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Histopathological Diagnosis Transformed Into Clinical Diagnosis Inverted Follicular Keratosis, Case Report

Cilt: 36 Sayı: 2026 13 Nisan 2026
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Histopathological Diagnosis Transformed Into Clinical Diagnosis Inverted Follicular Keratosis, Case Report

Öz

Inverted follicular keratosis (IFK) is a rare benign tumor characterized by endophytic proliferation originating from the infundibulum of the hair follicle (1,2). Although not frequently encountered, we believe that inverted follicular keratosis should be considered a distinct entity to keep in mind due to its potential to be confused with conditions such as verruca vulgaris, seborrheic keratosis, actinic keratosis, keratoacanthoma, basal cell carcinoma, and squamous cell carcinoma.

Anahtar Kelimeler

Actinic changes, Follicular keratosis, Histopathology

Kaynakça

  1. 1-Heriyanto DS, Lau V, Phang V. Two distinct lesions of inverted follicular keratosis of the scalp: A case report. Cureus. 2022 Nov;3;14(11). doi: 10.7759/cureus.31055.
  2. 2-Zaballos P, Gómez-Martín I, Martín JM, Bañuls J. Dermoscopy of adnexal tumors. Dermatol Clin. 2018 Oct;36(4):397-412. doi: 10.1016/j.det.2018.05.007.
  3. 3-Karadag AS, Ozlu E, Uzuncakmak TK, Akdeniz N, Cobanoglu B, Oman B. Inverted follicular keratosis successfully treated with imiquimod. Indian Dermatol Online J. 2016;7(3):177-179. doi: 10.4103/2229-5178.182354.
  4. 4-Armengot-Carbo M, Abrego A, Gonzalez T, Alarcon I, Alos L, Carrera C, Malvehy J, Puig S. Inverted follicular keratosis: Dermoscopic and reflectance confocal microscopic features. Dermatology. 2013;227(1):62-6. doi: 10.1159/000351715.
  5. 5-Spielvogel RL, Austin C, Ackerman AB. Inverted follicular keratosis is not a specific keratosis but a verruca vulgaris (or seborrheic keratosis) with squamous eddies. Am J Dermatopathol. 1983;5(5):427–42. doi: 10.1097/00000372-198310000-00003.
  6. 6- Thom GA, Quirk CJ, Heenan PJ. Inverted follicular keratosis simulating malignant melanoma. Australas J Dermatol. 2004;45(1):55–7. doi: 10.1111/j.1440-0960.2004.00032.x.
  7. 7- Ruhoy SM, Thomas D, Nuovo GJ. Multiple inverted follicular keratoses as a presenting sign of Cowden's syndrome: Case report with human papillomavirus studies. J Am Acad Dermatol. 2004;51(3):411–5. doi: 10.1016/j.jaad.2003.12.049.
  8. 8- Baklouti M, Sellami K, Mellouli M, Rekik M, Chaabouni R, Masmoudi A, Sellami T, Turki H. Inverted Follicular Keratosis: A Retrospective Study Over 10 Years. Indian J Dermatol. 2023;68(1):122.doi: 10.4103/ijd.ijd_968_21.
  9. 9-Ray A, Panda M, Samant S, Mohanty P. A rare case of inverted follicular keratosis in an elderly male: Dermoscopic and histopathological overview with therapeutic response to imiquimod. Indian J Dermatol Venereol Leprol. 2021;87(3);455. doi: 10.25259/IJDVL_224_20.

Kaynak Göster

APA
Gökkaya, G., Pektaş, Ö. E., Celik, M., & Yavuz, C. (2026). Histopathological Diagnosis Transformed Into Clinical Diagnosis Inverted Follicular Keratosis, Case Report. Genel Tıp Dergisi, 36(2026), 1-3. https://doi.org/10.54005/geneltip.1667395
AMA
1.Gökkaya G, Pektaş ÖE, Celik M, Yavuz C. Histopathological Diagnosis Transformed Into Clinical Diagnosis Inverted Follicular Keratosis, Case Report. Genel Tıp Derg. 2026;36(2026):1-3. doi:10.54005/geneltip.1667395
Chicago
Gökkaya, Gamze, Ömer Erkam Pektaş, Murat Celik, ve Cahit Yavuz. 2026. “Histopathological Diagnosis Transformed Into Clinical Diagnosis Inverted Follicular Keratosis, Case Report”. Genel Tıp Dergisi 36 (2026): 1-3. https://doi.org/10.54005/geneltip.1667395.
EndNote
Gökkaya G, Pektaş ÖE, Celik M, Yavuz C (01 Nisan 2026) Histopathological Diagnosis Transformed Into Clinical Diagnosis Inverted Follicular Keratosis, Case Report. Genel Tıp Dergisi 36 2026 1–3.
IEEE
[1]G. Gökkaya, Ö. E. Pektaş, M. Celik, ve C. Yavuz, “Histopathological Diagnosis Transformed Into Clinical Diagnosis Inverted Follicular Keratosis, Case Report”, Genel Tıp Derg, c. 36, sy 2026, ss. 1–3, Nis. 2026, doi: 10.54005/geneltip.1667395.
ISNAD
Gökkaya, Gamze - Pektaş, Ömer Erkam - Celik, Murat - Yavuz, Cahit. “Histopathological Diagnosis Transformed Into Clinical Diagnosis Inverted Follicular Keratosis, Case Report”. Genel Tıp Dergisi 36/2026 (01 Nisan 2026): 1-3. https://doi.org/10.54005/geneltip.1667395.
JAMA
1.Gökkaya G, Pektaş ÖE, Celik M, Yavuz C. Histopathological Diagnosis Transformed Into Clinical Diagnosis Inverted Follicular Keratosis, Case Report. Genel Tıp Derg. 2026;36:1–3.
MLA
Gökkaya, Gamze, vd. “Histopathological Diagnosis Transformed Into Clinical Diagnosis Inverted Follicular Keratosis, Case Report”. Genel Tıp Dergisi, c. 36, sy 2026, Nisan 2026, ss. 1-3, doi:10.54005/geneltip.1667395.
Vancouver
1.Gamze Gökkaya, Ömer Erkam Pektaş, Murat Celik, Cahit Yavuz. Histopathological Diagnosis Transformed Into Clinical Diagnosis Inverted Follicular Keratosis, Case Report. Genel Tıp Derg. 01 Nisan 2026;36(2026):1-3. doi:10.54005/geneltip.1667395