Kayısı Yaprak Özütü ile Sentezlenen Gümüş Nanopartiküllerin Antimikrobiyal Potansiyeli

Yıl 2022, , 50 - 57, 10.03.2022

Ayşe Baran , Özfer Yeşilada

https://doi.org/10.33715/inonusaglik.1012011

Cited By: 2

Öz

Metalik nanopartiküller tıpta önemli maddelerdir. Bu partiküller yeşil sentez dahil çeşitli yollarla üretilebilirler. Gümüş nanopartiküllerin bitki özütleri ile üretimi çevre dostu özelliklerinden dolayı yaygın olarak kullanılmaktadır. Bu çalışmada gümüş nanopartiküller biyolojik yöntemle sentezlenmiş ve Kayısı ağacı (Prunus armeniaca) yaprak özütü redükleyici ajan olarak kullanılmıştır. Renk değişimi ve 400-500 nm’de özgül absorbans piki oluşumu AgNP oluşumunun ilk göstergeleri olmuştur. XRD analizi kristal yapıda partikülleri göstermiştir ve elde edilen AgNP’ler ortalama 24 nm boyutunda sferik şekillidir. Nanopartiküllerin çeşitli patojenik mikroorganizmalar üzerine antimikrobiyal aktivite çalışmaları, bu nanopartiküllerin Escherichia coli ve Staphylococcus aureus üzerine kuvvetli antibakteriyel ve Candida albicans’a karşı da kuvvetli antifungal etkisi olduğunu göstermiştir. E. coli, S. aureus ve C. albicans için minimum inhibe edici konsantrasyonlar sırasıyla 0.125, 0.125 ve 0.250 g /mL’dir. Sonuçlar, Prunus armeniaca yaprak özütünün etkili antimikrobiyal aktiviteye sahip AgNP’lerin üretiminde kullanılabileceğini ortaya koymuştur.

Anahtar Kelimeler

Antimikrobiyal, Gümüş nanopartikül, Kayısı, Prunus armeniaca yaprak özütü, Yeşil sentez

Destekleyen Kurum

İnönü Üniversitesi Bilimsel Araştırma Projeleri Koordinasyon Birimi

Proje Numarası

2016/111

Teşekkür

Bu çalışma İnönü Üniversitesi Bilimsel Araştırma Projeleri Koordinasyon Birimince Desteklenmiştir. Proje numarası 2016/111.

ANTIMICROBIAL POTENTIAL OF SILVER NANOPARTICLES PRODUCED BY APRICOT LEAF EXTRACT

Öz

Metallic nanoparticles are important substances in medicine. These particles could be prepared by various ways including green synthesis. The production of silver nanoparticles by plant extracts is widely used because of their environmentally friendly properties. In this study, silver nanoparticles have been synthesized by biological method and Apricot tree (Prunus armeniaca) leaf extract was used as reducing agent. The color change and formation of the characteristic absorption peak at 400-500 nm were the first indications of AgNP formation. XRD analysis showed the crystalline particles and obtained AgNPs were generally in spherical shape with the average particle size of 24 nm. Their antimicrobial activity studies against various pathogenic microorganisms showed that they have strong antibacterial activity against Escherichia coli and Staphylococcus aureus and antifungal activity against Candida albicans. The minimum inhibitory concentrations for E. coli, S. aureus and C. albicans were 0.125, 0.125 and 0.250 g/mL, respectively. The results confirmed that Prunus armeniaca leaf extract could be used to produce AgNPs with efficient antimicrobial activity.

Anahtar Kelimeler

Antimicrobial, Apricot, Green Synthesis, Prunus armeniaca leaf extract, Silver nanoparticles

Proje Numarası

2016/111

Kaynakça

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