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Hemodiyaliz Tedavisi Gören Hastalarda Diyaliz Yeterliliği ile Deneyimledikleri Semptomlar Arasındaki İlişki/ The Relationship Between Dialysis Adequacy and The Symptoms Experienced in Patients Under Hemodialysis Treatment

Yıl 2024, , 43 - 52, 31.05.2024
https://doi.org/10.47565/ndthdt.2024.81

Öz

Amaç: Bu çalışmada, hemodiyaliz tedavisi alan hastaların deneyimledikleri semptomlar ile diyaliz yeterliliği arasındaki ilişkiyi incelemek amaçlandı.
Gereç ve Yöntemler: Bu kesitsel tanımlayıcı türdeki çalışma Nisan 2023-Ocak 2024 tarihleri arasında 109 hemodiyaliz tedavisi alan hasta ile yürütüldü. Veriler ‘Hasta Veri Toplama Formu’ ve ‘Diyaliz Semptom İndeksi’ kullanılarak toplandı. Hastaların diyaliz yeterliliğini değerlendirmek için diyalitik madde klirensi değeri ve üre redüksiyon oranı kullanıldı.
Bulgular: Hastaların yaş ortalaması 62,06±12,75 ve Diyaliz Semptom İndeksi puan ortalaması 22,26±13,58 idi. Hastaların diyalitik madde klirensi ortalaması 1.71±0.34, üre redüksiyon oranı ise %73,49±8,64 idi. Hemodiyaliz hastalarının en sık (%81,7) ve en şiddetli (2,01±1,23) deneyimlediği semptom yorgun hissetme idi. Hemodiyaliz hastalarının Diyaliz Semptom İndeksi puan ortalaması ile hemoglobin düzeyi (r=-0,231; p=0,01), albümin düzeyi (r=-0,223; p=0,02) arasında negatif, fosfor düzeyi arasında ise (r=0,190; p=0,48) pozitif yönlü bir ilişki vardı. Hastaların Diyaliz Semptom İndeksi puan ortalaması ile diyalitik madde klirensi ve ve üre redüksiyon oranı arasında bir ilişki yok idi (p>0,05).
Sonuç: Hemodiyaliz hastalarının deneyimlediği semptomların şiddetti düşük, sıklığı yüksekti. Hastaların en sık ve en şiddetli deneyimlediği semptom yorgun hissetme idi. Hastaların
hemoglobin ve albümin seviyesi düştükçe hastaların deneyimlediği semptomlar arttı. Hastaların deneyimlediği semptom şiddeti ve diyaliz yeterliliği arasında bir ilişki bulunmadı. Hemodiyaliz tedavisi gören hastalarda diyalizin yeterli olmasına rağmen deneyimledikleri semptomların sıklığı yüksek idi. Sağlık profesyonellerinin sistematik olarak hastaların deneyimledikleri semptomları da rutinde değerlendirmeleri önerilmektedir.

Etik Beyan

Bu çalışma için etik komite onayı, Kırklareli Üniversitesi Sağlık Bilimleri Enstitüsü Etik Kurulu'ndan alınmıştır (Tarih 20.03.2023 ve no: PR0456R0). Çalışmaya katılan hastalardan 'bilgilendirilmiş onam’ alındı.

Destekleyen Kurum

Araştırmaya herhangi bir kurum yada kuruluş fon desteğinde bulunmamıştır.

Teşekkür

Çalışmamıza katılarak destek olan tüm hemodiyaliz hastalarına teşekkürlerimizi sunarız.

