Transgenerasyonel Travma: Travmatik Deneyimlerin Epigenetik ve Psikososyal Aktarımı

Öz

Bu çalışma, transgenerasyonel travmanın biyolojik ve psikososyal aktarım süreçlerini inceleyerek, travmatik deneyimlerin yalnızca bireysel düzeyle sınırlı kalmayabileceğini; aksine kuşaklar boyunca etkilerini sürdürebileceğini ortaya koymaktadır. Epigenetik araştırmalar, özellikle DNA metilasyonu, histon modifikasyonları ve mikroRNA düzenlemeleri gibi mekanizmaların, travmanın biyolojik düzeyde kalıcı etkiler bırakma potansiyeline sahip olabileceğini göstermektedir. Psikososyal açıdan ise aile dinamikleri, ebeveyn-çocuk ilişkilerinde bağlanma biçimleri, sosyal öğrenme süreçleri ve kolektif bellek (toplumsal hafızada saklı ortak anlatılar), travmanın transgenerasyonel aktarımını anlamada önemli bir rol oynayabilir. Holokost mağdurları, savaş gazileri, göçmenler ve marjinal topluluklar üzerine yapılan araştırmalar, travmanın hem biyolojik hem de psikososyal düzeyde uzun vadeli etkiler yaratabileceğine dair bulgular sunmaktadır. Psikoterapötik müdahaleler kapsamında bilişsel davranışçı terapi (CBT), göz hareketleriyle duyarsızlaştırma ve yeniden işleme (EMDR), farkındalık temelli yaklaşımlar ve aile terapileri, travma sonrası semptomların hafifletilmesinde faydalı olabilmektedir. Ancak bu yöntemlerin epigenetik düzeydeki etkileri henüz sınırlı biçimde incelenmiştir ve bu alanda daha fazla araştırmaya ihtiyaç duyulmaktadır. Sonuç olarak, transgenerasyonel travmanın incelenmesinde biyolojik ve psikososyal boyutların birlikte ele alınmasını sağlayan bütüncül yaklaşımlara duyulan gereksinim devam etmektedir. Gelecekte yapılacak araştırmalarda, psikoterapötik müdahalelerin olası epigenetik etkilerinin yanı sıra kültürel bağlamların ve toplumsal süreçlerin de ayrıntılı biçimde ele alınması, literatüre daha kapsamlı katkılar sağlayabilir.

Anahtar Kelimeler

• transgenerasyonel travma
• epigenetik
• psikososyal aktarım
• psikoterapi

Transgenerational Trauma: Epigenetic and Psychosocial Transmission of Traumatic Experiences

Öz

This study explores the biological and psychosocial pathways of transgenerational trauma, proposing that traumatic experiences may not be confined to the individual but could potentially affect future generations. Epigenetic research suggests that mechanisms like DNA methylation, histone modifications, and microRNA regulation might contribute to the ongoing presence of trauma at the biological level. From a psychosocial standpoint, family dynamics, parent-child attachment patterns, social learning, and collective memory—shared narratives stored within societal memory—may be crucial in understanding how trauma is transmitted across generations. Studies involving Holocaust survivors, war veterans, migrants, and marginalized groups show evidence that trauma can produce long-lasting effects at both biological and psychosocial levels. Psychotherapeutic approaches such as cognitive-behavioral therapy (CBT), eye movement desensitization and reprocessing (EMDR), mindfulness-based techniques, and family therapy may help reduce post-traumatic symptoms. Nevertheless, the influence of these therapies on epigenetic mechanisms is still under-investigated, highlighting the need for further research. Overall, there is a clear need for integrated methods that consider both biological and psychosocial factors in studying transgenerational trauma. Future research should examine the potential epigenetic effects of psychotherapeutic treatments and consider cultural and societal influences to gain a more complete understanding of this complex phenomenon.

