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Has the COVID-19 Pandemic Affected the Clinical Severity and Incidence of Inflammatory Bowel Disease in Children?

Cilt: 36 Sayı: 2026 4 Şubat 2026
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Has the COVID-19 Pandemic Affected the Clinical Severity and Incidence of Inflammatory Bowel Disease in Children?

Öz

Aims:It is known that SARS-CoV-2 enters the body by binding to angiotensin-converting enzyme-2 (ACE-2) receptors. Given that the gastrointestinal tract is rich in ACE-2 receptors, we hypothesized that SARS-CoV-2 may have increased the frequency, disease activation, and clinical presentation of inflammatory bowel disease (IBD). Methods: The study was conducted in two phases, each spanning a duration of three years. The first phase corresponded to the pre-pandemic period, which spanned from January 2017 to February 2020. The second phase encompassed the pandemic period from February 2020 to January 2023. The IBD diagnoses were recorded in 25 patients in the pre-pandemic period and 41 patients in the pandemic period, retrospectively. Results:The ratio of the number of patients admitted to the outpatient clinic and the number of procedures performed was significantly higher in the pre-pandemic and pandemic periods (17.53% vs. 25.81%, p<0.001). However, the ratio of patients diagnosed with IBD and the number of procedures performed exhibited a significantly higher value during the pandemic period compared to the pre-pandemic period (1.76% vs. 3%, p<0.001). C-reactive protein (CRP) level of the patients included in the study in the pandemic period was significantly higher compared to the pre-pandemic period (2.95 vs. 50, p<0.001). Conclusions:The present study has revealed that the prevalence of IBD has increased in children during the course of the ongoing pandemic of the novel coronavirus, SARS-CoV-2, also known as "COVID-19." It is therefore recommended that children presenting with gastrointestinal tract complaints and possible cases of SARS-CoV-2 infection undergo evaluation for IBD.

Anahtar Kelimeler

Crohn, inflammatory bowel disease, SARS-CoV-2, ulcerative colitis.

Destekleyen Kurum

None

Etik Beyan

The study was granted permission from the Ethics Committee of Selçuk University Faculty of Medicine (number 2023/219; date: April 25, 2023).

Kaynakça

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Kaynak Göster

APA
Ergani, A. C., Aydin, V. B., Abidin, İ., Ağır, M. A., Körez, M. K., Gümüş, M., & Emiroğlu, H. H. (2026). Has the COVID-19 Pandemic Affected the Clinical Severity and Incidence of Inflammatory Bowel Disease in Children? Genel Tıp Dergisi, 36(2026), 1-5. https://doi.org/10.54005/geneltip.1744234
AMA
1.Ergani AC, Aydin VB, Abidin İ, vd. Has the COVID-19 Pandemic Affected the Clinical Severity and Incidence of Inflammatory Bowel Disease in Children? Genel Tıp Derg. 2026;36(2026):1-5. doi:10.54005/geneltip.1744234
Chicago
Ergani, Anna Carina, Vesile Betül Aydin, İlhan Abidin, vd. 2026. “Has the COVID-19 Pandemic Affected the Clinical Severity and Incidence of Inflammatory Bowel Disease in Children?”. Genel Tıp Dergisi 36 (2026): 1-5. https://doi.org/10.54005/geneltip.1744234.
EndNote
Ergani AC, Aydin VB, Abidin İ, Ağır MA, Körez MK, Gümüş M, Emiroğlu HH (01 Şubat 2026) Has the COVID-19 Pandemic Affected the Clinical Severity and Incidence of Inflammatory Bowel Disease in Children? Genel Tıp Dergisi 36 2026 1–5.
IEEE
[1]A. C. Ergani vd., “Has the COVID-19 Pandemic Affected the Clinical Severity and Incidence of Inflammatory Bowel Disease in Children?”, Genel Tıp Derg, c. 36, sy 2026, ss. 1–5, Şub. 2026, doi: 10.54005/geneltip.1744234.
ISNAD
Ergani, Anna Carina - Aydin, Vesile Betül - Abidin, İlhan - Ağır, Mehmet Akif - Körez, Muslu Kazım - Gümüş, Meltem - Emiroğlu, Halil Haldun. “Has the COVID-19 Pandemic Affected the Clinical Severity and Incidence of Inflammatory Bowel Disease in Children?”. Genel Tıp Dergisi 36/2026 (01 Şubat 2026): 1-5. https://doi.org/10.54005/geneltip.1744234.
JAMA
1.Ergani AC, Aydin VB, Abidin İ, Ağır MA, Körez MK, Gümüş M, Emiroğlu HH. Has the COVID-19 Pandemic Affected the Clinical Severity and Incidence of Inflammatory Bowel Disease in Children? Genel Tıp Derg. 2026;36:1–5.
MLA
Ergani, Anna Carina, vd. “Has the COVID-19 Pandemic Affected the Clinical Severity and Incidence of Inflammatory Bowel Disease in Children?”. Genel Tıp Dergisi, c. 36, sy 2026, Şubat 2026, ss. 1-5, doi:10.54005/geneltip.1744234.
Vancouver
1.Anna Carina Ergani, Vesile Betül Aydin, İlhan Abidin, Mehmet Akif Ağır, Muslu Kazım Körez, Meltem Gümüş, Halil Haldun Emiroğlu. Has the COVID-19 Pandemic Affected the Clinical Severity and Incidence of Inflammatory Bowel Disease in Children? Genel Tıp Derg. 01 Şubat 2026;36(2026):1-5. doi:10.54005/geneltip.1744234