Kaynakça

  • 1. Süleymanlar G, Utaş C, Arinsoy T, Ateş K, Altun B, Altiparmak MR, ve ark. A population based survey of chronic renal disease in Turkey the CREDIT study. Nephrol Dial Transplant. 2011;26(6):1862-71. https://doi.org/10.1093/ndt/gfq656
  • 2. Varol E, Sivrikaya SK. Kronik böbrek yetmezliğinde yaşam kalitesi ve hemşirelik. DÜ Sağlık Bil Enst Derg [Internet].
  • 2018[cited 2024 Apr 15];8(3):969-76 Available from: https://dergipark.org.tr/tr/download/article-file/504947 3. Abeywickrama HM, Wimalasiri S, Koyama Y, Uchiyama M, Shimizu U, Kakihara N, Chandrajith R, Nanayakkara N. Quality of Life and symptom burden among chronic kidney disease of uncertain etiology (CKDu) patients in Girandurukotte, Sri Lanka. Int. J. Environ. Res. Public Health . 2020;17(11):4041. https://doi.org/10.3390/ijerph17114041
  • 4. Horigan AE, Schneider SM, Docherty S, Barroso J. The experience and self management of fatigue in hemodialysis patients. Nephrol Nurs J [Internet]. 2013[cited 2024 Apr 10];40(2):113-23. Available from: https://www.ncbi.nlm.nih.gov/pmc/ articles/PMC3703392/
  • 5. Şanlıtürk D, Ovayolu N, Kes D. Hemodiyaliz hastalarında sık karşılaşılan problemler ve çözüm önerileri. Nefro Hem Dergi [Internet]. 2013[cited 2024 Apr 10];1(13):17-25. Available from: https://dergipark.org.tr/tr/pub/hemsire/issue/34384/363161
  • 6. Bossola M, Pepe G, Picca A, Calvani R, Marzetti E. Treating symptoms to improve the quality of life in patients on chronic hemodialysis. Int Urol Nephrol. 2019;51(5):885-87. https://doi.org/10.1007/s11255-019-02121-5
  • 7. Horigan AE. Fatigue in hemodialysis patients: A review of current knowledge. J Pain Symptom Manage. 2012;44(5):715-24. https://doi.org/10.1016/j.jpainsymman.2011.10.015
  • 8. Zedelenmez A, Çağlar M. Hemodiyaliz hastalarında yeterli diyaliz en doğru nasıl değerlendirilir? Nefro Hem Dergi [Internet]. 2019[cited 2024 Apr 10];14(2):70-4. Available from: https://dergipark.org.tr/tr/pub/hemsire/issue/45515/497885
  • 9. Evrenkaya TR, Atasoyu M, Ünver S, Gültepe M, Narin Y, Tülbek Y. Hemodiyaliz yeterliliği ile komorbid faktörler arasındaki ilişki. Türk Nefroloji Diyaliz ve Transplantasyon Dergisi [Internet]. 2002[cited 2024 Apr 10];ll(l):44-51. Available from: https://turkjnephrol.org/Content/files/sayilar/385/44-51.pdf
  • 10. Kalender N, Tosun N. Determination of the relationship between adequacy of dialysis and quality of life and selfcare agency. J Clin Nurs. 2014;23(5–6):820–28. https://doi.org/10.1111/jocn.12208 11. Daugirdas JT. Second generation logarithmic estimates of single-pool variable volume Kt/V: An analysis of error. J Am Soc Nephrol. 1993;4(5):1205-13. https://doi.org/10.1681/ASN.V451205
  • 12. Hemodialysis Adequacy 2006 Work Group, Clinical practice guidelines for hemodialysis adequacy, update 2006. Am J Kidney Dis. 2006;48(1):2-90. https://doi.org/10.1053/j.ajkd.2006.03.051.
  • 13. Stolic RV, Trajkovic GZ, Jekic D, Sovtic SR, Jovanovic AN, Stolic DZ, et al. Predictive parameters of survival in hemodialysis patients with restless leg syndrome. Saudi J Kidney Dis Transpl. 2014;25(5):74-80. https://doi.org/10.4103/1319-2442.139869
  • 14. Yapa HE, Purtell L, Chambers S, & Bonner A. The relationship between chronic kidney disease, symptoms and healthrelated quality of life: A systematic review. J Ren Care. 2020;46(2):74-84. https://doi.org/10.1111/jorc.12303
  • 15. Dikmen RD, Aslan H. The effects of the symptoms experienced by patients undergoing hemodialysis treatment on their comfort levels. J Clin Nephrol Ren Care. 2020;6(2):1-9. https://doi.org/10.23937/2572-3286/1510060
  • 16. Ozen N, Cepken T, Sousa CN. Does adequate hemodialysis prevent symptoms?: A national cross-sectional survey. Clin Nurs Res. 2021;30:334–42. https://doi.org/10.1177/1054773820913986
  • 17. Karaaslan T, Pembegul I. Relationship between symptom burden and dialysis adequacy in patients with chronic kidney disease undergoing hemodialysis. North Clin Istanb. 2023;10(4):435-43. https://doi.org/10.14744/nci.2023.01799.
  • 18. Weisbord SD, Fried LF, Arnold RM, Rotondi AJ, Fine MJ, Levenson DJ, et al. Development of a symptom assessment instrument for chronic hemodialysis patients: The dialysis symptom index. J Pain Symptom Manag. 2004;27(3):226-40. https://doi.org/10.1016/j.jpainsymman.2003.07.004
  • 19. Önsöz HB, Usta Yeşilbalkan O. Reliability and validity of the Turkish version of the dialysis symptom index in chronic hemodialysis patients. Turk Neph Dial Transpl. 2013; 22(1):60-7. https://doi.org/10.5262/tndt.2013.1001.08
  • 20. Chaiviboontham S, Phinitkhajorndech N, Tiansaard J. Symptom clusters in patients with end-stage renal disease undergoing hemodialysis. J Nephrol Renovasc Dis. 2020;297-305. https://10.2147/IJNRD.S271619