Anahtar Kelimeler

• transgenerational trauma
• epigenetics
• psychosocial transmission
• psychotherapy.

Kaynakça

1. Alexander, J. C. (2004). Toward a theory of cultural trauma. In J. C. Alexander, R. Eyerman, B. Giesen, N. J. Smelser, & P. Sztompka (Eds.), Cultural trauma and collective identity (pp. 1–30). Berkeley: University of California Press.
2. Alexander, J. C. (2012). Trauma: A social theory. Polity Press.
3. American Psychiatric Association. (2013). Diagnostic and statistical manual of mental disorders (5th ed.). American Psychiatric Association. https://doi.org/10.1176/appi.books.9780890425596
4. American Psychological Association. (2020). Publication manual of the American Psychological Association (7th ed.). American Psychological Association. https://doi.org/10.1037/0000165-000
5. Bakalian, A., & Medzian, K. (2021). Collective trauma and memory: Armenian genocide narratives in the diaspora. Genocide Studies International, 14(2), 158–176. https://doi.org/10.3138/gsi-2020-0020
6. Bandura, A. (1977). Social learning theory. Prentice Hall.
7. Bandura, A. (1986). Social foundations of thought and action: A social cognitive theory. Prentice Hall.
8. Banushi, B., Collova, J., & Milroy, H. (2025). Epigenetic echoes: Bridging nature, nurture, and healing across generations. International Journal of Molecular Sciences, 26(7), 3075. https://doi.org/10.3390/ijms26073075

9. Bhugra, D., & Becker, M. A. (2005). Migration, cultural bereavement and cultural identity. World Psychiatry, 4(1), 18–24. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1414713/
10. Bisson, J. I., Cosgrove, S., Lewis, C., & Roberts, N. P. (2021). Post-traumatic stress disorder. BMJ, 372, n94. https://doi.org/10.1136/bmj.n94
11. Boszormenyi-Nagy, I., & Spark, G. M. (1973). Invisible loyalties: Reciprocity in intergenerational family therapy. Harper & Row.
12. Bowen, M. (1978). Family therapy in clinical practice. Jason Aronson.
13. Bowers, M. E., & Yehuda, R. (2016). Intergenerational transmission of stress in humans. Neuropsychopharmacology, 41(1), 232–244. https://doi.org/10.1038/npp.2015.247
14. Bowlby, J. (1969). Attachment and loss: Vol. 1. Attachment. Basic Books.
15. Bowlby, J. (1988). A secure base: Parent-child attachment and healthy human development. Basic Books. Branje, S., Geeraerts, S., de Zeeuw, E. L., Oerlemans, A. M., Koopman-Verhoeff, M. E., Schulz, S., & Boomsma, D. I. (2020). Intergenerational transmission: Theoretical and methodological issues and an introduction to four Dutch cohorts. Developmental Cognitive Neuroscience, 45, 100835. https://doi.org/10.1016/j.dcn.2020.100835
16. Brescó de Luna, I. (2022). Collective memory and trauma in contemporary societies: Narratives, politics, and practices. Springer.
17. Briere, J., & Scott, C. (2022). Principles of trauma therapy: A guide to symptoms, evaluation, and treatment (3rd ed.). Sage Publications.
18. Brisch, K. H. (2021). Treating attachment disorders: From theory to therapy (2nd ed.). Guilford Press.
19. Cassidy, J., & Shaver, P. R. (Eds.). (2016). Handbook of attachment: Theory, research, and clinical applications (3rd ed.). Guilford Press.
