Erkek cinsel sağlığı için doğal afrodisyaklar

Öz

Erkek cinsel sağlığı için bitkisel kaynaklı tedaviler hakkındaki kanıtlar çelişkilidir. Bu standart olmayan sonuçlar, bitki kaynaklı destek ürünlerin farklı prosedürlerle hazırlanıp kullanılmasına ve bu konudaki araştırmaların genellikle hayvan çalışmaları olmasına bağlıdır. Bu çalışmaların sonuçları çoğu kez yeterince güvenli olmayabilir. Çünkü hayvanların temel mekanik ya da içgüdüsel cinsel işlevlerine ne kadar güvenebileceğimiz kuşkuludur. Yohimbin, Larginin ve ginseng hakkında kullanımlarını öneren birçok çalışma olmasına rağmen, iyi dizayn edilmiş randomize kontrollü çalışmaların eksikliği dikkat çekmektedir.. Mevcut objektif verilere göre erkek cinsel sağlığının korunması ve cinsel hastalıklarının tedavisinde doğal afrodizyakların bu gün için yeri bulunmamaktadır

Anahtar Kelimeler

• Doğal afrodizyaklar,erektil disfonksiyon,erkek cinsel sağlığı

Natural aphrodisiacs for male sexual health

Öz

Evidence for herbal treatments for male sexual health is contradictory. This could be due to non-standardized outcomes and different procedures used in the preparation of plant extracts and research into the subject's is usually reliance on animal studies. Therefore, animal studies are not accurate. Because mechanical or instinctive sexual functions of the animals are doubtful how much we can trust. Preliminary research on a few drugs such as yohimbine, L- Arginine and ginseng is encouraging, but well-designed randomized controlled clinical trials are lacking. In the light of objective data, today there is no place for Natural Aphrodisiacs drugs in the treatment of male sexual problem

Anahtar Kelimeler

• Natural Aphrodisiacs,erectile dysfunction,male sexual health

Kaynakça

1. ) Mohr BA, Guay AT, O'Donnell AB, Mc Kinlay JB. Normal bound and nonbound testosterone levels in normally ageing men: results from the Massachusetts. Male Ageing StudyClin Endocrinol (Oxf) 2005; 62: 64–73.
2. ) Bodie J, Lewis J, Schow D, Monga M. Laboratory evaluations of erectile dysfunction: an evidence based approach. J Urol 2003; 169: 2262–4.
3. ) Baytop T: Türkiye'de Bitkiler İle Tedavi, geçmiş ve bugün 2. baskı, Nobel Tıp Kitabevleri 1999; pp.
4. ) Kara H, Aydın S: Cinsel Sorunlar ve Çözüm Yolları. Şen Yayınları 10, Ankara, 2002.
5. ) Gürkan E, Öndersev DV, Ulusoylu M, Göztaş Z, Şahin N. Bitkisel Tedavi. Marmara Üniversitesi Eczacılık Fakültesi Yayın No: 19, İstanbul 2003.
6. ) Çubukçu B, Meriçli AH, Mat A, Sarıyar G, Sütlüpınar N, Meriçli F. Fitoterapi. İ.Ü. Eczacılık Fakültesi Yayın No: 79, İstanbul, 2002.
7. ) Harnack LJ, Rydell SA, Stang J. Prevalence of use of herbal products by adults in the Minneapolis/St Paul, Minn, metropolitan area. Mayo Clin Proc 2001; 76: 688–94.
8. ) Tamler R, Mechanick JI. Dietary Supplements and Nutraceuticals in the Management of Andrologic Disorders. Endocrinol Metab Clin North Am. 2007; 36: 533–52.