  • 21. Siriwardana AN, Hoffman AT, Brennan FP, Li K, Brown MA. Impact of renal supportive care on symptom burden in dialysis patients: A prospective observational cohort study. J Pain Symptom Manage. 2020;60(4):725-36. https://doi.org/10.1016/j .jpainsymman.2020.04.030
  • 22. Alkın Demir C, Özer Z. Hemodiyaliz tedavisi alan hastalarda semptom ve konfor ilişkisi. Nefro Hem Dergi. 2022;17(1):10-27. https://doi.org/10.47565/ndthdt.2022.49
  • 23. Akgöz N, Arslan S, Hemodiyaliz tedavisi alan hastalarda yaşanan semptomların incelenmesi. Nefro Hem Dergi [Internet]. 2017 [cited 2024 Apr 10];12(1):20–8. Available from: https://dergipark.org.tr/tr/download/article-file/360008
  • 24. Zamanian H, Kharameh ZT. Translation and psychometric properties of the persian version of the dialysis symptom ındex in hemodialysis patients. Nephro Urol Mon. 2015;7(1):e23152. https://doi.org/10.5812/numonthly.23152
  • 25. Karasneh R, Al-Azzam S, Altawalbeh SM et al. Predictors of symptom burden among hemodialysis patients: A cross-sectional study at 13 hospitals. Int Urol Nephrol. 2020;52(5):959-67. https://doi.org/10.1007/s11255-020-02458-2
  • 26. Özkan İ, Taylan, S. Investigación sobre la relación entre síntomas observados en pacientes en hemodiálisis con la adecuación de diálisis y rasgos de personalidad. Rev Nefrol Dial Traspl [Internet].2020 [cited 2024 Apr 8];40(2):106-18. Available from: https://www.revistarenal.org.ar/index.php/rndt/article/view/520/1014
  • 27. Murtagh FE, Addington-Hall J, Higginson IJ. The prevalence of symptoms in end-stage renal disease: A systematic review, Adv Chronic Kidney Dis. 2007;14(1):82-99. https://doi.org/10.1053/j.ackd.2006.10.001
  • 28. Curtin RB, Bultman DC, Thomas-Hawkins C, Walters BAJ, Schatell D. Hemodialysis patients' symptom experiences: Effects on physical and mental functioning. Nephrol Nurs J [Internet]. 2002[cited 2024 Apr 12];29(6):562-98. Available from: https://pubmed.ncbi.nlm.nih.gov/12596605/
  • 29. Caplin B, Kumar S, Davenport A. Patients’ perspective of haemodialysis-associated symptoms. Nephrol Dial Transplant. 2011;26(8):2656–63. https://doi.org/10.1093/ndt/gfq763
  • 30. Moledina DG, Perry Wilson F. Pharmacologic treatment of common symptoms in dialysis patients: A narrative review. Semin Dialysis. 2015;28(4):377-83. https://doi.org/10.1111/sdi.12378
  • 31. Amro A, Waldum B, Dammen T, Miaskowski C, & Os I. Symptom clusters in patients on dialysis and their association with quality of life outcomes. J Ren Care. 2014;40(1):23-33. https://doi.org/10.1111/jorc.12051
  • 32. Joshwa B, Campbell ML. Fatigue in patients with chronic kidney disease: Evidence and measures. Nephrol Nurs J [Internet]. 2017[cited 2024 Apr 12];44(4):337-43. Available from: https://pubmed.ncbi.nlm.nih.gov/29160968/
  • 33. Zadrazil J, Horak P. Pathophysiology of anemia in chronic kidney diseases: A review. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2015;159(2),197-202. https://doi.org/10.5507/bp.2013.093
  • 34. Kalantar-Zadeh K, Ficociello LH, Bazzanella J, Mullon C, Anger MS. Slipping through the pores: Hypoalbuminemia and albumin loss during hemodialysis. Int J Nephrol Renovasc Dis. 2021;11-21. https://doi.org/10.2147/IJNRD.S291348 35. Zhang X, Bansal N, Go AS, Hsu CY. Gastrointestinal symptoms, inflammation and hypoalbuminemia in chronic kidney disease patients: A cross-sectional study. BMC Nephrol. 2015;16:1-8. https://doi.org/10.1186/s12882-015-0209-z
  • 36. Hu X, Sang Y, Yang M, Chen X, Tang W. Prevalence of chronic kidney disease-associated pruritus among adult dialysis patients: A meta-analysis of cross-sectional studies. Medicine (Baltimore). 2018;97(21):e10633. https://doi.org/10.1097/MD.0000000000010633. 37. Xie Q, Hu N, Chen Y. Chronic kidney disease-associated pruritus significantly impacts on quality of life of patients on haemodialysis and associates with increased levels of serum calcium and phosphorus. Postgrad Med J. 2022;98(1161):e16. https://doi.org/10.1136/postgradmedj-2020-139688
  • 38. Gatmiri SM, Mahdavi-Mazdeh M, Lessan-Pezeshki M, Abbasi M. Uremic pruritus and serum phosphorus level. Acta Med Iran [Internet]. 2013 [cited 2024 Apr 12];51(7):477-81. Avaible from: https://pubmed.ncbi.nlm.nih.gov/23945893/
  • 39. Pisoni RL, Gillespie BW, Dickinson DM, Chen K, Kutner MH, Wolfe RA. The Dialysis Outcomes and Practice Patterns Study (DOPPS): Design, data elements, and methodology. Am J Kidney Dis. 2004;44(5):7-15. https://doi.org/10.1053/j.ajkd.2004.08.005 40. You AS, Kalantar SS, Norris KC, Peralta RA, Narasaki Y, Fischman R, Rhee CM. Dialysis symptom index burden and symptom clusters in a prospective cohort of dialysis patients. J Nephrol. 2022; 35(5): 1427-36. https://doi.org/10.1007/s40620-022-01313-0

