BibTex RIS Kaynak Göster

KEÇİBOYNUZU EKSTRAKTINDA BULUNAN D-PİNİTOLÜN ÇOK AŞAMALI ZENGİNLEŞTİRME PROSESİ İLE KONSANTRASYONU

Yıl 2015, Cilt: 40 Sayı: 3, 125 - 132, 01.06.2015

Öz

-

Kaynakça

  • Batlle, I, Tous, J. 1997. Promoting the conservation and use of underutilized and neglected crops. 17. Carob tree: Ceratonia siliqua L. 17. Institute of Plant Genetics and Crop Plant Research, Gatersleben/International Plant Genetic Resources Institute, Rome, Italy.
  • Bravo, L, Saura-Calixto, F. 1994. Composition and potential uses of mesquite pods (Prosopis pallida L): comparison with carob pods (Ceratonia siliqua L). J. Sci. Food Agric., 65, 303-306.
  • Avallone, R, Plessi, M, Baraldi, M, Monzani, A. 1997. Determination of chemical composition of carob (Ceratonia siliqua): Protein, fat, carbohydrates, and tannins. J. Food Compos. Anal., 10, 166-172.
  • Biner, B, Gubbuk, H, Karhan, M, Aksu, M, Pekmezci, M. 2007. Sugar profiles of the pods of cultivated and wild types of carob bean (Ceratonia siliqua L.) in Turkey. Food Chem., 100, 1453-1455. 5. Petit, MD, Pinilla, JM. 1995. Production and purification of a sugar syrup from carob pods. LWT - Food Science and Technology, 28, 145-152.
  • Baumgartner, S, Genner-Ritzmann, R, Haas, J, Amado, R, Neukom, H. 1986. Isolation and identification of cyclitols in carob pods (Ceratonia siliqua L.). J. Agric. Food. Chem., 34, 827-829.
  • Tetik, N, Turhan, I, Oziyci, HR, Karhan, M. 2011. Determination of D-pinitol in carob syrup. Int. J. Food Sci. Nutr., 62, 572-576.
  • Poongothai, G, Sripathi, SK. 2013. A review on insulinomimetric pinitol from plants. International Journal of Pharma and Bio Sciences, 4, 992-1009. 9. Ostlund, RE, Sherman, WR. October 1998. Pinitol and derivatives thereof for the treatment of metabolic disorders, US Patent US5827896 A.
  • Kim, JI, Kim, J, Kang, MJ, Lee, MS, Kim, JJ, Cha, IJ. 2004. Effects of pinitol isolated from soybeans on glycaemic control and cardiovascular risk factors in Korean patients with type II diabetes mellitus: a randomized controlled study. Eur. J. Clin. Nutr., 59, 456-458.
  • Geethan, P, Prince, P. 2008. Antihyperlipidemic effect of D-pinitol on streptozotocin-induced diabetic wistar rats. J. Biochem. Mol. Toxicol., 22, 220-224.
  • Lin, TH, Tan, TW, Tsai, TH, Chen, CC, Hsieh, TF, Lee, SS, Liu, HH, Chen, WC, Tang, CH. 2013. D-pinitol inhibits prostate cancer metastasis through inhibition of αVβ3 integrin by modulating FAK, c-Src and NF-κB pathways. Int. J. of Mol. Sci., 14, 9790-9802.
  • Nestler, JE, Jakubowicz, DJ, Reamer, P, Gunn, RD, Allan, G. 1999. Ovulatory and metabolic effects of D-chiro-inositol in the polycystic ovary syndrome. N. Engl. J. Med., 340, 1314-1320.
  • Lin, X, Ma, L, Gopalan, C, Ostlund, RE. 2009. D-chiro-Inositol is absorbed but not synthesised in rodents. Br. J. Nutr., 102, 1426-1434.
  • Streeter, JG. 2001. Simple partial purification of D-pinitol from soybean leaves. Crop Sci., 41, 1985-1987.
  • Shin, YC, Jeon, YJ, Kim, JJ, Choi, CM. October 2003. Method of recovering pinitol or chiro-inositol in high yield from soy fractions, US Patent US20030186401 A1.
  • Camero, BM, Merino, CS. March 2004. Method of obtaining pinitol from carob extracts. US Patent US6699511 B2.
  • Rabinowitz, I. March 1992. Chromatographic method of purifying cyclitols, US Patent US5096594 A.
  • Turhan, I, Bialka, KL, Demirci, A, Karhan, M. 2010. Ethanol production from carob extract by using Saccharomyces cerevisiae. Bioresour. Technol., 101, 5290-5296.
  • Wisselink, HW, Toirkens, MJ, Wu, Q, Pronk, JT, Van Maris, AJ. 2009. Novel evolutionary engineering approach for accelerated utilization of glucose, xylose, and arabinose mixtures by engineered Saccharomyces cerevisiae strains. Appl. Environ. Microbiol., 75, 907-914.
  • Hahn-Hägerdal, B, Karhumaa, K, Jeppsson, M, Gorwa-Grauslund, MF. 2007. Metabolic engineering for pentose utilization in Saccharomyces cerevisiae, Advances in Biochemical Engineering/Biotechnology: Biofuels, 108, 147-177.
  • Cemeroğlu, B. 2007. Gıda Analizlerinde Genel Yöntemler, Gıda Analizleri, Gıda Teknolojisi Derneği Yayınları No:34, Ankara, 535 p.
  • Yoon, SH, Mukerjea, R, Robyt, JF. 2003. Specificity of yeast (Saccharomyces cerevisiae) in removing carbohydrates by fermentation. Carbohydr. Res., 338, 1127-1132.
  • Agrawal, P, Rabinowitz, I. May 1997. Method of purifying cyclitols, US Patent US5626847 A.
  • Roukas, T. 1993. Ethanol production from carob pods by Saccharomyces cerevisiae. Food Biotechnol., 7 (1993) 159-176.