20. Chan, Y. S., & Gurdon, J. B. (2021). Nuclear reprogramming and the epigenetic memory of the germline. Nature Reviews Molecular Cell Biology, 22(7), 437–454. https://doi.org/10.1038/s41580-021-00342-7
21. Cicchetti, D., & Toth, S. L. (1995). A developmental psychopathology perspective on child abuse and neglect. Journal of the American Academy of Child & Adolescent Psychiatry, 34(5), 541–565. https://doi.org/10.1097/00004583-199505000-00008
22. Cicchetti, D., & Toth, S. L. (2005). Child maltreatment. Annual Review of Clinical Psychology, 1, 409–438. https://doi.org/10.1146/annurev.clinpsy.1.102803.144029
23. Cohen, J. A., Mannarino, A. P., & Deblinger, E. (2017). Treating trauma and traumatic grief in children and adolescents (2nd ed.). Guilford Press.
24. Crittenden, P. M., & Landini, A. (2011). Assessing adult attachment: A dynamic-maturational approach to discourse analysis. W. W. Norton & Company.
25. Danieli, Y. (1998). Intergenerational aspects of trauma and their impact on trust and distrust. Psychoanalytic Inquiry, 18(2), 124–139. https://doi.org/10.1080/07351699809534255
26. DeGruy, J. (2005). Post traumatic slave syndrome: America’s legacy of enduring injury and healing. Upton Press.
27. Dias, B. G., & Ressler, K. J. (2014). Parental olfactory experience influences behavior and neural structure in subsequent generations. Nature Neuroscience, 17(1), 89–96. https://doi.org/10.1038/nn.3594
28. El-Khalil, C., Caculidis-Tudor, D., & Nedelcea, C. (2025). Impact of intergenerational trauma on second-generation descendants: A systematic review. BMC Psychology, 13(1), 668. https://doi.org/10.1186/s40359-025-03012-4
29. Eyerman, R. (2019). Memory, trauma, and identity. Palgrave Macmillan. https://doi.org/10.1007/978-3-030-13507-2
30. Fearon, R. M. P., & Roisman, G. I. (2017). Attachment security and mental health: A meta-analysis. Psychological Bulletin, 143(3), 234–266. https://doi.org/10.1037/bul0000084
31. Felitti, V. J., Anda, R. F., Nordenberg, D., Williamson, D. F., Spitz, A. M., Edwards, V., Koss, M. P., & Marks, J. S. (1998). Relationship of childhood abuse and household dysfunction to many of the leading causes of death in adults: The Adverse Childhood Experiences (ACE) study. American Journal of Preventive Medicine, 14(4), 245–258. https://doi.org/10.1016/S0749-3797(98)00017-8
32. Figley, C. R. (1995). Compassion fatigue: Coping with secondary traumatic stress disorder in those who treat the traumatized. Routledge.
33. Fonagy, P., Gergely, G., Jurist, E. L., & Target, M. (2002). Affect regulation, mentalization, and the development of the self. Other Press.
34. Fraley, R. C., & Roisman, G. I. (2018). The development of adult attachment: A longitudinal perspective. Current Opinion in Psychology, 25, 1–6. https://doi.org/10.1016/j.copsyc.2018.02.019
35. Franklin, T. B., Russig, H., Weiss, I. C., Gräff, J., Linder, N., Michalon, A., Vizi, S., & Mansuy, I. M. (2010). Epigenetic transmission of the impact of early stress across generations. Biological Psychiatry, 68(5), 408–415. https://doi.org/10.1016/j.biopsych.2010.05.036
36. Gapp, K., & Bohacek, J. (2020). Epigenetic germline inheritance in mammals: Looking to the past to understand the future. Science Advances, 6(8), eaaz7603. https://doi.org/10.1126/sciadv.aaz7603 Gapp, K., & Bohacek, J. (2023). Epigenetic inheritance of trauma and resilience: Insights from animal models. Trends in Molecular Medicine, 29(2), 143–157. https://doi.org/10.1016/j.molmed.2022.12.005
37. Gapp, K., Bohacek, J., & Mansuy, I. M. (2014). Transgenerational epigenetic inheritance of trauma effects. Trends in Neurosciences, 37(9), 491–505. https://doi.org/10.1016/j.tins.2014.05.003
38. Hatfield, E., Cacioppo, J. T., & Rapson, R. L. (1994). Emotional contagion. Cambridge University Press. Heard, E., & Martienssen, R. A. (2021). Transgenerational epigenetic inheritance: Myths and mechanisms. Cell, 184(7), 1681–1697. https://doi.org/10.1016/j.cell.2021.01.053
39. Herman, J. L. (1992). Trauma and Recovery: The aftermath of violence—from domestic abuse to political terror. Basic Books.