The Relationship Between Dialysis Adequacy and The Symptoms Experienced in Patients Under Hemodialysis Treatment

Yıl 2024, , 43 - 52, 31.05.2024
https://doi.org/10.47565/ndthdt.2024.81

Öz

Aim: This study aimed to examine the relationship between the symptoms experienced by patients receiving hemodialysis treatment and dialysis adequacy.
Materials and Methods: This cross-sectional descriptive study was conducted with 109 patients between April 2023 and January 2024. The Patient Data Collection Form and Dialysis Symptom Index were used for data collection. Dialytic agent clearance and urea reduction rate were used to determine the dialysis adequacy.
Results: The average age of the patients was 62.06±12.75 years, and the mean Dialysis Symptom Index score was 22.26±13.58. The mean dialytic agent clearance levels of the patients was 1.71±0.34. The mean urea reduction rate was 73.49±8.64%. The most common (81.7%) and severe (2.01±1.23) symptom experienced by hemodialysis patients was feeling tired. There was a negative relationship between the average Dialysis Symptom Index scores and hemoglobin levels (r=-0,231; p=0.01), albumin levels (r=-0.223; p=0.02), and a positive relationship between phosphorus levels (r=0.190; p=0.48) of patients. There was no relationship between the patients' average Dialysis Symptom Index score and Dialytic agent clearance and urea reduction rate values (p>0.05).
Conclusion: The symptoms experienced by hemodialysis patients were low in severity and high in frequency. The most common and severe symptom experienced by the patients was feeling tired. As the patients'’hemoglobin and albumin levels decreased, the symptoms experienced by the patients increased. No relationship was found between symptoms experienced by patients and dialysis adequacy. The frequency of symptoms experienced by patients was high, even though dialysis was sufficient. It is recommended that healthcare professionals systematically and routinely monitor patients' symptoms.