CONCENTRATION OF D-PINITOL in CAROB EXTRACT by USING MULTI-STAGE ENRICHMENT PROCESSES

Yıl 2015, Cilt: 40 Sayı: 3, 125 - 132, 01.06.2015

Öz

D-pinitol, a cyclic sugar alcohol, is claimed to be a potential therapeutic compound related to theillnesses arising from insulin mechanism. Carob is a rich source of this compound and has recentlybegun to be used in different separation and purification studies for obtaining D-pinitol. In this study,different enrichment processes were applied to concentrate the D-pinitol content of the carob extract.To determine the effectiveness of the processes applied for concentration of the target compound incarob extract, removal of other impurities (mainly sugars) was used as an important indicator. Accordingto the results; the highest increase in D-pinitol concentration was observed in the enrichment processcombining the techniques such as ethanol fermentation, membrane filtration and solvent extraction. Atthe end of this multi-stage process, D-pinitol concentration increased approximately four-fold (37.53g/100 mL dry weight) when compared to its initial level (9.38 g/100 mL dry weight) in carob extract

Kaynakça

  • Batlle, I, Tous, J. 1997. Promoting the conservation and use of underutilized and neglected crops. 17. Carob tree: Ceratonia siliqua L. 17. Institute of Plant Genetics and Crop Plant Research, Gatersleben/International Plant Genetic Resources Institute, Rome, Italy.
  • Bravo, L, Saura-Calixto, F. 1994. Composition and potential uses of mesquite pods (Prosopis pallida L): comparison with carob pods (Ceratonia siliqua L). J. Sci. Food Agric., 65, 303-306.
  • Avallone, R, Plessi, M, Baraldi, M, Monzani, A. 1997. Determination of chemical composition of carob (Ceratonia siliqua): Protein, fat, carbohydrates, and tannins. J. Food Compos. Anal., 10, 166-172.
  • Biner, B, Gubbuk, H, Karhan, M, Aksu, M, Pekmezci, M. 2007. Sugar profiles of the pods of cultivated and wild types of carob bean (Ceratonia siliqua L.) in Turkey. Food Chem., 100, 1453-1455. 5. Petit, MD, Pinilla, JM. 1995. Production and purification of a sugar syrup from carob pods. LWT - Food Science and Technology, 28, 145-152.
  • Baumgartner, S, Genner-Ritzmann, R, Haas, J, Amado, R, Neukom, H. 1986. Isolation and identification of cyclitols in carob pods (Ceratonia siliqua L.). J. Agric. Food. Chem., 34, 827-829.
  • Tetik, N, Turhan, I, Oziyci, HR, Karhan, M. 2011. Determination of D-pinitol in carob syrup. Int. J. Food Sci. Nutr., 62, 572-576.
  • Poongothai, G, Sripathi, SK. 2013. A review on insulinomimetric pinitol from plants. International Journal of Pharma and Bio Sciences, 4, 992-1009. 9. Ostlund, RE, Sherman, WR. October 1998. Pinitol and derivatives thereof for the treatment of metabolic disorders, US Patent US5827896 A.
