RUMENDE LİPİT METABOLİZMASI
Yıl 2004 ,
Sayı: 6, - , 19.08.2014
Osman Küçük
Haydar Özpınar
Öz
Büyük bir indirgeme (redüsiyon) ortamı olan rumende rasyonla alınan yağlar da indirgenirler. Yağlardaki inirgeme, mikroorganizmaların enzimleri tarafından önce hidroliz sonrada hidrolize sonucu açığa çıkan doymamış serbest yağ asitlerini hidrojenleştirme şeklindedir ki bu son olaya yağların biyohidrogenasyonu adı verilir. Biyohidrojenasyonun gerçekleşmesi için önce yağlar hidrolize olmak zorundadır. Rumende biyohidrojenasyondan sorumlu bakteriler selülolitik özelliktedir ve düşük rumen pH sında aktiviteleri azalmaktadır. Linoleik asidin biyohidrojenasyonundaki ara ürünlerinden konjuge linoleik asidin (CLA) insan sağlığına önemli etkileri mevcuttur.
Kaynakça
BAUMGARD, L.H., E. MATITASHVILI, B. A. CORL, D. A. DWYER, AND D. E. BAUMAN 2002.
trans-10, cis-12 Conjugated Linoleic Acid Decreases Lipogenic Rates and Expression of
Genes Involved in Milk Lipid Synthesis in Dairy Cows. J. Dairy Sci. 85:2155-2163.
CZERKAVVSKI. J. W. AND JJ. L. CLAPPERTON 1984. Fats as energy-yielding compounds in the
ruminant diet. İn: J. VViseman (Ed.). pp. 249-263. Fats in Animal Nutrition. Buttervvorts, Boston.
(2004) GIDA ve YEM 3İLİMİ-TEKN0L0JİSİ Sayı: 6
DEVERY R., MİLLER A., AND STANTON C 2001. Conjugated linoleic acid and oxidative behavioul
in cancer celis. Biochem Soc Trans. 29:341-344.
DHIMAN, T. R., L. D. SATTER, M. W. PARIZA, M. P. GALLI, AND K. ALBRIGHT 1997. ConjugateJ
linoleic acid (CLA) content of milk from cows offered diets rich in linoleic and linolenic acidl
J. Dairy Sci. 80:184 (Suppl 1) (Abstr).
DOREAU, M. AND A. FERLAY 1994. Digestion and utilization of fatty acids by ruminnats. Anim. Fe
Sci. Technol. 45:379-396.
DURGAM V. R., FERNANDES G. 1997. The grovvth inhibitory effect of conjugated linoleic acid <
MCF-7 cells is related to estrogen response system. Cancer Lett. 116:121-1301
FERLAY, A., J. CHABROT, Y. ELMEDDAH, AND M. DOREAU 1993. Ruminal lipid balance a f'
intestinal digestion by dairy cows fed calcium salts of rapeseed oil fatty acids or rapese
oil. J. Anim. Sci. 71:2237-2245.
GIESY, J. G„ M. A. MCGUIRE, B. SHAFII, AND T. W. HANSON 2002. Effect of Dose Of Calciuıd
Salts of Conjugated Linoleic Acid (CLA) on Percentage and Fatty Acid Content of Milk Fal
in Midlactation Holstein Cows. J. Dairy Sci. 85:2023-2029.
HA, Y. L., J. STORKSON, AND M. W. PARIZA 1990. Inhibition of benzo- (a)pyrene-induced mousa
forestomach neoplasia by conjugated dienoic derivatives of lineloic acid. Cancer Lett. 50:1097-
-
HARFOOT, C. G., AND G. P. HAZLEVVOOD 1988. Lipid metabolism in the rumen. İN: p. n. Hobson
(Ed.) The Rumen Microbial Ecosystem. pp. 285-322. Elsevier Applied Science, New York.