Kaynakça

  • 1. Süleymanlar G, Utaş C, Arinsoy T, Ateş K, Altun B, Altiparmak MR, ve ark. A population based survey of chronic renal disease in Turkey the CREDIT study. Nephrol Dial Transplant. 2011;26(6):1862-71. https://doi.org/10.1093/ndt/gfq656
  • 2. Varol E, Sivrikaya SK. Kronik böbrek yetmezliğinde yaşam kalitesi ve hemşirelik. DÜ Sağlık Bil Enst Derg [Internet].
  • 2018[cited 2024 Apr 15];8(3):969-76 Available from: https://dergipark.org.tr/tr/download/article-file/504947 3. Abeywickrama HM, Wimalasiri S, Koyama Y, Uchiyama M, Shimizu U, Kakihara N, Chandrajith R, Nanayakkara N. Quality of Life and symptom burden among chronic kidney disease of uncertain etiology (CKDu) patients in Girandurukotte, Sri Lanka. Int. J. Environ. Res. Public Health . 2020;17(11):4041. https://doi.org/10.3390/ijerph17114041
  • 4. Horigan AE, Schneider SM, Docherty S, Barroso J. The experience and self management of fatigue in hemodialysis patients. Nephrol Nurs J [Internet]. 2013[cited 2024 Apr 10];40(2):113-23. Available from: https://www.ncbi.nlm.nih.gov/pmc/ articles/PMC3703392/
  • 5. Şanlıtürk D, Ovayolu N, Kes D. Hemodiyaliz hastalarında sık karşılaşılan problemler ve çözüm önerileri. Nefro Hem Dergi [Internet]. 2013[cited 2024 Apr 10];1(13):17-25. Available from: https://dergipark.org.tr/tr/pub/hemsire/issue/34384/363161
  • 6. Bossola M, Pepe G, Picca A, Calvani R, Marzetti E. Treating symptoms to improve the quality of life in patients on chronic hemodialysis. Int Urol Nephrol. 2019;51(5):885-87. https://doi.org/10.1007/s11255-019-02121-5
  • 7. Horigan AE. Fatigue in hemodialysis patients: A review of current knowledge. J Pain Symptom Manage. 2012;44(5):715-24. https://doi.org/10.1016/j.jpainsymman.2011.10.015
  • 8. Zedelenmez A, Çağlar M. Hemodiyaliz hastalarında yeterli diyaliz en doğru nasıl değerlendirilir? Nefro Hem Dergi [Internet]. 2019[cited 2024 Apr 10];14(2):70-4. Available from: https://dergipark.org.tr/tr/pub/hemsire/issue/45515/497885
  • 9. Evrenkaya TR, Atasoyu M, Ünver S, Gültepe M, Narin Y, Tülbek Y. Hemodiyaliz yeterliliği ile komorbid faktörler arasındaki ilişki. Türk Nefroloji Diyaliz ve Transplantasyon Dergisi [Internet]. 2002[cited 2024 Apr 10];ll(l):44-51. Available from: https://turkjnephrol.org/Content/files/sayilar/385/44-51.pdf
  • 10. Kalender N, Tosun N. Determination of the relationship between adequacy of dialysis and quality of life and selfcare agency. J Clin Nurs. 2014;23(5–6):820–28. https://doi.org/10.1111/jocn.12208 11. Daugirdas JT. Second generation logarithmic estimates of single-pool variable volume Kt/V: An analysis of error. J Am Soc Nephrol. 1993;4(5):1205-13. https://doi.org/10.1681/ASN.V451205
  • 12. Hemodialysis Adequacy 2006 Work Group, Clinical practice guidelines for hemodialysis adequacy, update 2006. Am J Kidney Dis. 2006;48(1):2-90. https://doi.org/10.1053/j.ajkd.2006.03.051.
  • 13. Stolic RV, Trajkovic GZ, Jekic D, Sovtic SR, Jovanovic AN, Stolic DZ, et al. Predictive parameters of survival in hemodialysis patients with restless leg syndrome. Saudi J Kidney Dis Transpl. 2014;25(5):74-80. https://doi.org/10.4103/1319-2442.139869
  • 14. Yapa HE, Purtell L, Chambers S, & Bonner A. The relationship between chronic kidney disease, symptoms and healthrelated quality of life: A systematic review. J Ren Care. 2020;46(2):74-84. https://doi.org/10.1111/jorc.12303