  • Kim, JI, Kim, J, Kang, MJ, Lee, MS, Kim, JJ, Cha, IJ. 2004. Effects of pinitol isolated from soybeans on glycaemic control and cardiovascular risk factors in Korean patients with type II diabetes mellitus: a randomized controlled study. Eur. J. Clin. Nutr., 59, 456-458.
  • Geethan, P, Prince, P. 2008. Antihyperlipidemic effect of D-pinitol on streptozotocin-induced diabetic wistar rats. J. Biochem. Mol. Toxicol., 22, 220-224.
  • Lin, TH, Tan, TW, Tsai, TH, Chen, CC, Hsieh, TF, Lee, SS, Liu, HH, Chen, WC, Tang, CH. 2013. D-pinitol inhibits prostate cancer metastasis through inhibition of αVβ3 integrin by modulating FAK, c-Src and NF-κB pathways. Int. J. of Mol. Sci., 14, 9790-9802.
  • Nestler, JE, Jakubowicz, DJ, Reamer, P, Gunn, RD, Allan, G. 1999. Ovulatory and metabolic effects of D-chiro-inositol in the polycystic ovary syndrome. N. Engl. J. Med., 340, 1314-1320.
  • Lin, X, Ma, L, Gopalan, C, Ostlund, RE. 2009. D-chiro-Inositol is absorbed but not synthesised in rodents. Br. J. Nutr., 102, 1426-1434.
  • Streeter, JG. 2001. Simple partial purification of D-pinitol from soybean leaves. Crop Sci., 41, 1985-1987.
  • Shin, YC, Jeon, YJ, Kim, JJ, Choi, CM. October 2003. Method of recovering pinitol or chiro-inositol in high yield from soy fractions, US Patent US20030186401 A1.
  • Camero, BM, Merino, CS. March 2004. Method of obtaining pinitol from carob extracts. US Patent US6699511 B2.
  • Rabinowitz, I. March 1992. Chromatographic method of purifying cyclitols, US Patent US5096594 A.
  • Turhan, I, Bialka, KL, Demirci, A, Karhan, M. 2010. Ethanol production from carob extract by using Saccharomyces cerevisiae. Bioresour. Technol., 101, 5290-5296.
  • Wisselink, HW, Toirkens, MJ, Wu, Q, Pronk, JT, Van Maris, AJ. 2009. Novel evolutionary engineering approach for accelerated utilization of glucose, xylose, and arabinose mixtures by engineered Saccharomyces cerevisiae strains. Appl. Environ. Microbiol., 75, 907-914.
  • Hahn-Hägerdal, B, Karhumaa, K, Jeppsson, M, Gorwa-Grauslund, MF. 2007. Metabolic engineering for pentose utilization in Saccharomyces cerevisiae, Advances in Biochemical Engineering/Biotechnology: Biofuels, 108, 147-177.
  • Cemeroğlu, B. 2007. Gıda Analizlerinde Genel Yöntemler, Gıda Analizleri, Gıda Teknolojisi Derneği Yayınları No:34, Ankara, 535 p.
  • Yoon, SH, Mukerjea, R, Robyt, JF. 2003. Specificity of yeast (Saccharomyces cerevisiae) in removing carbohydrates by fermentation. Carbohydr. Res., 338, 1127-1132.
  • Agrawal, P, Rabinowitz, I. May 1997. Method of purifying cyclitols, US Patent US5626847 A.
  • Roukas, T. 1993. Ethanol production from carob pods by Saccharomyces cerevisiae. Food Biotechnol., 7 (1993) 159-176.
Toplam 23 adet kaynakça vardır.