9. ) Hanefi Özbek. Cinsel ve Jinekolojik Sorunların Tedavisinde Bitkilerin Kullanımı. Van Tıp Dergisi ; 12: 170–4. ) Shamloul R. Natural aphrodisiacs. Sex Med ; 7: 39–49. ) Adimoelja A. Phytochemicals and the breakthrough of traditional herbs in the management of sexual dysfunctions. Int J Androl ; 23: 82–4. ) Davis T. H, Aphrodite. Historical Background. University of Pennsylvania Press 1985: 19: –110.
10. ) Maud Kamatenesi-Mugisha , Hannington Oryem-Origa. Traditional herbal remedies used in the management of sexual impotence and erectile dysfunction in western Uganda African Health Sciences 2005; 5: 40- 49.
11. ) Gauthaman K, Adaikan PG, Prasad RN. Aphrodisiac properties of Tribulus Terrestris extract (Protodioscin) in normal and castrated rats. Life Sci ; 71: 1385–96.
12. ) Adaikan PG, Gauthaman K, Prasad RN, Ng SC. Proerectile pharmacological effects of Tribulus terrestris extract on the rabbit corpus cavernosum. Ann Acad Med Singapore 2000; 29: 22–6.
13. ) Kernohan AF, McIntyre M, Hughes DM, Tam SW, Worcel M, Reid JL.An oral yohimbine/L-arginine combination (NMI 861) for the treatment of male erectile dysfunction: a pharmacokinetic, pharmacodynamic and interaction study with intravenous nitroglycerine in healthy male subjects. Br J Clin Pharmacol 2005; 59: 85–93.
14. ) Lebret T, Hervé JM, Gorny P, Worcel M, Botto H. Efficacy and safety of a novel combination of L- arginine glutamate and yohimbine hydrochloride: a new oral therapy for erectile dysfunction. Eur Urol ; 41: 608–13. ) Ang HH, Ngai TH, Tan TH. Effects of Eurycoma longifolia Jack on sexual qualities in middle aged male rats. Phytomedicine 2003; 10: 590–3.
15. ) Ang HH, Cheang HS: Effects of Eurycoma longifolia jack on laevator ani muscle in both uncastrated and testosterone-stimulated castrated intact male rats. Arch Pharm Res 2001; 24: 437–40.
16. ) Ang HH, Ngai TH: Aphrodisiac evaluation in noncopulator male rats after chronic administration of Eurycoma longifolia Jack. Fundam Clin Pharmacol 2001; 15: 265–8.
17. ) Ang HH, Ikeda S, Gan EK: Evaluation of the potency activity of aphrodisiac in Eurycoma longifolia Jack. Phytother Res 2001; 15: 435–6.
18. ) Enrico de Andrade, Alexandre A. de Mesquita, Joaquim de Almeida Claro , Priscila M. de Andrade, Study of the efficacy of Korean Red Ginseng in the treatment of erectile dysfunction. Asian J Androl ; 9: 241–4 ) Jyoti Shah, Herbal Treatments for Erectile Dysfunction, Verlag Berlin Heidelberg 2009.
19. ) Gonzales GF, Cordova A, Gonzales C, Chung A, Vega K, Villena A. Lepidium meyenii (Maca) improved semen parameters in adult men, Asian J Androl 2001; : 301–3.
20. ) Gonzales GF, Córdova A, Vega K, Chung A, Villena A, Góñez C, Castillo S. Effect of Lepidium meyenii (MACA) on sexual desire and its absent relationship with serum testosterone levels in adult healthy men. Andrologia 2002; 34: 367–72.
21. ) Lentz A, Gravitt K, Carson CC, Marson L. Acute and chronic dosing of Lepidium meyenii (Maca) on male rat sexual behavior. J Sex Med 2007; 4: 332–9.
22. ) Zenico T, Cicero AF, Valmorri L, Mercuriali M, Bercovich E. Subjective effects of Lepidium meyenii (Maca) extract on well-being and sexual performances in patients with mild erectile dysfunction: a randomised, double-blind clinical trial. Andrologia. 2009; 41: 95–9.
23. ) Ashton AK, Ahrens K, Gupta S, Masand PS. Antidepressant-induced sexual dysfunction and Ginkgo Biloba. Am J Psychiatry,2000; 157: 836–7.
24. ) Klotz T, Mathers MJ, Braun M, Bloch W, Engelmann U. Effectiveness of oral L-arginine in first- line treatment of erectile dysfunction in a controlled crossover study. Urol Int1999; 63: 220–3. Saka M
25. ) Tüzün A, Ateş Y, Bağci S, Karaeren N, Dağalp K. Acute pancreatitis possibly due to arginine use: a case report. Turk J Gastroenterol 2004; 15: 56–8.
26. ) Tian L, Xin ZC, Yuan YM, Fu J, Liu WJ, Wang LL. Effects of icariin on intracavernosal pressure and systematic arterial blood pressure of rat. Zhonghua Yi Xue Za Zhi 2004; 84: 142–5.
27. ) Xin ZC, Kim EK, Tian L, Lin GT, Icariin on relaxation effect of corpus cavernozum smooth muscle Chin Sci Bull 2001; 46: 1186–90.
28. ) Xin ZC, Kim EK, Lin CS, Liu WJ, Tian L, Yuan YM, Fu J. Effects of icariin on cGMP-specific PDE5 and cAMP-specific PDE4 activities. Asian J Androl. 2003; : 15–8.