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Investigation on families have autistic children about knowladge level of vaccines, vaccination denial frequency, and reasons of vaccinaiton denial in different regions of Turkey.

Yıl 2021, Cilt: 31 Sayı: 3, 225 - 231, 20.09.2021
https://doi.org/10.54005/geneltip.996549

Öz

Objective: Autism spectrum disorder (ASD) is an important neurodevelopmental disorder, that manifests itself in the decline of the social interaction and communication, learning, and language skills in early childhood. The aim of this study was to measure the general knowledge of the parents have children diagnosed with ASD , to determine their attitudes towards vaccination, to determinate the rate and reason of anti- vaccination.

Material and Methods: The study was carried out by conducting a survey, by means of talking face to face one of ASD diganosed children’s parents.

Results: According to the data obtained, when compared to the control group’s and ASD parents; have higher level of knowledege about vaccines, and preference of vaccination refusal, have higher rate of doubt related with Ingredients of vaccines, and believe that; there was a temporarly connection between onset of autism, and especially live viral vaccines.

Conlcusion: Thoughts, worries, and drawbaks of the families should be evaluated during the routine control of cihildren dignosed as ASD, by child and adolescent psychatrists.

Kaynakça

  • American Psychiatry Association. Diagnostic and Statistical Manual of Mental disorders-DSM-5, 2013, Washington, USA.
  • Prevalence of Autism Spectrum Disorder Among Children Aged 8 Years Autism and Developmental Disabilities Monitoring Network, 11 Sites, United States. 2016 https://www.cdc.gov/mmwr/volumes/69/ss/ss6904a1.htm?scid=ss6904a1w
  • Chaste  P, Roeder K , Devlin B. The Yin and Yang of Autism Genetics: How Rare De Novo and Common Variations Affect Liability. Annu Rev Genomics Hum Genet, 2017;18:167-87.
  • Colvert E, Tick B, McEwen F et al. Heritability of Autism Spectrum Disorder in a UK Population-Based Twin Sample. JAMA Psychiatry; 2015;72(5):415-23.
  • M Lampi K, Hinkka-Yli-Salomäki S, Lehti V, et al. Parental Age and Risk of Autism Spectrum Disorders in a Finnish National Birth Cohort. J Autism Dev Disord, 2013;43(11):2526-35.
  • V Ratajczak H. Theoretical Aspects of Autism: Causes A Reviev. J Immunotoxicol; 2011;8(1):68-79.
  • O’Connell KS, McGregor NW, Lochner C, Emsley R, Warnich L. The Genetic Architecture of Schizophrenia, Bipolar Disorder, Obsessive-Compulsive Disorder and Autism Spectrum Disorder. Mol Cell Neurosci; 2018;88:300-7.
  • Keller R, Basta R, Salerno L, Elia M. Autism, Epilepsy, and Synaptopathies: A Not Rare Association. Neurol Sci; 2017;38(8):1353-61.
  • Geier DA, Geier MR. An Assessment of the Impact of Thimerosal on Childhood Neurodevelopmental Disorder. Pediatr Rehabil, 2003;6(2):97-102.
  • Geier DA, Geier MR. Neurodevelopmental Disorders Following Thimerosal-Containing Childhood Immunizations: A Follow-Up Analysis. Int J Toxicol 2004;23(6):369-76.
  • Hviid A, Vinsløv Hansen J , Frisch M, Melbye M. Measles, Mumps, Rubella Vaccination and Autism: A Nationwide Cohort Study. Ann Intern Med; 2019;170(8):513-20.
  • World Health Organization, MMR and Autism. https://www.who.int/vaccine_safety/committee/topics/mmr/Dec_2002/en/
  • Özdemir İN. Ebeveynlerin Çocukluk Çağı Aşılarına Karşı Bilgi Tutum ve Davranışları, Marmara Üniversitesi Sağlık Bilimleri Enstitüsü, Yüksek Lisans Tezi, 2017, İstanbul. (Danışman: Doç. Dr. Hasibe Kadıoğlu)
  • Çalıklar, Ö, Kadıoğlu H. Validity and reliability of the Turkish Version of the Healthy Family Parenting Inventory. J Psychiatric Nurs, 2020;11(1): 49-56.
  • Price CS, Thompson WW, Goodson B, et al. Prenatal and infant exposure to thimerosal from vaccines and immunoglobulins and risk of autism. Pediatrics 2010;126(4):656-64.
  • Farrington CP, Milner E, Taylor B. MMR and autism: further evidence agaist a casual association. Vaccine 2001;19:3632-5.
  • Zerbo O, Modaressi S, Goddard K, et al. Vaccination patterns in children after autism spectrum disorder diagnosis and in their younger siblings; JAMA Pediatr. 2018;172(5):469-75.
  • Çıkar S, Güner PD. Annelerin Çocukluk Çağı Aşıları Hakkındaki Bilgi, Davranış ve Tutumları ve Aşı Reddi Nedenleri: Nitel ve Nicel Bir Araştırma. Ankara Med J, 2020;(1):180-95.
  • Benin AL, Wisler-Scher DJ, Colson E, Shapiro ED, Holmboe ES. Qualitative analysis of mothers’ decision-making about vaccines for infants: the importance of trust. Pediatrics 2006;117(5):1532-41.
  • Wakefield AJ, Murch SH, Anthony A, et al. Ileal-lymphoid-nodular hyperplasia, nonspecific colitis, and pervasive developmental disorder in children. Lancet 1998;351:637-41.
  • DeStefano F, Price CS, Weintraub ES. Increasing exposure to antibody-stimulating proteins and polysaccharides in Vaccines Is not associated with risk of autism. J Pediatr 2013;163:561-7.
  • Madsen KM, Lauritsen MB, Pedersen CB, et al. Thimerosal and the occurence of autism: negatif ecological evidence from Danish population-based data. Pediatrics. 2003 12(3):604-6.
  • Hornig M, Briese T, Buie T, et al. Lack of association between measles virus vaccine and autism with enteropathy: A case-control study. PLoS One. 2008; 3(9): e3140. doi: 0.1371/journal.pone.0003140.
  • Taylor B, Miller E, Farrington CP, et al. Autism and measles, mumps, and rubella vaccine: no epidemiological evidence for a causal association. Lancet 1999;353:2026-29.
  • Madsen KM, Hviid A, Vestergaard M, et al. A population-based study of measles, mumps, and rubella vaccination and autism. N Engl J Med 2002;347(19):1477-82.