  • 15. Dikmen RD, Aslan H. The effects of the symptoms experienced by patients undergoing hemodialysis treatment on their comfort levels. J Clin Nephrol Ren Care. 2020;6(2):1-9. https://doi.org/10.23937/2572-3286/1510060
  • 16. Ozen N, Cepken T, Sousa CN. Does adequate hemodialysis prevent symptoms?: A national cross-sectional survey. Clin Nurs Res. 2021;30:334–42. https://doi.org/10.1177/1054773820913986
  • 17. Karaaslan T, Pembegul I. Relationship between symptom burden and dialysis adequacy in patients with chronic kidney disease undergoing hemodialysis. North Clin Istanb. 2023;10(4):435-43. https://doi.org/10.14744/nci.2023.01799.
  • 18. Weisbord SD, Fried LF, Arnold RM, Rotondi AJ, Fine MJ, Levenson DJ, et al. Development of a symptom assessment instrument for chronic hemodialysis patients: The dialysis symptom index. J Pain Symptom Manag. 2004;27(3):226-40. https://doi.org/10.1016/j.jpainsymman.2003.07.004
  • 19. Önsöz HB, Usta Yeşilbalkan O. Reliability and validity of the Turkish version of the dialysis symptom index in chronic hemodialysis patients. Turk Neph Dial Transpl. 2013; 22(1):60-7. https://doi.org/10.5262/tndt.2013.1001.08
  • 20. Chaiviboontham S, Phinitkhajorndech N, Tiansaard J. Symptom clusters in patients with end-stage renal disease undergoing hemodialysis. J Nephrol Renovasc Dis. 2020;297-305. https://10.2147/IJNRD.S271619
  • 21. Siriwardana AN, Hoffman AT, Brennan FP, Li K, Brown MA. Impact of renal supportive care on symptom burden in dialysis patients: A prospective observational cohort study. J Pain Symptom Manage. 2020;60(4):725-36. https://doi.org/10.1016/j .jpainsymman.2020.04.030
  • 22. Alkın Demir C, Özer Z. Hemodiyaliz tedavisi alan hastalarda semptom ve konfor ilişkisi. Nefro Hem Dergi. 2022;17(1):10-27. https://doi.org/10.47565/ndthdt.2022.49
  • 23. Akgöz N, Arslan S, Hemodiyaliz tedavisi alan hastalarda yaşanan semptomların incelenmesi. Nefro Hem Dergi [Internet]. 2017 [cited 2024 Apr 10];12(1):20–8. Available from: https://dergipark.org.tr/tr/download/article-file/360008
  • 24. Zamanian H, Kharameh ZT. Translation and psychometric properties of the persian version of the dialysis symptom ındex in hemodialysis patients. Nephro Urol Mon. 2015;7(1):e23152. https://doi.org/10.5812/numonthly.23152
  • 25. Karasneh R, Al-Azzam S, Altawalbeh SM et al. Predictors of symptom burden among hemodialysis patients: A cross-sectional study at 13 hospitals. Int Urol Nephrol. 2020;52(5):959-67. https://doi.org/10.1007/s11255-020-02458-2
  • 26. Özkan İ, Taylan, S. Investigación sobre la relación entre síntomas observados en pacientes en hemodiálisis con la adecuación de diálisis y rasgos de personalidad. Rev Nefrol Dial Traspl [Internet].2020 [cited 2024 Apr 8];40(2):106-18. Available from: https://www.revistarenal.org.ar/index.php/rndt/article/view/520/1014
  • 27. Murtagh FE, Addington-Hall J, Higginson IJ. The prevalence of symptoms in end-stage renal disease: A systematic review, Adv Chronic Kidney Dis. 2007;14(1):82-99. https://doi.org/10.1053/j.ackd.2006.10.001
  • 28. Curtin RB, Bultman DC, Thomas-Hawkins C, Walters BAJ, Schatell D. Hemodialysis patients' symptom experiences: Effects on physical and mental functioning. Nephrol Nurs J [Internet]. 2002[cited 2024 Apr 12];29(6):562-98. Available from: https://pubmed.ncbi.nlm.nih.gov/12596605/
  • 29. Caplin B, Kumar S, Davenport A. Patients’ perspective of haemodialysis-associated symptoms. Nephrol Dial Transplant. 2011;26(8):2656–63. https://doi.org/10.1093/ndt/gfq763
