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Prognostic Value of TAPSE/sPAP Ratio, RV S′ Velocity, and RV S′/sPAP Ratio in Hospitalized Patients with COVID-19: A Retrospective Echocardiographic Analysis

Cilt: 36 Sayı: 2026 27 Mart 2026
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Prognostic Value of TAPSE/sPAP Ratio, RV S′ Velocity, and RV S′/sPAP Ratio in Hospitalized Patients with COVID-19: A Retrospective Echocardiographic Analysis

Öz

Aim: This study aimed to evaluate the association between the tricuspid annular plane systolic excursion (TAPSE) systolic pulmonary artery pressure (sPAP) ratio, right ventricular (RV) S′ velocity, RV S′/sPAP ratio and, adverse clinical outcomes in hospitalized COVID-19 patients.

Materials and Methods: A retrospective cohort of 100 adult patients hospitalized with laboratory-confirmed COVID-19 who underwent transthoracic echocardiography (TTE) was analyzed. Patients were classified into two groups according to clinical outcomes: adverse outcome (ICU admission, mechanical ventilation, ARDS, or in-hospital mortality) and favorable outcome. Echocardiographic parameters (TAPSE, sPAP, RV S′, TAPSE/sPAP, and RV S′/sPAP) were compared between groups, and receiver operating characteristic (ROC) curve analysis was performed to assess discriminative performance in this exploratory analysis.

Results: Thirty-two patients experienced adverse outcomes. The TAPSE/sPAP ratio (0.44 ± 0.18 vs. 0.55 ± 0.22, p = 0.006), RV S′ velocity (9.17 ± 2.1 cm/s vs. 10.54 ± 2.1 cm/s, p = 0.004), and RV S′/sPAP ratio (0.28 ± 0.10 vs. 0.33 ± 0.08, p = 0.008) were significantly lower in the adverse outcome group. ROC analysis showed fair discriminative performance for TAPSE/sPAP, RV S′, and RV S′/sPAP with AUCs of 0.686, 0.691, and 0.753, respectively.

Conclusion: TAPSE/sPAP, RV S′, and RV S′/sPAP are non-invasive echocardiographic markers associated with adverse outcomes in hospitalized COVID-19 patients. Their combined use may contribute to early risk stratification in an exploratory, hypothesis-generating context.

Anahtar Kelimeler

COVID-19, Echocardiography, Right ventricular function, Prognosis, TAPSE/sPAP, RV S′/sPAP

Destekleyen Kurum

N.A.

Proje Numarası

KAEK:535 22.07.2020

Etik Beyan

This research complies with all the relevant national regulations, institutional policies and is in accordance with the tenets of the Helsinki Declaration, and has been approved by the Akdeniz University Medical Faculty Ethical Committee, Akdeniz University (Approval Number: KAEK-535, Date: 22.07.2020).

Teşekkür

N.A.

Kaynakça

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Kaynak Göster

APA
Ülgen Kunak, A., & Kunak, T. (2026). Prognostic Value of TAPSE/sPAP Ratio, RV S′ Velocity, and RV S′/sPAP Ratio in Hospitalized Patients with COVID-19: A Retrospective Echocardiographic Analysis. Genel Tıp Dergisi, 36(2026), 1-6. https://doi.org/10.54005/geneltip.1807952
AMA
1.Ülgen Kunak A, Kunak T. Prognostic Value of TAPSE/sPAP Ratio, RV S′ Velocity, and RV S′/sPAP Ratio in Hospitalized Patients with COVID-19: A Retrospective Echocardiographic Analysis. Genel Tıp Derg. 2026;36(2026):1-6. doi:10.54005/geneltip.1807952
Chicago
Ülgen Kunak, Ayşegül, ve Tolga Kunak. 2026. “Prognostic Value of TAPSE/sPAP Ratio, RV S′ Velocity, and RV S′/sPAP Ratio in Hospitalized Patients with COVID-19: A Retrospective Echocardiographic Analysis”. Genel Tıp Dergisi 36 (2026): 1-6. https://doi.org/10.54005/geneltip.1807952.
EndNote
Ülgen Kunak A, Kunak T (01 Mart 2026) Prognostic Value of TAPSE/sPAP Ratio, RV S′ Velocity, and RV S′/sPAP Ratio in Hospitalized Patients with COVID-19: A Retrospective Echocardiographic Analysis. Genel Tıp Dergisi 36 2026 1–6.
IEEE
[1]A. Ülgen Kunak ve T. Kunak, “Prognostic Value of TAPSE/sPAP Ratio, RV S′ Velocity, and RV S′/sPAP Ratio in Hospitalized Patients with COVID-19: A Retrospective Echocardiographic Analysis”, Genel Tıp Derg, c. 36, sy 2026, ss. 1–6, Mar. 2026, doi: 10.54005/geneltip.1807952.
ISNAD
Ülgen Kunak, Ayşegül - Kunak, Tolga. “Prognostic Value of TAPSE/sPAP Ratio, RV S′ Velocity, and RV S′/sPAP Ratio in Hospitalized Patients with COVID-19: A Retrospective Echocardiographic Analysis”. Genel Tıp Dergisi 36/2026 (01 Mart 2026): 1-6. https://doi.org/10.54005/geneltip.1807952.
JAMA
1.Ülgen Kunak A, Kunak T. Prognostic Value of TAPSE/sPAP Ratio, RV S′ Velocity, and RV S′/sPAP Ratio in Hospitalized Patients with COVID-19: A Retrospective Echocardiographic Analysis. Genel Tıp Derg. 2026;36:1–6.
MLA
Ülgen Kunak, Ayşegül, ve Tolga Kunak. “Prognostic Value of TAPSE/sPAP Ratio, RV S′ Velocity, and RV S′/sPAP Ratio in Hospitalized Patients with COVID-19: A Retrospective Echocardiographic Analysis”. Genel Tıp Dergisi, c. 36, sy 2026, Mart 2026, ss. 1-6, doi:10.54005/geneltip.1807952.
Vancouver
1.Ayşegül Ülgen Kunak, Tolga Kunak. Prognostic Value of TAPSE/sPAP Ratio, RV S′ Velocity, and RV S′/sPAP Ratio in Hospitalized Patients with COVID-19: A Retrospective Echocardiographic Analysis. Genel Tıp Derg. 01 Mart 2026;36(2026):1-6. doi:10.54005/geneltip.1807952