HAZLEVVOOD, G. P., AND R. M. C. DAVVSON 1975. Isolation and properties of phospholipkj
hydrolysing bacterium from ovine rumen fluid. J. Gen. Microbiol. 89:163-174.1
HECKART, M. L., J. M. EGGERT, A. P. SCHINCKEL, S. E. MILLS, AND S. S. DONKIN 1999. Feedİng
conjugated linoleic acid (CLA) decreases lipogenesis and alters insulin responsiveness in
porcine adipose tis su e explan ts. J. Anim. Sci. 77:119 (Suppl.) (Abstr).
HENDERSON, C. 1971 A study of lipase produced by Anaerovibrio lipolitica, a rumen bacterium.|
J. Gen. Microbiol. 65:81-89.
HUSSEIN, H. S., N. R. MERCHEN, AND G. C. FAHEY, JR. 1996. Effects of chemical treatmentoJ
vvhole canola seed on digestion of long-chain fatty acids by steers fed high or low forage!
diets. J. Dairy Sci. 79:87-97. Jenkins, T. C. 1993. Lipid metabolism in therumen. J. DairJ
Sci. 76:3851-3863.
KELLY, M. L., J. R. BERRY, D. A. DVVYER, D. E. BAUMAN, M. E. VANAMBURGH, AND J. M.
GRIINARI. 1997. Effect of dietary fatty acid sources on conjugated linoleic acid (CLA) levels in milk
from lactating dairy cows. J. Dairy Sci. 80:243 (Suppl 1) (Abstr).
KÜÇÜK, O., B. W. HESS, P. A., LUDDEN, D. C. RULE 2001. Effect of frage: concentrate ratio on
ruminal digestion and duodenal flow of fatty acids in ewes. J. Anim. Sci. 79:2233-2240.
LATHAM, M. J., J. E Storry, and M. E. Sharpe 1972. Effect of low-roughage diets on the microflora
and lipid metabolism in the rumen. Appl. Microbiol. 24:871-877
LEUNG Y.H., LIU R. H. 2000. trans-10, cis-12-conjugated linoleic acid isomer. J Agric Food Chem.
:5469-5475.
LOOR J. J. AND J. H. Herbein 2003. Reduced Fatty Acid Synthesis and Desaturation Due to
Exogenous trans 10, cis 12-CLA in Cows Fed Oleic or Linoleic Oil. J. Dairy Sci. 86:1354-
-
PARİZA, M.W. AND Y. L. HA 1990. Conjugated Linoleic Dienoic Derivatives of Linoliec Acid: Mechanism
of Anticarcinogenic Effect in Mutagens and Carcinogens in the Diet. pp. 217. Wiley-Liss, Inc.
New York.
PERFİELD II. J. W., G. BERNAL-SANTOS, T.R. OVERTON, AND D. E. BAUMAN 2002. effects of
Dietary Supplementation of Rumen-Protected Conjugated Linoleic Acid in Dairy Cows during
(2004) GIDA ve YEM BİLİMİ-TEKNOLOJİSİ 5ayı: 6
Established Lactatin. J. Dairy Sci. 85:2609-2617.
PRİNS, R. A. LANKHORST, P. VAN DER MEER, AND C. J. VAN NEVEL 1975. Some
characteristics of Anaerovibrio lipolitica, a rumen lipolytic organism. Ant. van Leeuvven hoek
J. Microbiol. Serol. 41:1-11
RYDER, J „ D. BAUMAN, C. PORTOCARRERO, X. SONG, M. YU, D. BARBANO, J. ZİERATH,
AND K. HOUSEKNECHT 1999. Anti-carcinogenic effects of dietary conjugated linoleic acid (CLA):
isomer-specific effects on glucose telorance and skeletal musscle glucose transport. J.
Anim Sci. 77:119 (Suppl) (Abtstr).
SİNGH, S., AND J. C. HAVVKE 1979. The in vitro lipolysis and biohyydrogenation of
monogalactosyldiglyceride by whole rumen contents and its fractions. J. Sci. Food Agric.