Ayrıntılar

Diğer ID JA97FD77ZD
Bölüm Araştırma Makalesi
Yazarlar

Hatice Reyhan Oziyci Bu kişi benim

İrfan Turhan Bu kişi benim

Nedim Tetik Bu kişi benim

Asli Arslan Kulcan Bu kişi benim

Tugba Akkoyun Bu kişi benim

Ercan Yatmaz Bu kişi benim

Mustafa Germec Bu kişi benim

Mustafa Karhan Bu kişi benim

Yayımlanma Tarihi 1 Haziran 2015
Yayımlandığı Sayı Yıl 2015 Cilt: 40 Sayı: 3

Kaynak Göster

APA Oziyci, H. R., Turhan, İ., Tetik, N., Kulcan, A. A., vd. (2015). KEÇİBOYNUZU EKSTRAKTINDA BULUNAN D-PİNİTOLÜN ÇOK AŞAMALI ZENGİNLEŞTİRME PROSESİ İLE KONSANTRASYONU. Gıda, 40(3), 125-132.
AMA Oziyci HR, Turhan İ, Tetik N, Kulcan AA, Akkoyun T, Yatmaz E, Germec M, Karhan M. KEÇİBOYNUZU EKSTRAKTINDA BULUNAN D-PİNİTOLÜN ÇOK AŞAMALI ZENGİNLEŞTİRME PROSESİ İLE KONSANTRASYONU. GIDA. Haziran 2015;40(3):125-132.
Chicago Oziyci, Hatice Reyhan, İrfan Turhan, Nedim Tetik, Asli Arslan Kulcan, Tugba Akkoyun, Ercan Yatmaz, Mustafa Germec, ve Mustafa Karhan. “KEÇİBOYNUZU EKSTRAKTINDA BULUNAN D-PİNİTOLÜN ÇOK AŞAMALI ZENGİNLEŞTİRME PROSESİ İLE KONSANTRASYONU”. Gıda 40, sy. 3 (Haziran 2015): 125-32.
EndNote Oziyci HR, Turhan İ, Tetik N, Kulcan AA, Akkoyun T, Yatmaz E, Germec M, Karhan M (01 Haziran 2015) KEÇİBOYNUZU EKSTRAKTINDA BULUNAN D-PİNİTOLÜN ÇOK AŞAMALI ZENGİNLEŞTİRME PROSESİ İLE KONSANTRASYONU. Gıda 40 3 125–132.
IEEE H. R. Oziyci, “KEÇİBOYNUZU EKSTRAKTINDA BULUNAN D-PİNİTOLÜN ÇOK AŞAMALI ZENGİNLEŞTİRME PROSESİ İLE KONSANTRASYONU”, GIDA, c. 40, sy. 3, ss. 125–132, 2015.
ISNAD Oziyci, Hatice Reyhan vd. “KEÇİBOYNUZU EKSTRAKTINDA BULUNAN D-PİNİTOLÜN ÇOK AŞAMALI ZENGİNLEŞTİRME PROSESİ İLE KONSANTRASYONU”. Gıda 40/3 (Haziran 2015), 125-132.
JAMA Oziyci HR, Turhan İ, Tetik N, Kulcan AA, Akkoyun T, Yatmaz E, Germec M, Karhan M. KEÇİBOYNUZU EKSTRAKTINDA BULUNAN D-PİNİTOLÜN ÇOK AŞAMALI ZENGİNLEŞTİRME PROSESİ İLE KONSANTRASYONU. GIDA. 2015;40:125–132.
MLA Oziyci, Hatice Reyhan vd. “KEÇİBOYNUZU EKSTRAKTINDA BULUNAN D-PİNİTOLÜN ÇOK AŞAMALI ZENGİNLEŞTİRME PROSESİ İLE KONSANTRASYONU”. Gıda, c. 40, sy. 3, 2015, ss. 125-32.
Vancouver Oziyci HR, Turhan İ, Tetik N, Kulcan AA, Akkoyun T, Yatmaz E, Germec M, Karhan M. KEÇİBOYNUZU EKSTRAKTINDA BULUNAN D-PİNİTOLÜN ÇOK AŞAMALI ZENGİNLEŞTİRME PROSESİ İLE KONSANTRASYONU. GIDA. 2015;40(3):125-32.

by-nc.png

GIDA Dergisi Creative Commons Atıf-Gayri Ticari 4.0 (CC BY-NC 4.0) Uluslararası Lisansı ile lisanslanmıştır. 

GIDA / The Journal of FOOD is licensed under a Creative Commons Attribution-Non Commercial 4.0 International (CC BY-NC 4.0).

https://creativecommons.org/licenses/by-nc/4.0/