Potential Human Health Risk from Toxic/Carcinogenic Arsenic in Ripe and Unripe Tomatoes Grown in Wastewater Exposed Zone

Yıl 2024, Cilt: 10 Sayı: 1, 89 - 99, 30.06.2024

Murat Topal , Emine Işıl Arslan Topal , Erdal Öbek

https://doi.org/10.29132/ijpas.1430284

Öz

The aim of the present study was to investigate the potential risk to human health from toxic/carcinogenic arsenic in ripe (RiTo) and unripe tomatoes (UnRiTo) grown in the municipal wastewater treatment plant effluents exposure zone. The arsenic concen-trations were determined in each tissue of RiTo and UnRiTo tomatoes. Arsenic values in tomatoes were root>leaf>unripe tomato>ripe tomato>stem. The maximum ED (exposure dose) value in RiTos was 1.21E-02 mg.kg-1.day-1 for child, minimum ED value was 4.80E-03 mg.kg-1.day-1 for male. The ED value was calculated as 5.44E-03 mg.kg-1.day-1 for female. The maximum ED value in UnRiTo was 2.12E-02 mg.kg-1.day-1 for child, min ED value was 8.39-03 mg.kg-1.day-1 for male. ED value was calculated as 9.51E-03 mg.kg-1.day-1 for female. EDs in RiTo and UnRiTo were child>female>male. When the HQs (hazard quotient) in RiTo and UnRiTo compared, HQ values in UnRiTo were higher. All of the HQ values were higher than 1. As a re-sult, results of tomatoes analysis show that there was non-carcinogenic and carcino-genic health risks.