40. Herman, J. L. (1997). Trauma and recovery: The aftermath of violence—from domestic abuse to political terror (2nd ed.). Basic Books.
41. Hirsch, M. (2008). The generation of postmemory. Poetics Today, 29(1), 103–128. https://doi.org/10.1215/03335372-2007-019
42. Hirschberger, G. (2018). Collective trauma and the social construction of meaning. Frontiers in Psychology, 9, 1441. https://doi.org/10.3389/fpsyg.2018.01441
43. Hölzel, B. K., Lazar, S. W., Gard, T., Schuman-Olivier, Z., Vago, D. R., & Ott, U. (2011). How does mindfulness meditation work? Proposing mechanisms of action from a conceptual and neural perspective. Perspectives on Psychological Science, 6(6), 537–559. https://doi.org/10.1177/1745691611419671
44. Issa, J. P. J., Smith, R., & Thompson, C. (2022). Challenges in clinical epigenetic studies: Methodological considerations. Epigenomics, 14(12), 985–1002. https://doi.org/10.2217/epi-2022-0011
45. Issa, J. P., Baylin, S. B., & Jones, P. A. (2022). A critical appraisal of clinical epigenetics: Future directions and challenges. Clinical Epigenetics, 14, 92. https://doi.org/10.1186/s13148-022-01315-6
46. Jans, D. C., Ladd-Acosta, C., Feinberg, A. P., & Fallin, M. D. (2021). Epigenetic mechanisms in intergenerational transmission of health and disease. Nature Reviews Genetics, 22(11), 687–700. https://doi.org/10.1038/s41576-021-00416-2
47. Jawaid, A., & Mansuy, I. M. (2019). Inter- and transgenerational inheritance of behavioral phenotypes. Current Opinion in Behavioral Sciences, 25, 96–101. https://doi.org/10.1016/j.cobeha.2018.12.002
48. Johnson, S. M. (2004). The practice of emotionally focused couple therapy: Creating connection. Routledge.
49. Kabat-Zinn, J. (1990). Full catastrophe living: Using the wisdom of your body and mind to face stress, pain, and illness. Delta.
50. Kellermann, N. P. (2001). Transmission of Holocaust trauma: An integrative view. Psychiatry, 64(3), 256–267. https://doi.org/10.1521/psyc.64.3.256.18464
51. Kellermann, N. P. F. (2015). Epigenetic transmission of Holocaust trauma: Can nightmares be inherited? Annals of the New York Academy of Sciences, 1338(1), 142–152. https://doi.org/10.1111/nyas.12679
52. Kira, I. A., Lewandowski, L., Somers, C. L., Yoon, J., & Chiodo, L. (2013). The effects of trauma types, cumulative trauma, and PTSD on IQ in two highly traumatized adolescent groups. Psychological Trauma: Theory, Research, Practice, and Policy, 5(2), 134–142. https://doi.org/10.1037/a0027653
53. Klibaner-Schiff, E., et al. (2024). Environmental exposures influence multigenerational epigenetic transmission. Clinical Epigenetics.
54. Kostova, Z., & Matanova, V. L. (2024). Transgenerational trauma and attachment. Frontiers in Psychology, 15, 1362561. https://doi.org/10.3389/fpsyg.2024.1362561
55. Kuhn, T. S. (1962). The structure of scientific revolutions. University of Chicago Press.
56. Lakatos, I. (1970). Falsification and the methodology of scientific research programmes. In I. Lakatos & A. Musgrave (Eds.), Criticism and the growth of knowledge (pp. 91–196). Cambridge University Press.
