Yıl 2019, Cilt 44 , Sayı 5, Sayfalar 810 - 818 2019-08-17

CHARACTERIZATION OF RESVERATROL LOADED CELLULOSE ACETATE FIBERS
RESVERATROL YÜKLÜ SELÜLOZ ASETAT LİFLERİNİN KARAKTERİZASYONU

Fahriye Ceyda Dudak Şeker [1]


In this work, encapsulation matrices were fabricated by electrospinning of cellulose acetate solution and their performance for the encapsulation of resveratrol was evaluated. Scanning electron microscopy (SEM) results showed that cellulose acetate fibers were bead-free and smooth. The mean diameters of resveratrol loaded and unloaded fibers were found to be 493 nm and 478 nm, respectively. Encapsulation efficiency of resveratrol was 95%. Antioxidant activity assay confirmed that the encapsulation via electrospun fibers reduced the degradation of bioactive compounds during storage. In-vitro release study showed that 11% of the resveratrol in cellulose acetate fibers was released into buffer medium within 20 h and after that, the release reached plateau. Therefore, electrospun cellulose acetate fibers are promising to be used as an efficient encapsulating matrices for resveratrol.

Bu çalışmada, selüloz asetat çözeltisinden elektroeğirme prosesi ile enkapsülasyon matrisleri üretilmiş ve bu matrislerin resveratrolün enkapsülasyonundaki performansları incelenmiştir. Taramalı elektron mikroskobu (SEM) ile incelendiğinde, selüloz asetat liflerinin düzgün yüzeyli olduğu ve damlacık içermediği görülmüştür. Resveratrol yüklü liflerin ve yüksüz liflerin ortalama çapları sırasıyla 493 nm ve 478 nm olarak belirlenmiştir. Resveratrolün enkapsülasyon etkinliği %94.5 olarak bulunmuştur. Antioksidan aktivite analizi, depolama sırasında elektroeğrilmiş liflere enkapsülasyon ile biyoaktif bileşiğin bozunmasının azaldığını ortaya koymuştur. In vitro salınım çalışması, 20 saat içerisinde başlangıçtaki resveratrolün %11’inin tampon ortamına salındığını ve sonrasında salınımın durduğunu göstermiştir. Sonuç olarak, elektroeğrilmiş selüloz asetat liflerinin resveratrol için etkin enkapsülasyon matrisleri olarak kullanılma potansiyeli olduğu belirlenmiştir.

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Yazar: Fahriye Ceyda Dudak Şeker (Sorumlu Yazar)
Kurum: HACETTEPE ÜNİVERSİTESİ, MÜHENDİSLİK FAKÜLTESİ, GIDA MÜHENDİSLİĞİ BÖLÜMÜ
Ülke: Turkey


Tarihler

Yayımlanma Tarihi : 17 Ağustos 2019

Bibtex @araştırma makalesi { gida585131, journal = {Gıda}, issn = {1300-3070}, eissn = {1309-6273}, address = {}, publisher = {Gıda Teknolojisi Derneği}, year = {2019}, volume = {44}, pages = {810 - 818}, doi = {10.15237/gida.GD19098}, title = {RESVERATROL YÜKLÜ SELÜLOZ ASETAT LİFLERİNİN KARAKTERİZASYONU}, key = {cite}, author = {Dudak Şeker, Fahriye Ceyda} }
APA Dudak Şeker, F . (2019). RESVERATROL YÜKLÜ SELÜLOZ ASETAT LİFLERİNİN KARAKTERİZASYONU. Gıda , 44 (5) , 810-818 . DOI: 10.15237/gida.GD19098
MLA Dudak Şeker, F . "RESVERATROL YÜKLÜ SELÜLOZ ASETAT LİFLERİNİN KARAKTERİZASYONU". Gıda 44 (2019 ): 810-818 <https://dergipark.org.tr/tr/pub/gida/issue/47909/585131>
Chicago Dudak Şeker, F . "RESVERATROL YÜKLÜ SELÜLOZ ASETAT LİFLERİNİN KARAKTERİZASYONU". Gıda 44 (2019 ): 810-818
RIS TY - JOUR T1 - RESVERATROL YÜKLÜ SELÜLOZ ASETAT LİFLERİNİN KARAKTERİZASYONU AU - Fahriye Ceyda Dudak Şeker Y1 - 2019 PY - 2019 N1 - doi: 10.15237/gida.GD19098 DO - 10.15237/gida.GD19098 T2 - Gıda JF - Journal JO - JOR SP - 810 EP - 818 VL - 44 IS - 5 SN - 1300-3070-1309-6273 M3 - doi: 10.15237/gida.GD19098 UR - https://doi.org/10.15237/gida.GD19098 Y2 - 2019 ER -
EndNote %0 Gıda RESVERATROL YÜKLÜ SELÜLOZ ASETAT LİFLERİNİN KARAKTERİZASYONU %A Fahriye Ceyda Dudak Şeker %T RESVERATROL YÜKLÜ SELÜLOZ ASETAT LİFLERİNİN KARAKTERİZASYONU %D 2019 %J Gıda %P 1300-3070-1309-6273 %V 44 %N 5 %R doi: 10.15237/gida.GD19098 %U 10.15237/gida.GD19098
ISNAD Dudak Şeker, Fahriye Ceyda . "RESVERATROL YÜKLÜ SELÜLOZ ASETAT LİFLERİNİN KARAKTERİZASYONU". Gıda 44 / 5 (Ağustos 2019): 810-818 . https://doi.org/10.15237/gida.GD19098
AMA Dudak Şeker F . RESVERATROL YÜKLÜ SELÜLOZ ASETAT LİFLERİNİN KARAKTERİZASYONU. GIDA. 2019; 44(5): 810-818.
Vancouver Dudak Şeker F . RESVERATROL YÜKLÜ SELÜLOZ ASETAT LİFLERİNİN KARAKTERİZASYONU. Gıda. 2019; 44(5): 818-810.