:603-612.
VAN SOEST, P. J. 1994. Nutritional Ecology of the Ruminant. Cornell Univ. Press. Ithaca,
New York.
WU, Z., O. A. OHAJURUKA, AND D. L. PALMÛUİST 1991. Ruminal synthesis, bioydrogenation,
and digestibility of fatty acids by dairy cows. J. Dairy sCİ. 74:3025-3034.
Yıl 2004 ,
Sayı: 6, - , 19.08.2014
Osman Küçük
Haydar Özpınar
Kaynakça
BAUMGARD, L.H., E. MATITASHVILI, B. A. CORL, D. A. DWYER, AND D. E. BAUMAN 2002.
trans-10, cis-12 Conjugated Linoleic Acid Decreases Lipogenic Rates and Expression of
Genes Involved in Milk Lipid Synthesis in Dairy Cows. J. Dairy Sci. 85:2155-2163.
CZERKAVVSKI. J. W. AND JJ. L. CLAPPERTON 1984. Fats as energy-yielding compounds in the
ruminant diet. İn: J. VViseman (Ed.). pp. 249-263. Fats in Animal Nutrition. Buttervvorts, Boston.
(2004) GIDA ve YEM 3İLİMİ-TEKN0L0JİSİ Sayı: 6
DEVERY R., MİLLER A., AND STANTON C 2001. Conjugated linoleic acid and oxidative behavioul
in cancer celis. Biochem Soc Trans. 29:341-344.
DHIMAN, T. R., L. D. SATTER, M. W. PARIZA, M. P. GALLI, AND K. ALBRIGHT 1997. ConjugateJ
linoleic acid (CLA) content of milk from cows offered diets rich in linoleic and linolenic acidl
J. Dairy Sci. 80:184 (Suppl 1) (Abstr).
DOREAU, M. AND A. FERLAY 1994. Digestion and utilization of fatty acids by ruminnats. Anim. Fe
Sci. Technol. 45:379-396.
DURGAM V. R., FERNANDES G. 1997. The grovvth inhibitory effect of conjugated linoleic acid <
MCF-7 cells is related to estrogen response system. Cancer Lett. 116:121-1301
FERLAY, A., J. CHABROT, Y. ELMEDDAH, AND M. DOREAU 1993. Ruminal lipid balance a f'
intestinal digestion by dairy cows fed calcium salts of rapeseed oil fatty acids or rapese
oil. J. Anim. Sci. 71:2237-2245.
GIESY, J. G„ M. A. MCGUIRE, B. SHAFII, AND T. W. HANSON 2002. Effect of Dose Of Calciuıd
Salts of Conjugated Linoleic Acid (CLA) on Percentage and Fatty Acid Content of Milk Fal
in Midlactation Holstein Cows. J. Dairy Sci. 85:2023-2029.
HA, Y. L., J. STORKSON, AND M. W. PARIZA 1990. Inhibition of benzo- (a)pyrene-induced mousa
forestomach neoplasia by conjugated dienoic derivatives of lineloic acid. Cancer Lett. 50:1097-
-
HARFOOT, C. G., AND G. P. HAZLEVVOOD 1988. Lipid metabolism in the rumen. İN: p. n. Hobson
(Ed.) The Rumen Microbial Ecosystem. pp. 285-322. Elsevier Applied Science, New York.
HAZLEVVOOD, G. P., AND R. M. C. DAVVSON 1975. Isolation and properties of phospholipkj
hydrolysing bacterium from ovine rumen fluid. J. Gen. Microbiol. 89:163-174.1
HECKART, M. L., J. M. EGGERT, A. P. SCHINCKEL, S. E. MILLS, AND S. S. DONKIN 1999. Feedİng
conjugated linoleic acid (CLA) decreases lipogenesis and alters insulin responsiveness in
porcine adipose tis su e explan ts. J. Anim. Sci. 77:119 (Suppl.) (Abstr).