57. Liotti, G. (2006). A model of dissociation based on attachment theory and research. Journal of Trauma & Dissociation, 7(4), 55–73. https://doi.org/10.1300/J229v07n04_04
58. Lykes, M. B., Blanche, M. T., & Hamber, B. (1999). Narrating survival and change in Guatemala and South Africa: The politics of representation and a liberatory community psychology. American Journal of Community Psychology, 27(2), 179–209. https://doi.org/10.1023/A:1022888400477
59. Lyons-Ruth, K., Yellin, C., Melnick, S., & Atwood, G. (2006). Childhood experiences of trauma and loss have different relations to maternal unresolved and hostile-helpless states of mind on the AAI. Attachment & Human Development, 8(3), 187–214. https://doi.org/10.1080/14616730600856024
60. Main, M., & Hesse, E. (1990). Parents’ unresolved traumatic experiences are related to infant disorganized attachment status: Is frightened and/or frightening parental behavior the linking mechanism? In M. T. Greenberg, D. Cicchetti, & E. M. Cummings (Eds.), Attachment in the preschool years: Theory, research, and intervention (pp. 161–182). University of Chicago Press.
61. McNally, R. J. (2021). Remembering trauma (20th anniversary ed.). Harvard University Press.
62. Meaney, M. J. (2001). Maternal care, gene expression, and the transmission of individual differences in stress reactivity across generations. Annual Review of Neuroscience, 24, 1161–1192. https://doi.org/10.1146/annurev.neuro.24.1.1161
63. Meaney, M. J. (2010). Epigenetics and the biological definition of gene × environment interactions. Child Development, 81(1), 41–79. https://doi.org/10.1111/j.1467-8624.2009.01381.x
64. Meaney, M. J. (2020). Parental care and the intergenerational transmission of stress responses. Nature Reviews Neuroscience, 21(4), 227–239. https://doi.org/10.1038/s41583-020-0293-6
65. Meaney, M. J., & Szyf, M. (2005). Environmental programming of stress responses through DNA methylation: Life at the interface between a dynamic environment and a fixed genome. Dialogues in Clinical Neuroscience, 7(2), 103–123. https://doi.org/10.31887/DCNS.2005.7.2/mmeaney
66. Mikulincer, M., & Shaver, P. R. (2016). Attachment in adulthood: Structure, dynamics, and change (2nd ed.). Guilford Press.
67. Minuchin, S. (1974). Families and family therapy. Harvard University Press.
68. Moog, N. K., Entringer, S., Rasmussen, J. M., Styner, M., Gilmore, J. H., Kathmann, N., Wadhwa, P. D., & Buss, C. (2018). Intergenerational effect of maternal exposure to childhood maltreatment on newborn brain anatomy. Biological Psychiatry, 83(2), 120–127. https://doi.org/10.1016/j.biopsych.2017.07.009
69. Moore, A., & Reiss, D. (2021). Questioning the epigenetic model of transgenerational trauma: Alternative explanations. Annual Review of Clinical Psychology, 17, 255–276. https://doi.org/10.1146/annurev-clinpsy-081219-093432
70. Murray, H. A. (1943). Thematic Apperception Test manual. Harvard University Press.
71. Nestler, E. J. (2016). Transgenerational epigenetic contributions to stress responses: Fact or fiction? PLOS Biology, 14(3), e1002426. https://doi.org/10.1371/journal.pbio.1002426
72. Norrholm, S. D., & Jovanovic, T. (2018). Fear processing, psychophysiology, and PTSD. Harvard Review of Psychiatry, 26(3), 129–141. https://doi.org/10.1097/HRP.0000000000000189
73. Perez, M. F., & Lehner, B. (2019). Intergenerational and transgenerational epigenetic inheritance in animals. Nature Cell Biology, 21(2), 143–151. https://doi.org/10.1038/s41556-018-0242-9