Türkiye’nin farklı bölgelerinde otizmli çocuğu olan ailelerin aşılar hakkındaki bilgi düzeylerinin, aşı reddinin sıklığının, ve nedenlerinin araştırılması.

Yıl 2021, Cilt: 31 Sayı: 3, 225 - 231, 20.09.2021
https://doi.org/10.54005/geneltip.996549

Öz

Amaç: Otizm spektrum bozukluğu (OSB), erken çocukluk dönemlerinde sosyal etkileşim ve iletişim becerilerinde yetersizlik, kısıtlı ilgi alanı ve stereotipik davranış örüntüleri ile karakterize nörogelişimsel önemli bir bozukluktur. Bu çalışmanın amacı OSB tanısı almış çocuğu olan ebeveynlerin aşılar hakkında genel bilgilerini ölçme, aşıya karşı tutumlarını belirleme, aşı karşıtlığının oranı ve nedenlerini saptamaktır.

Gereç ve Yöntem: Çalışma, OSB tanılı çocukları olan ebeveynlerden birisi ile, yüz yüze görüşmek sureti ile, anket yaparak gerçekleştirilmiştir.

Bulgular: Elde edilen verilere göre; kontrol grubu ile karşılaştırıldığında, otizmli çocukları olan ebeveynlerin; aşılar hakkındaki bilgi düzeylerinin, ve aşı reddi tercihlerinin daha yüksek olduğu, aşıların içeriklerinden daha çok şüphe duydukları, özellikle canlı virus aşılaması ile otizmin başlaması arasında, zamansal ilişki olduğuna inandıkları belirlenmiştir.

Sonuç: OSB tanılı çocukların rutin çocuk-ergen psikiyatristleri tarafından, rutin kontrollerinde; ailelerin aşılar hakkındaki düşünceleri, kaygıları ve kaçınmaları değerlendirilmelidir.

