Çocuklarda Mukozit Yönetiminde Kanıt Temelli Uygulamalar

Yıl 2018, Cilt: 7 Sayı: 4, 128 - 133, 28.12.2018

Selda Beşirik , Nejla Canbulat Şahiner

Öz

Çocuklarda Kanıta dayalı uygulamalar, son
bilimsel literatürün sağladığı sonuçlara ulaşarak hemşirelik uygulamalarının
standartlaşmasını sağlar. Çocuklarda Mukozit yönetiminde hemşirelik
uygulamalarında bakımın sonuçlarını iyileştirmek ve kalitesini yükseltmek,  hastanın memnuniyet düzeyini arttırmak ve verilen
hemşirelik bakımını standardize etmek yalnızca kanıta dayalı hemşirelik
uygulamalarıyla mümkündür. Bu derlemede, çocuklarda mukozit yönetiminde kanıt
temelli uygulamalar; sistematik derleme sonuçları, meta-analiz, randomize
kontrollü çalışmalar ve rehberler doğrultusunda ele alındı.  Uygulamalar olarak; Klorheksidin, Benzidamin
Hidroklorid, Sodyum Bikarbonat, Serum Fizyolojik, Kriyoterapi ve Bal başlıklar
altında tartışıldı. Çocuklarda mukozitin önlenmesinde ve tedavisinde
farmakolojik ve nonfarmakolojik uygulamaların kullanıldığı ancak mukozit
yönetiminde standart kabul edilen bir uygulamanın olmadığı görüldü. 

Anahtar Kelimeler

Çocuk, Mukozit, Kemoterapi

Evidence Based Practices in Mucositis Management in Children

Öz

Blood-based
practices in children provide the standardization of nursing practices by
reaching the conclusions of the latest scientific literature. Improving the
quality of care and improving the quality of care in nursing practice in
children under Mukosit administration, increasing the level of patient
satisfaction and standardizing the nursing care provided is only possible with
blood based nursing practices. In this review, evidence-based practices in
mucositis management in children; were handled in the direction of systematic
review results, meta-analysis, randomized controlled trials and guidelines. As
applications; Chlorhexidine, Benzidamine Hydrochloride, Sodium Bicarbonate,
Saline, Cryotherapy and Honey were discussed under the headings. It has been
observed that pharmacological and non-pharmacological applications are used in
the prevention and treatment of mucositis in children, but there is no standard
practice in mucositis management. not be included.