  • 30. Moledina DG, Perry Wilson F. Pharmacologic treatment of common symptoms in dialysis patients: A narrative review. Semin Dialysis. 2015;28(4):377-83. https://doi.org/10.1111/sdi.12378
  • 31. Amro A, Waldum B, Dammen T, Miaskowski C, & Os I. Symptom clusters in patients on dialysis and their association with quality of life outcomes. J Ren Care. 2014;40(1):23-33. https://doi.org/10.1111/jorc.12051
  • 32. Joshwa B, Campbell ML. Fatigue in patients with chronic kidney disease: Evidence and measures. Nephrol Nurs J [Internet]. 2017[cited 2024 Apr 12];44(4):337-43. Available from: https://pubmed.ncbi.nlm.nih.gov/29160968/
  • 33. Zadrazil J, Horak P. Pathophysiology of anemia in chronic kidney diseases: A review. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2015;159(2),197-202. https://doi.org/10.5507/bp.2013.093
  • 34. Kalantar-Zadeh K, Ficociello LH, Bazzanella J, Mullon C, Anger MS. Slipping through the pores: Hypoalbuminemia and albumin loss during hemodialysis. Int J Nephrol Renovasc Dis. 2021;11-21. https://doi.org/10.2147/IJNRD.S291348 35. Zhang X, Bansal N, Go AS, Hsu CY. Gastrointestinal symptoms, inflammation and hypoalbuminemia in chronic kidney disease patients: A cross-sectional study. BMC Nephrol. 2015;16:1-8. https://doi.org/10.1186/s12882-015-0209-z
  • 36. Hu X, Sang Y, Yang M, Chen X, Tang W. Prevalence of chronic kidney disease-associated pruritus among adult dialysis patients: A meta-analysis of cross-sectional studies. Medicine (Baltimore). 2018;97(21):e10633. https://doi.org/10.1097/MD.0000000000010633. 37. Xie Q, Hu N, Chen Y. Chronic kidney disease-associated pruritus significantly impacts on quality of life of patients on haemodialysis and associates with increased levels of serum calcium and phosphorus. Postgrad Med J. 2022;98(1161):e16. https://doi.org/10.1136/postgradmedj-2020-139688
  • 38. Gatmiri SM, Mahdavi-Mazdeh M, Lessan-Pezeshki M, Abbasi M. Uremic pruritus and serum phosphorus level. Acta Med Iran [Internet]. 2013 [cited 2024 Apr 12];51(7):477-81. Avaible from: https://pubmed.ncbi.nlm.nih.gov/23945893/
  • 39. Pisoni RL, Gillespie BW, Dickinson DM, Chen K, Kutner MH, Wolfe RA. The Dialysis Outcomes and Practice Patterns Study (DOPPS): Design, data elements, and methodology. Am J Kidney Dis. 2004;44(5):7-15. https://doi.org/10.1053/j.ajkd.2004.08.005 40. You AS, Kalantar SS, Norris KC, Peralta RA, Narasaki Y, Fischman R, Rhee CM. Dialysis symptom index burden and symptom clusters in a prospective cohort of dialysis patients. J Nephrol. 2022; 35(5): 1427-36. https://doi.org/10.1007/s40620-022-01313-0
Toplam 36 adet kaynakça vardır.

Ayrıntılar

Birincil Dil Türkçe
Konular Dahili Hastalıklar Hemşireliği
Bölüm Makale
Yazarlar

Özlem Özdemir 0000-0002-3897-3890

Yayımlanma Tarihi 31 Mayıs 2024
Gönderilme Tarihi 18 Nisan 2024
Kabul Tarihi 28 Mayıs 2024
Yayımlandığı Sayı Yıl 2024

Kaynak Göster

Vancouver Özdemir Ö. Hemodiyaliz Tedavisi Gören Hastalarda Diyaliz Yeterliliği ile Deneyimledikleri Semptomlar Arasındaki İlişki/ The Relationship Between Dialysis Adequacy and The Symptoms Experienced in Patients Under Hemodialysis Treatment. NefroHemDergi. 2024;19(2):43-52.

Nefroloji Hemşireliği Dergisi/ Journal of Nephrology Nursing Creative Commons Lisansı Creative Commons Atıf-GayriTicari-Türetilemez 4.0 Uluslararası Lisansı ile lisanslanmıştır.