Effects of Epilepsy on Physical, Cognitive, Visual, Hearing, Speech, Communication and Nutritional Functions in Children with Cerebral Palsy

Yıl 2025, Cilt: 13 Sayı: 1, 204 - 215

Kübra Seyhan Bıyık , Ceren Günbey , Cemil Özal , Merve Tunçdemir , Sefa Üneş , Kıvanç Delioğlu , Mintaze Kerem Günel , Banu Anlar

https://doi.org/10.33715/inonusaglik.1583934

Öz

Epilepsy is a common symptom in children with cerebral palsy (CP). This study aimed to investigate the effects of epilepsy on physical, cognitive, visual, hearing, speech, communication and eating-drinking functions of children with CP. The study consisted of 297 children with CP. Data on epilepsy and functional status were retrospectively scanned through the records based on the Surveillance of Cerebral Palsy in Europe (SCPE) registration system. Physical, speech, communication and eating-drinking functional levels were classified according to the Gross Motor Function Classification System, Manual Ability Classification System, Communication Function Classification System, Viking Speech Scale and Eating-Drinking Ability Classification System. The effects of epilepsy on functions were examined using Chi Square test and Cramer’s V. Epilepsy was associated with ambulation (p<0.001), manual (p<0.001), cognitive (p<0.001), visual (p=0.038), communication (p<0.001) and eating-drinking (p<0.001) functions in children with CP with small to medium effect sizes. While epilepsy is known to strongly affect cognitive functions of children with CP, it can have negative effects on physical, visual, communication and eating-drinking functions. The diagnosis of epilepsy is included in standard registration systems; the use of these systems for national records allows multidisciplinary evaluation in the clinic and can be used reliably for research purposes.

Anahtar Kelimeler

Cerebral palsy, Child, Epilepsy, Function, Registry system

SEREBRAL PALSİLİ ÇOCUKLARDA EPİLEPSİNİN FİZİKSEL, BİLİŞSEL, GÖRME, İŞİTME, KONUŞMA, İLETİŞİM VE BESLENME FONKSİYONLARINA ETKİSİ

Öz

Epilepsi, serebral palsili (SP) çocuklarda yaygın görülen bir semptomdur. Bu çalışmanın amacı epilepsinin SP’li çocukların fiziksel, bilişsel, görme, işitme, konuşma, iletişim ve beslenme fonksiyonlarına etkisini incelemekti. Çalışmaya 297 SP’li çocuk dahil edildi. Avrupa Serebral Palsi Surveyans (SCPE) sistemi değerlendirme formu ile kaydedilen çocukların epilepsi ve fonksiyonel durumları retrospektif olarak tarandı. Fiziksel, iletişim, konuşma ve beslenme fonksiyonları Kaba Motor Fonksiyon Sınıflandırma Sistemi, El Becerileri Sınıflandırma Sistemi, İletişim Fonksiyonları Sınıflandırma Sistemi, Viking Konuşma Ölçeği ve Yeme-içme Becerisi Sınıflandırma Sistemine göre belirlendi. Epilepsinin fonksiyonlar üzerine etkisi Chi Square testi ve Cramer’s V ile incelendi. Epilepsi, SP’li çocuklarda kaba motor (p<0.001), el becerileri (p<0.001), bilişsel (p<0.001), görme (p=0.038), iletişim (p<0.001) ve beslenme (p<0.001) fonksiyonları ile küçük ile orta düzey etki büyüklüğünde ilişkiliydi. Epilepsinin SP’li çocukların işlevleri arasında en fazla bilişsel alana etkileri bilinmekle birlikte fiziksel, görme, iletişim ve beslenmeyi de olumsuz etkilediği görülmüştür. Sonuçların genel olarak literatürdeki çalışmalarla benzerlik göstermesi SCPE standart kayıt sistemindeki verilerin restrospektif araştırmalarda da yararlı ve güvenilir olduklarını, bu sistemde yer alan epilepsinin gerek klinik izlemde, gerekse de araştırmalarda göz önüne alınması gereken bir tanı olduğunu göstermiştir.