74. Popper, K. (2005). The logic of scientific discovery (Reprint ed.). Routledge. (Original work published 1934)
75. Porges, S. W. (2021). Polyvagal safety: Attachment, communication, self-regulation. W. W. Norton & Company.
76. Racine, N., Deneault, A. A., Thiemann, R., Turgeon, J., Zhu, J., Cooke, J., & Madigan, S. (2023). Intergenerational transmission of parent adverse childhood experiences to child outcomes: A systematic review and meta-analysis. Child Abuse & Neglect, 106, 106479. https://doi.org/10.1016/j.chiabu.2023.106479
77. Racine, N., Eadie, A., Zhu, J., Pogue, J., Madigan, S., & McDonald, S. (2024). Effects of mindfulness-based interventions on symptoms and interoception in trauma-related disorders: A systematic review and meta-analysis. Journal of Affective Disorders, 356, 345–357. https://doi.org/10.1016/j.jad.2024.04.001
78. Reese, E. M., Barlow, M. J., Dillon, M., Villalon, S., Barnes, M. D., & Crandall, A. (2022). Intergenerational transmission of trauma: The mediating effects of family health. International Journal of Environmental Research and Public Health, 19(10), 5944. https://doi.org/10.3390/ijerph19105944
79. Scaer, R. C. (2005). The trauma spectrum: Hidden wounds and human resiliency. W. W. Norton & Company. Schore, A. N. (2003). Affect regulation and the repair of the self. W. W. Norton & Company.
80. Schore, A. N. (2012). The science of the art of psychotherapy. W. W. Norton & Company.
81. Schore, A. N. (2022). The foundational role of the right brain in attachment and regulation: A commentary on Porges. Infant Mental Health Journal, 43(2), 205–220. https://doi.org/10.1002/imhj.21938
82. Schwarz, E. D., & Perry, B. D. (2020). The post-traumatic self: Restoring meaning and wholeness to personality. W. W. Norton & Company.
83. Schwerdtfeger, K. L., & Goff, B. S. N. (2007). Intergenerational transmission of trauma: Exploring mother–infant prenatal attachment. Journal of Traumatic Stress, 20(1), 39–51. https://doi.org/10.1002/jts.20180
84. Shapiro, F. (1989). Eye movement desensitization: A new treatment for post-traumatic stress disorder. Journal of Behavior Therapy and Experimental Psychiatry, 20(3), 211–217. https://doi.org/10.1016/0005-7967(89)90025-9
85. Shapiro, F. (2017). Eye movement desensitization and reprocessing (EMDR) therapy: Basic principles, protocols, and procedures. Guilford Press.
86. Shapiro, F., & Laliotis, D. (2020). EMDR therapy: Mechanisms, research, and outcomes. Current Directions in Psychological Science, 29(5), 431–437. https://doi.org/10.1177/0963721420940030
87. Siegel, D. J., & Hartzell, M. (2003). Parenting from the inside out: How a deeper self-understanding can help you raise children who thrive. TarcherPerigee.
88. Smelser, N. J. (2020). The social foundations of collective trauma. Annual Review of Sociology, 46, 101–119. https://doi.org/10.1146/annurev-soc-121919-054634
89. Sroufe, L. A. (2020). The development of the person: The Minnesota study of risk and adaptation from birth to adulthood. Guilford Press.
90. Sroufe, L. A. (2020). The place of attachment in human development. Developmental Review, 57, 100927. https://doi.org/10.1016/j.dr.2020.100927
91. van der Kolk, B. A. (1996). Traumatic stress: The effects of overwhelming experience on mind, body, and society. Guilford Press.
92. van der Kolk, B. A. (2014). The body keeps the score: Brain, mind, and body in the healing of trauma. Viking Press.