Kaynakça

  • American Psychiatry Association. Diagnostic and Statistical Manual of Mental disorders-DSM-5, 2013, Washington, USA.
  • Prevalence of Autism Spectrum Disorder Among Children Aged 8 Years Autism and Developmental Disabilities Monitoring Network, 11 Sites, United States. 2016 https://www.cdc.gov/mmwr/volumes/69/ss/ss6904a1.htm?scid=ss6904a1w
  • Chaste  P, Roeder K , Devlin B. The Yin and Yang of Autism Genetics: How Rare De Novo and Common Variations Affect Liability. Annu Rev Genomics Hum Genet, 2017;18:167-87.
  • Colvert E, Tick B, McEwen F et al. Heritability of Autism Spectrum Disorder in a UK Population-Based Twin Sample. JAMA Psychiatry; 2015;72(5):415-23.
  • M Lampi K, Hinkka-Yli-Salomäki S, Lehti V, et al. Parental Age and Risk of Autism Spectrum Disorders in a Finnish National Birth Cohort. J Autism Dev Disord, 2013;43(11):2526-35.
  • V Ratajczak H. Theoretical Aspects of Autism: Causes A Reviev. J Immunotoxicol; 2011;8(1):68-79.
  • O’Connell KS, McGregor NW, Lochner C, Emsley R, Warnich L. The Genetic Architecture of Schizophrenia, Bipolar Disorder, Obsessive-Compulsive Disorder and Autism Spectrum Disorder. Mol Cell Neurosci; 2018;88:300-7.
  • Keller R, Basta R, Salerno L, Elia M. Autism, Epilepsy, and Synaptopathies: A Not Rare Association. Neurol Sci; 2017;38(8):1353-61.
  • Geier DA, Geier MR. An Assessment of the Impact of Thimerosal on Childhood Neurodevelopmental Disorder. Pediatr Rehabil, 2003;6(2):97-102.
  • Geier DA, Geier MR. Neurodevelopmental Disorders Following Thimerosal-Containing Childhood Immunizations: A Follow-Up Analysis. Int J Toxicol 2004;23(6):369-76.
  • Hviid A, Vinsløv Hansen J , Frisch M, Melbye M. Measles, Mumps, Rubella Vaccination and Autism: A Nationwide Cohort Study. Ann Intern Med; 2019;170(8):513-20.
  • World Health Organization, MMR and Autism. https://www.who.int/vaccine_safety/committee/topics/mmr/Dec_2002/en/
  • Özdemir İN. Ebeveynlerin Çocukluk Çağı Aşılarına Karşı Bilgi Tutum ve Davranışları, Marmara Üniversitesi Sağlık Bilimleri Enstitüsü, Yüksek Lisans Tezi, 2017, İstanbul. (Danışman: Doç. Dr. Hasibe Kadıoğlu)
  • Çalıklar, Ö, Kadıoğlu H. Validity and reliability of the Turkish Version of the Healthy Family Parenting Inventory. J Psychiatric Nurs, 2020;11(1): 49-56.
  • Price CS, Thompson WW, Goodson B, et al. Prenatal and infant exposure to thimerosal from vaccines and immunoglobulins and risk of autism. Pediatrics 2010;126(4):656-64.
  • Farrington CP, Milner E, Taylor B. MMR and autism: further evidence agaist a casual association. Vaccine 2001;19:3632-5.
  • Zerbo O, Modaressi S, Goddard K, et al. Vaccination patterns in children after autism spectrum disorder diagnosis and in their younger siblings; JAMA Pediatr. 2018;172(5):469-75.
  • Çıkar S, Güner PD. Annelerin Çocukluk Çağı Aşıları Hakkındaki Bilgi, Davranış ve Tutumları ve Aşı Reddi Nedenleri: Nitel ve Nicel Bir Araştırma. Ankara Med J, 2020;(1):180-95.
  • Benin AL, Wisler-Scher DJ, Colson E, Shapiro ED, Holmboe ES. Qualitative analysis of mothers’ decision-making about vaccines for infants: the importance of trust. Pediatrics 2006;117(5):1532-41.
  • Wakefield AJ, Murch SH, Anthony A, et al. Ileal-lymphoid-nodular hyperplasia, nonspecific colitis, and pervasive developmental disorder in children. Lancet 1998;351:637-41.
  • DeStefano F, Price CS, Weintraub ES. Increasing exposure to antibody-stimulating proteins and polysaccharides in Vaccines Is not associated with risk of autism. J Pediatr 2013;163:561-7.
  • Madsen KM, Lauritsen MB, Pedersen CB, et al. Thimerosal and the occurence of autism: negatif ecological evidence from Danish population-based data. Pediatrics. 2003 12(3):604-6.
  • Hornig M, Briese T, Buie T, et al. Lack of association between measles virus vaccine and autism with enteropathy: A case-control study. PLoS One. 2008; 3(9): e3140. doi: 0.1371/journal.pone.0003140.
  • Taylor B, Miller E, Farrington CP, et al. Autism and measles, mumps, and rubella vaccine: no epidemiological evidence for a causal association. Lancet 1999;353:2026-29.
  • Madsen KM, Hviid A, Vestergaard M, et al. A population-based study of measles, mumps, and rubella vaccination and autism. N Engl J Med 2002;347(19):1477-82.
Toplam 25 adet kaynakça vardır.

Ayrıntılar

Birincil Dil Türkçe
Konular Klinik Tıp Bilimleri
Bölüm Original Article
Yazarlar

Recep Keşli Bu kişi benim

Yasin Dünya Bu kişi benim

Aldulmanoor Zaheer Bu kişi benim

Danyal Rezazadeh Roudkoli Bu kişi benim

Rukiye Gün Bu kişi benim

Mehmet Bardak Bu kişi benim

Esra Zeynep Yücesan Bu kişi benim

Muhammed Rasim Demirayak Bu kişi benim

Fadime Özge Dilcioğlu Bu kişi benim

Fatma Beyza Öztürk Bu kişi benim

Bayram Şener Bu kişi benim

Mesut Turhan Bu kişi benim

Emek Can Özkan Bu kişi benim

Fatih Hilmi Çetin

Yüksel Terzi

Yayımlanma Tarihi 20 Eylül 2021
Gönderilme Tarihi 28 Aralık 2020
Yayımlandığı Sayı Yıl 2021 Cilt: 31 Sayı: 3

Kaynak Göster

Vancouver Keşli R, Dünya Y, Zaheer A, Roudkoli DR, Gün R, Bardak M, Yücesan EZ, Demirayak MR, Dilcioğlu FÖ, Öztürk FB, Şener B, Turhan M, Özkan EC, Çetin FH, Terzi Y. Türkiye’nin farklı bölgelerinde otizmli çocuğu olan ailelerin aşılar hakkındaki bilgi düzeylerinin, aşı reddinin sıklığının, ve nedenlerinin araştırılması. Genel Tıp Derg. 2021;31(3):225-31.