Anahtar Kelimeler

Arsenic, carcinogenic, health risk, tomatoes, wastewater

Kaynakça

• Gunawardena, S.A., Gunawardana, J.W., Chandrajith, R., Thoradeniya, T., Jayasinghe, S. (2020). Renal bioaccumulation of trace elements in urban and rural Sri Lankan populations: A preliminary study based on post mortem tissue analysis, Journal of Trace Elements in Medicine and Biology, 61: Article 126565.
• Anandkumar, A., Li, J., Prabakaran, K., Jia, Z.X., Du, D. (2020). Accumulation of toxic elements in an invasive crayfish species (Procambarus clarkii) and its health risk assessment to humans, Journal of Food Composition and Analysis, 88: Article 103449.
• USEPA, (2004). U.S.E.P.A, Primer for Municipal Wastewater Treatment Systems, US Environ-mental Protection Agency Municipal Support, Division Office.
• Moloi, M., Ogbeide, O., Otomo, P.V. (2020). Probabilistic health risk assessment of heavy metals at wastewater discharge points within the Vaal River Basin, South Africa, International Journal of Hygiene and Environmental Health, 224:Article 113421.
• Edokpayi, J., Odiyo, J., Msagati, T., Popoola, E. (2015). Removal efficiency of faecal indicator organisms, nutrients and heavy metals from a peri-urban wastewater treatment plant in thohoyandou, Limpopo Province, South Africa, Int. J. Environ. Res. Public Health, 12: 7300-7320.
• Mosolloane, P.M., Bredenhand, E., Otomo, P.V. (2019). Laboratory assessment of the ecotoxic effects of sewage sludge from the Maluti-Drakensberg region on a terrestrial oligochaete species, Ecotoxicology, 28:86-91.
• Sun, Z., Hu, Y., Cheng, H. (2020). Public health risk of toxic metal(loid) pollution to the population living near an abandoned small-scale polymetallic mine, Science of The Total Environment, 718:Article 137434.
• Hough, R.L., Breward, N., Young, S.D., Crout, N.M.J., Tye, A.M., Moir, A.M., Thornton, I. (2004). Assessing potential risk of heavy metal exposure from consumption of home-produced vegetables by urban populations, Environ. Health Persp., 112: 215-221.
• Nachman, K.E., Punshon, T., Rardin, L., Signes-Pastor, A.J., Murray, C.J., Karagas, M.R. 2018. Opportunities and challenges for dietary arsenic intervention, Environ. Health Persp., 126: Article 084503.
• Cui, D., Zhang, P., Li, H., Zhang, Z., Yang, Z. (2020). Biotransformation of dietary inorganic arsenic in a freshwater fish Carassius auratus and the unique association between arsenic dimethylation and oxidative damage, Journal of Hazardous Materials, 391: Article 122153.
• Zhao, Y., Zhen, Z., Wang, Z., Zeng, L., Yan, C. (2020). Influence of environmental factors on arsenic accumulation and biotransformation using the aquatic plant species Hydrilla verticillata, Journal of Environmental Sciences, 90: 244-252.
• Bocca, B., Pino, A., Brumatti, L. V., Rosolen, V., Ronfani, L. (2020). Children exposure to inorganic and organic arsenic metabolites: A cohort study in Northeast Italy, Environmental Pollution, 265: 114826.
• Lyu, R., Gao, Z., Li, D., Yang, Z., Zhang, T. (2020). Bioaccessibility of arsenic from gastropod along the Xiangjiang River: Assessing human health risks using an in vitro digestion model, Ecotox-icology and Environmental Safety, 193: Article 110334.
• Manthari, R.K., Tikka, C., Ommati, M.M., Niu, R., Sun, Z., Wang, J. (2018). Arsenic-induced autophagy in the developing mouse cerebellum: involvement of the blood-brain barrier’s tight-junction proteins and the PI3K-Akt-mTOR signaling pathway, J. Agric. Food Chem., 66: 8602-8614.
• Signes-Pastor, A.J., Mitra, K., Sarkhel, S., Hobbes, M., Burlo, F., de Groot,W.T. (2008). Arsenic speciation in food and estimation of the dietary intake of inorganic arsenic in a rural village of West Bengal, India, J. Agric. Food Chem., 56:9469-9474.
• TMAF, (2023). https://arastirma.tarimorman.gov.tr/tepge/Belgeler/PDF%20Tar%C4%B1m%20%C3%9Cr%C3%BCnleri%20Piyasalar%C4%B1/2023-Temmuz%20Tar%C4%B1m%20%C3%9Cr%C3%BCnleri%20Raporu/DOMATES%20T%C3%9CP%20HAZ%C4%B0RAN%202023-TEPGE.pdf.
• TUİK, (2020). Turkish Statistical Institute, 2020. https://www.tuik.gov.tr/ Acessed: 10.11.2020.
• Topal, M. , Aşcı Toraman, Z. , Arslan Topal, E. I. , Sel, C. & Öbek, E. (2021). Investigation of SARS-CoV-2 and gastrointestinal pathogens in a municipal wastewater treatment plant in Turkey . International Journal of Pure and Applied Sciences , 7 (3) , 500-508 . DOI: 10.29132/ijpas.956919.
• Topal, M., Arslan Topal, E.I., (2011). Evaluation of the Elazığ municipal wastewater treatment plant with some parameters in 2010-2011 Winter season, Cumhur. Sci. J., 32: 1-12.
• Topal, M., Uslu, G., Öbek, E., Arslan Topal, E.I., (2014). Evaluation of Elazığ municipal wastewater treatment plant with physicochemical parameters, Eurasia 2014 Waste Management Symposium, p.1169–1176, İstanbul, Turkey.
• Topal, M., Uslu, G., Öbek, E., Arslan Topal, E.I., (2016). Investigation of relationships between removals of tetracycline and degradation products and physicochemical parameters in municipal wastewater treatment plant, Journal of Environmental Management, 173:1-9.
• Lenntech, “Chemical properties of arsenic - Health effects of arsenic - Environmental effects of arsenic” [online document], (2023). Available: https://www.lenntech.com/periodic/elements/as.htm [Accessed: Sep 14, 2023].
• Lian, M.; Wang, J.; Sun, L.; Xu, Z.; Tang, J.; Yan, J.; Zeng, X. (2019). Profiles and potential health risks of heavy metals in soil and crops from the watershed of Xi River in Northeast China. Ecotoxicol. Environ.Saf., 169, 442-448.
• USEPA. (2001). Supplemental Guidance for Developing Soil Screening Levels for Superfund Sites [R]. Office of Solid Waste and Emergency Response, Washington, DC [OSWER9355.4e24].
• USEPA. (2011). United States Environmental Protection Agency. Exposure Factors Handbook. National Center for Environmental Assessment. Washington, DC (EPA/600/R-09/ 052F), https://cfpub.epa.gov/ncea/risk/recordisplay.cfm?deid=236252.
• USEPA. (1989). Risk assessment guidance for Superfund Human health evaluation manual, (part A) [R], vol. 1, Office of emergency and remedial response, Washington, DC (1989) [EPA/540/1-89/002].
• Markert, B. (1992). Establishing of Reference Plant for Inorganic Characterization of Different Plant Species By Chemical Fingerprinting. Water Air Soil Pollut. 64:533-538.
• Bhattacharya, P., Welch, A.H., Stollenwerk, K.G., McLaughlin, M.J., Bundschuh, J., Panaullah, G. (2007). Arsenic in the environment: biology and chemistry, Science of the Total Environment, 379:109-120.
• Naveed, S., Yu, Q., Zhang, C., Ge, Y., (2020). Extracellular polymeric substances alter cell surface properties, toxicity, and accumulation of arsenic in Synechocystis PCC6803, Environmental Pollution, 261:Article 114233.
• Zuzolo, D., Cicchella, D., Demetriades, A., Birke, M. (2020). Arsenic: Geochemical distribution and age-related health risk in Italy, Environmental Research, 182:Article 109076.
• Hsueh, Y.M., Chen, W.J., Lee, C.Y., Chien, S.N., Shiue, H.S., Huang, S.R. (2016). Association of arsenic methylation capacity with developmental delays and health status in children: a prospective case–control trial, Sci. Rep., 6: 37287.