93. van der Kolk, B. A., McFarlane, A. C., & Weisaeth, L. (Eds.). (1996). Traumatic stress: The effects of overwhelming experience on mind, body, and society. Guilford Press.
94. Volkan, V. D. (1997). Bloodlines: From ethnic pride to ethnic terrorism. Farrar, Straus and Giroux.
95. Weathers, F. W., Blake, D. D., Schnurr, P. P., Kaloupek, D. G., Marx, B. P., & Keane, T. M. (2013). The clinician-administered PTSD scale for DSM-5 (CAPS-5). Psychological Assessment, 25(3), 1063–1078. https://doi.org/10.1037/a0032381
96. Weaver, I. C. G., Cervoni, N., Champagne, F. A., D’Alessio, A. C., Sharma, S., Seckl, J. R., … Meaney, M. J. (2004). Epigenetic programming by maternal behavior. Nature Neuroscience, 7(8), 847–854.
97. Weiss, D. S., & Marmar, C. R. (1997). The Impact of Event Scale—Revised. In J. P. Wilson & T. M. Keane (Eds.), Assessing psychological trauma and PTSD (pp. 399–411). Guilford Press.
98. White, M., & Epston, D. (1990). Narrative means to therapeutic ends. W. W. Norton & Company. Widom, C. S. (1989). The cycle of violence. Science, 244(4901), 160–166. https://doi.org/10.1126/science.270.5239.160
99. Williams, D. R., & Mohammed, S. A. (2009). Discrimination and racial disparities in health: Evidence and needed research. Journal of Behavioral Medicine, 32(1), 20–47. https://doi.org/10.1007/s10865-008-9193-0
100. World Health Organization. (2003). Mental health in emergencies: Mental and social aspects of health of populations exposed to extreme stressors. WHO. https://apps.who.int/iris/handle/10665/42574
101. Yehuda, R., & Bierer, L. M. (2008). Transgenerational transmission of cortisol and PTSD risk. Progress in Brain Research, 167, 121–135. https://doi.org/10.1016/S0079-6123(07)67008-1
102. Yehuda, R., & Lehrner, A. (2018). Intergenerational transmission of trauma effects: Putative role of epigenetic mechanisms. World Psychiatry, 17(3), 243–257. https://doi.org/10.1002/wps.20514
103. Yehuda, R., & Lehrner, A. (2021). Transgenerational transmission of trauma effects: Putting together the pieces of the puzzle. Journal of Psychological Research, 15(3), 45–62.
104. Yehuda, R., Bierer, L. M., Andrew, R., & Schmeidler, J. (2014). Holocaust survivors’ parental PTSD and offspring’s cortisol reactivity. Psychoneuroendocrinology, 48, 1–10. https://doi.org/10.1016/j.psyneuen.2014.06.003
105. Yehuda, R., Daskalakis, N. P., Bierer, L. M., Bader, H. N., Klengel, T., Holsboer, F., & Binder, E. B. (2016). Holocaust exposure induced intergenerational effects on FKBP5 methylation. Biological Psychiatry, 80(5), 372–380. https://doi.org/10.1016/j.biopsych.2015.08.005
106. Yehuda, R., Halligan, S. L., & Bierer, L. M. (2005). Cortisol and memory in posttraumatic stress disorder: A systematic review. Psychoneuroendocrinology, 30(9), 795–804. https://doi.org/10.1016/j.psyneuen.2005.03.008
107. Yunitri, N., Probandari, A., Bai, Y., Schubert, C. F., Morina, N., & Bisson, J. I. (2023). Comparative effectiveness of psychotherapies in adults with post-traumatic stress disorder: A network meta-analysis of randomized controlled trials. Psychological Medicine, 53(16), 1–12. https://doi.org/10.1017/S0033291723000595
108. Zannas, A. S., & West, A. E. (2014). Epigenetics and the regulation of stress vulnerability and resilience. Neuroscience, 264, 157-170. https://doi.org/10.1016/j.neuroscience.2013.12.003