HENDERSON, C. 1971 A study of lipase produced by Anaerovibrio lipolitica, a rumen bacterium.|
J. Gen. Microbiol. 65:81-89.
HUSSEIN, H. S., N. R. MERCHEN, AND G. C. FAHEY, JR. 1996. Effects of chemical treatmentoJ
vvhole canola seed on digestion of long-chain fatty acids by steers fed high or low forage!
diets. J. Dairy Sci. 79:87-97. Jenkins, T. C. 1993. Lipid metabolism in therumen. J. DairJ
Sci. 76:3851-3863.
KELLY, M. L., J. R. BERRY, D. A. DVVYER, D. E. BAUMAN, M. E. VANAMBURGH, AND J. M.
GRIINARI. 1997. Effect of dietary fatty acid sources on conjugated linoleic acid (CLA) levels in milk
from lactating dairy cows. J. Dairy Sci. 80:243 (Suppl 1) (Abstr).
KÜÇÜK, O., B. W. HESS, P. A., LUDDEN, D. C. RULE 2001. Effect of frage: concentrate ratio on
ruminal digestion and duodenal flow of fatty acids in ewes. J. Anim. Sci. 79:2233-2240.
LATHAM, M. J., J. E Storry, and M. E. Sharpe 1972. Effect of low-roughage diets on the microflora
and lipid metabolism in the rumen. Appl. Microbiol. 24:871-877
LEUNG Y.H., LIU R. H. 2000. trans-10, cis-12-conjugated linoleic acid isomer. J Agric Food Chem.
:5469-5475.
LOOR J. J. AND J. H. Herbein 2003. Reduced Fatty Acid Synthesis and Desaturation Due to
Exogenous trans 10, cis 12-CLA in Cows Fed Oleic or Linoleic Oil. J. Dairy Sci. 86:1354-
-
PARİZA, M.W. AND Y. L. HA 1990. Conjugated Linoleic Dienoic Derivatives of Linoliec Acid: Mechanism
of Anticarcinogenic Effect in Mutagens and Carcinogens in the Diet. pp. 217. Wiley-Liss, Inc.
New York.
PERFİELD II. J. W., G. BERNAL-SANTOS, T.R. OVERTON, AND D. E. BAUMAN 2002. effects of
Dietary Supplementation of Rumen-Protected Conjugated Linoleic Acid in Dairy Cows during
(2004) GIDA ve YEM BİLİMİ-TEKNOLOJİSİ 5ayı: 6
Established Lactatin. J. Dairy Sci. 85:2609-2617.
PRİNS, R. A. LANKHORST, P. VAN DER MEER, AND C. J. VAN NEVEL 1975. Some
characteristics of Anaerovibrio lipolitica, a rumen lipolytic organism. Ant. van Leeuvven hoek
J. Microbiol. Serol. 41:1-11
RYDER, J „ D. BAUMAN, C. PORTOCARRERO, X. SONG, M. YU, D. BARBANO, J. ZİERATH,
AND K. HOUSEKNECHT 1999. Anti-carcinogenic effects of dietary conjugated linoleic acid (CLA):
isomer-specific effects on glucose telorance and skeletal musscle glucose transport. J.
Anim Sci. 77:119 (Suppl) (Abtstr).
SİNGH, S., AND J. C. HAVVKE 1979. The in vitro lipolysis and biohyydrogenation of
monogalactosyldiglyceride by whole rumen contents and its fractions. J. Sci. Food Agric.
:603-612.
VAN SOEST, P. J. 1994. Nutritional Ecology of the Ruminant. Cornell Univ. Press. Ithaca,
New York.
WU, Z., O. A. OHAJURUKA, AND D. L. PALMÛUİST 1991. Ruminal synthesis, bioydrogenation,
and digestibility of fatty acids by dairy cows. J. Dairy sCİ. 74:3025-3034.
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