical Imaging and Graphics, 78, 101673, 2019.
  • 29. Rahman T., Islam M.S., MRI Brain Tumor Detection and Classification Using Parallel Deep Convolutional Neural Networks, Measurement: Sensors, 26, 100694, 2023.
  • 30. Choudhuri R., Halder A., Brain MRI Tumour Classification Using Quantum Classical Convolutional Neural Net Architecture, Neural Computing and Applications, 35(6), 4467–4478, 2023.
  • 31. Hazarika R.A., Maji A.K., Kandar D., Jasinska E., Krejci P., Leonowicz Z., Jasinski M., An Approach for Classification of Alzheimer’s Disease Using Deep Neural Network and Brain Magnetic Resonance Imaging (MRI), Electronics, 12(3), 676, 2023.
  • 32. Rahman T., Islam M.S., MRI Brain Tumor Classification Using Deep Convolutional Neural Network, International Conference on Innovations in Science, Engineering and Technology, 451–456, 2022.
  • 33. Choudhury C.L., Mahanty C., Kumar R., Mishra B.K., Brain Tumor Detection and Classification Using Convolutional Neural Network and Deep Neural Network, International Conference on Computer Science, Engineering and Applications, 1–4, 2020.
  • 34. Shen D., Wu G., Suk H.I., Deep Learning in Medical Image Analysis, Annual Review of Biomedical Engineering, 19(1), 221–248, 2017.
  • 35. Razzak M.I., Naz S., Zaib A., Deep Learning for Medical Image Processing: Overview, Challenges and the Future, Classification in BioApps: Automation of Decision Making, 323–350, 2018.
  • 36. Nickparvar M., Brain Tumor MRI Dataset, Kaggle, https://www.kaggle.com/datasets/masoudnickparvar/brain-tumor-mri-dataset, Erişim Tarihi: 25.02.2026.
  • 37. Esteva A., Robicquet A., Ramsundar B., Kuleshov V., DePristo M., Chou K., Dean J., A Guide to Deep Learning in Healthcare, Nature Medicine, 25(1), 24–29, 2019.
  • 38. Akkus Z., Galimzianova A., Hoogi A., Rubin D.L., Erickson B.J., Deep Learning for Brain MRI Segmentation: State of the Art and Future Directions, Journal of Digital Imaging, 30, 449–459, 2017.
  • 39. Shaheen F., Verma B., Asafuddoula M., Impact of Automatic Feature Extraction in Deep Learning Architecture, International Conference on Digital Image Computing: Techniques and Applications, 1–8, 2016.
  • 40. Wang S., Peng Y., Lu L., Lu Z., Bagheri M., Summers R.M., Deep Learning in Medical Image Analysis: A Review, Current Imaging and Labeling Systems, 14, 1449–1474, 2019.
  • 41. Yu X., Wang J., Hong Q.Q., Teku R., Wang S.H., Zhang Y.D., Transfer Learning for Medical Images Analyses: A Survey, Neurocomputing, 489, 230–254, 2022.
  • 42. Krizhevsky A., Sutskever I., Hinton G.E., Imagenet Classification with Deep Convolutional Neural Networks, Advances in Neural Information Processing Systems, 25, 1–9, 2012.
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Toplam 83 adet kaynakça vardır.

Ayrıntılar

Birincil Dil Türkçe
Konular Derin Öğrenme, Nöral Ağlar
Bölüm Araştırma Makalesi
Yazarlar

Yasin Özkan 0000-0002-2029-0856

Gönderilme Tarihi 2 Şubat 2025
Kabul Tarihi 16 Ocak 2026
Yayımlanma Tarihi 31 Mart 2026
DOI https://doi.org/10.17341/gazimmfd.1631531
IZ https://izlik.org/JA34AJ64PG
Yayımlandığı Sayı Yıl 2026 Cilt: 41 Sayı: 1

Kaynak Göster

APA Özkan, Y. (2026). Aktivasyon fonksiyonları ve derin öğrenme mimarilerinin beyin MRI görüntüleri üzerindeki sınıflandırma performanslarının incelenmesi. Gazi Üniversitesi Mühendislik Mimarlık Fakültesi Dergisi, 41(1), 519-532. https://doi.org/10.17341/gazimmfd.1631531
AMA 1.Özkan Y. Aktivasyon fonksiyonları ve derin öğrenme mimarilerinin beyin MRI görüntüleri üzerindeki sınıflandırma performanslarının incelenmesi. GUMMFD. 2026;41(1):519-532. doi:10.17341/gazimmfd.1631531
Chicago Özkan, Yasin. 2026. “Aktivasyon fonksiyonları ve derin öğrenme mimarilerinin beyin MRI görüntüleri üzerindeki sınıflandırma performanslarının incelenmesi”. Gazi Üniversitesi Mühendislik Mimarlık Fakültesi Dergisi 41 (1): 519-32. https://doi.org/10.17341/gazimmfd.1631531.
EndNote Özkan Y (01 Mart 2026) Aktivasyon fonksiyonları ve derin öğrenme mimarilerinin beyin MRI görüntüleri üzerindeki sınıflandırma performanslarının incelenmesi. Gazi Üniversitesi Mühendislik Mimarlık Fakültesi Dergisi 41 1 519–532.
IEEE [1]Y. Özkan, “Aktivasyon fonksiyonları ve derin öğrenme mimarilerinin beyin MRI görüntüleri üzerindeki sınıflandırma performanslarının incelenmesi”, GUMMFD, c. 41, sy 1, ss. 519–532, Mar. 2026, doi: 10.17341/gazimmfd.1631531.
ISNAD Özkan, Yasin. “Aktivasyon fonksiyonları ve derin öğrenme mimarilerinin beyin MRI görüntüleri üzerindeki sınıflandırma performanslarının incelenmesi”. Gazi Üniversitesi Mühendislik Mimarlık Fakültesi Dergisi 41/1 (01 Mart 2026): 519-532. https://doi.org/10.17341/gazimmfd.1631531.
JAMA 1.Özkan Y. Aktivasyon fonksiyonları ve derin öğrenme mimarilerinin beyin MRI görüntüleri üzerindeki sınıflandırma performanslarının incelenmesi. GUMMFD. 2026;41:519–532.
MLA Özkan, Yasin. “Aktivasyon fonksiyonları ve derin öğrenme mimarilerinin beyin MRI görüntüleri üzerindeki sınıflandırma performanslarının incelenmesi”. Gazi Üniversitesi Mühendislik Mimarlık Fakültesi Dergisi, c. 41, sy 1, Mart 2026, ss. 519-32, doi:10.17341/gazimmfd.1631531.
Vancouver 1.Yasin Özkan. Aktivasyon fonksiyonları ve derin öğrenme mimarilerinin beyin MRI görüntüleri üzerindeki sınıflandırma performanslarının incelenmesi. GUMMFD. 01 Mart 2026;41(1):519-32. doi:10.17341/gazimmfd.1631531