Anahtar Kelimeler

Child, Mucositis, Chemotherapy

Kaynakça

• KAYNAKLAR1. French, P. (2002). What is the evidence on evi-dence-basednursing? An epistemologi-cal concern. Journal of Advanced Nursing; 37(3): 250−257.
• 2. Arslan, S., Şener, D. K., & Küçük, Ö. (2016). Pediatri kliniğinde çalişan hemşirelerin kanita dayali uygulamalara ilişkin görüşleri. Yildirim Beyazit Üniversitesi Hemşirelik E-Dergisi, 3(1).
• 3. Sitzia, J. (2002). Bar. rier store search utilization: the clinical setting and nurses them sel-ves. Intensive and Critical Care Nursing;18, 230–243.
• 4. Mantzoukas, S. (2008).A review of evidence-based practice, nursing research and ref-lection: levelling the hierarchy. Journal of Clinical Nursing; 17, 214-23.
• 5. Bilgin, N. Ç.,& Potur, D. C. (2010). Doğum sonu dönem kanıt temelli yaklaşımlar ve hemşirelik. Maltepe Üniversitesi Hemşirelik Bilim ve Sanatı Dergisi, 3(3), 80-87.
• 6. Çavuşoğlu, H. (2007). Oral mukozit yönetiminde kanıta dayalı hemşirelik. Turkiye Klinikleri Journal of Medical Sciences, 27(3), 398-406.
• 7. Uysal, G., & Sönmez Düzkaya, D. (2013). Çocuk yoğun bakım ünitelerinde kanıta dayalı uygulamalar. Yoğun Bakım Dergisi, 17(1), 29-36.
• 8. Hashemi, A., Bahrololoumi, Z., Khaksar, Y., Saffarzadeh, N., Neamatzade, H., & Foroughi, E. (2015). Mouth-rinses for the prevention of chemotherapy induced oral mucositis in children: a systematic review. Iranian journal of pediatric hematology and oncology, 5(2), 106.
• 9. McGuire, D. B., Fulton, J. S., Park, J., Brown, C. G., Correa, M. E. P., Eilers, J., ... & Lalla, R. V. (2013). Systematic review of basic oral care for the management of oral mucositis in cancer patients. Supportive Care in Cancer, 21(11), 3165-3177.
• 10. Mallick, S., Benson, R., & Rath, G. K. (2016). Radiation induced oral mucositis: a review of current literature on prevention and management. European Archives of Oto-Rhino-Laryngology, 273(9), 2285-2293.
• 11. Papadopoulou, K., Perdikaris, P., Patiraki, E., Giannakopoulou, M., Stamoulara, A., & Matziou, V. (2014). Stomatitis in children with cancer. Nursing Care & Research/Nosileia kai Ereuna, (40).
• 12. Lalla, R. V., Bowen, J., Barasch, A., Elting, L., Epstein, J., Keefe, D. M., ... & Raber‐Durlacher, J. E. (2014). MASCC/ISOO clinical practice guidelines for the management of mucositis secondary to cancer therapy. Cancer, 120(10), 1453-1461.
• 13. Nicolatou-Galitis, O., Sarri, T., Bowen, J., Di Palma, M., Kouloulias, V. E., Niscola, P., ... & Elad, S. (2013). Systematic review of anti-inflammatory agents for the management of oral mucositis in cancer patients. Supportive Care in Cancer, 21(11), 3179-3189.
• 14. Chaveli-López, B., & Bagán-Sebastián, J. V. (2016). Treatment of oral mucositis due to chemotherapy. Journal of clinical and experimental dentistry, 8(2), e201.
• 15. Peterson, D. E., Boers-Doets, C. B., Bensadoun, R. J., & Herrstedt, J. (2015). Management of oral and gastrointestinal mucosal injury: ESMO Clinical Practice Guidelines for diagnosis, treatment, and follow-up. Annals of Oncology, 26(suppl_5), v139-v151.
• 16. Sung, L., Robinson, P., Treister, N., Baggott, T., Gibson, P., Tissing, W., ... & Dupuis, L. L. (2015). Guideline for the prevention of oral and oropharyngeal mucositis in children receiving treatment for cancer or undergoing haematopoietic stem cell transplantation. BMJ supportive & palliative care, bmjspcare-2014.
• 17. Peterson, D. E., Öhrn, K., Bowen, J., Fliedner, M., Lees, J., Loprinzi, C., ... & Lalla, R. V. (2013). Systematic review of oral cryotherapy for management of oral mucositis caused by cancer therapy. Supportive Care in Cancer, 21(1), 327-332.
• 18. Bulut, H. K.,& Tüfekci, F. G. (2016). Honey prevents oral mocositis in children undergoing chemotherapy: A quasi-experimental study with a control group. Complementary therapies in medicine, 29, 132-140.
• 19. Al Jaouni, S. K., Al Muhayawi, M. S., Hussein, A., Elfiki, I., Al-Raddadi, R., Al Muhayawi, S. M., ... & Harakeh, S. (2017). Effects of Honey on Oral Mucositis among Pediatric Cancer Patients Undergoing Chemo/Radiotherapy Treatment at King Abdulaziz University Hospital in Jeddah, Kingdom of Saudi Arabia. Evidence-Based Complementary and Alternative Medicine.
• 20. Friend, A., Rubagumya, F., & Cartledge, P. (2017). Global Health Journal Club: Is Honey Effective as a Treatment for Chemotherapy-induced Mucositis in Paediatric Oncology Patients?. Journal of tropical pediatrics, 64(2), 162-168.
• 21. Babu, K. L. G., Mathew, J., Doddamani, G. M., Narasimhaiah, J. K., & Naik, L. R. K. (2016). Oral health of children with acute lymphoblastic leukemia: A review. Journal of Orofacial Sciences, 8(1), 3.
• 22. Yavuz, B.,& Bal Yılmaz, H. (2015). Investigation of the effects of planned mouth care education on the degree of oral mucositis in pediatric oncology patients. Journal of Pediatric Oncology Nursing, 32(1), 47-56.
• 23. Qutob, A.F., Gue, S., Revesz, T., Logan, R.M., & Keefe, D. (2013). Prevention of oral mucositis in children receiving cancer therapy: A systematic review and evidence-based analysis. Oral Oncology, 49(2):102–07.