Anahtar Kelimeler

Çocuk, Epilepsi, Fonksiyon, Kayıt sistemi, Serebral palsi

Kaynakça

• Akpınar, P., Tezel, C. G., Eliasson, A. C. ve Içağasıoğlu, A. (2010). Reliability and cross-cultural validation of the Turkish version of Manual Ability Classification System (MACS) for children with cerebral palsy. Disability and Rehabilitation, 32(23), 1910-1916. https://doi.org/10.3109/09638281003763796
• Bertoncelli, C. M., Dehan, N., Bertoncelli, D., Bagui, S., Bagui, S. C., Costantini, S.ve Solla, F. (2022). Prediction Model for Identifying Factors Associated with Epilepsy in Children with Cerebral Palsy. Children (Basel), 9(12). https://doi.org/10.3390/children9121918
• Bingöl, H., Kerem-Günel, M. ve Alkan, H. (2023). The Efficacy of Two Models of Intensive Upper Limb Training on Health-Related Quality of Life in Children with Hemiplegic Cerebral Palsy Mainstreamed in Regular Schools: A Double-Blinded, Randomized Controlled Trial. Physiotherapy Theory and Practice, 39(1), 10–25. https://doi.org/10.1080/09593985.2021.1999355
• Bingöl, H. ve Demirtaş-Karaoba, D. (2024). A Comparison of the Functioning and Disability Levels of Children With Hemiplegic and Diplegic Cerebral Palsy Based on ICF-CY Components. Perceptual and Motor Skills, 131(4), 1145–1162. https://doi.org/10.1177/00315125241254130
• Carlsson, M., Olsson, I., Hagberg, G.ve Beckung, E. (2008). Behaviour in children with cerebral palsy with and without epilepsy. Developmental Medicine and Child Neurology, 50(10), 784-789. https://doi.org/10.1111/j.1469-8749.2008.03090.x
• Christine, C., Dolk, H., Platt, M. J., Colver, A., Prasauskiene, A. ve Krägeloh-Mann, I. (2007). Recommendations from the SCPE collaborative group for defining and classifying cerebral palsy. Developmental Medicine and Child Neurology Supplement, 109, 35-38. https://doi.org/10.1111/j.1469-8749.2007.tb12626.x
• El, O., Baydar, M., Berk, H., Peker, O., Koşay, C. ve Demiral, Y. (2012). Interobserver reliability of the Turkish version of the expanded and revised gross motor function classification system. Disability and Rehabilitation, 34(12), 1030-1033. https://doi.org/10.3109/09638288.2011.632466
• Günel, M. K., Özal, C., Seyhan, K., Arslan, S. S., Demir, N. ve Karaduman, A. (2020). Yeme ve İçme Becerileri Siniflandirma Sisteminin Türkçe Versiyonu: serebral Palsili Çocuklarda Değerlendirici-İçi Güvenirliği ve Diğer Fonksiyonel Siniflandirma Sistemleri İle İlişkisi. Türk Fizyoterapi ve Rehabilitasyon Dergisi, 31(3), 218-224.
• Kılıç, M. A., Yildiz, E. P., Kurekci, F., Coskun, O., Cura, M., Avci, R. ve Genc, H. M. (2024). Association of epilepsy with neuroimaging patterns in children with cerebral palsy. Acta Neurologica Belgica, 124(2), 567-572. https://doi.org/10.1007/s13760-023-02385-w
• Kim, H. Y. (2017). Statistical notes for clinical researchers: Chi-squared test and Fisher's exact test. Restorative Dentistry and Endodontics, 42(2), 152-155. https://doi.org/10.5395/rde.2017.42.2.152
• Mutlu, A., Kara Ö, K., Livanelioğlu, A., Karahan, S., Alkan, H., Yardımcı, B. N.ve Hidecker, M. J. C. (2018). Agreement between parents and clinicians on the communication function levels and relationship of classification systems of children with cerebral palsy. Disability and Health Journal, 11(2), 281-286. https://doi.org/10.1016/j.dhjo.2017.11.001
• Novak, I. (2014). Evidence-based diagnosis, health care, and rehabilitation for children with cerebral palsy. Journal of Child Neurology, 29(8), 1141-1156. https://doi.org/10.1177/0883073814535503
• Novak, I., Hines, M., Goldsmith, S.ve Barclay, R. (2012). Clinical prognostic messages from a systematic review on cerebral palsy. Pediatrics, 130(5), e1285-1312. https://doi.org/10.1542/peds.2012-0924
• Rosenbaum, P., Paneth, N., Leviton, A., Goldstein, M., Bax, M., Damiano, D., . . . Jacobsson, B. (2007). A report: the definition and classification of cerebral palsy April 2006. Developmental Medicine and Child Neurology Supplement, 109, 8-14.
• Sellers, D., Mandy, A., Pennington, L., Hankins, M. ve Morris, C. (2014). Development and reliability of a system to classify the eating and drinking ability of people with cerebral palsy. Developmental Medicine and Child Neurology, 56(3), 245-251.
• Sellier, E., Uldall, P., Calado, E., Sigurdardottir, S., Torrioli, M. G., Platt, M. J. ve Cans, C. (2012). Epilepsy and cerebral palsy: characteristics and trends in children born in 1976-1998. European Journal Paediatric Neurology, 16(1), 48-55. https://doi.org/10.1016/j.ejpn.2011.10.003
• Seyhan-Bıyık, K., Esen-Aydınlı, I. F., Sel, S. A., İncebay, Ö., Özcebe, E., Kerem-Günel, M., . . . Pennington, L. (2023). Psychometric properties of the Viking Speech Scale-Turkish version for children with cerebral palsy aged 4-18 years based on live and video-based observation. International Journal of Language and Communication Disorders, 58(3), 687-703. https://doi.org/10.1111/1460-6984.12810
• Singhi, P., Jagirdar, S., Khandelwal, N. ve Malhi, P. (2003). Epilepsy in children with cerebral palsy. Journal of Child Neurology, 18(3), 174-179. https://doi.org/10.1177/08830738030180030601
• Szpindel, A., Myers, K. A., Ng, P., Dorais, M., Koclas, L., Pigeon, N., . . . Oskoui, M. (2022). Epilepsy in children with cerebral palsy: a data linkage study. Developmental Medicine and Child Neurology, 64(2), 259-265. https://doi.org/10.1111/dmcn.15028
• Ünes, S., Tunçdemir, M., Özal, C., Çankaya, O., Seyhan Bıyık, K., Delioğlu, K., . . . Anlar, B. (2022). Relationship among four functional classification systems and parent interpredicted intelligence level in children with different clinical types of cerebral palsy. Developmental Neurorehabilitation, 25(6), 410-416. https://doi.org/10.1080/17518423.2022.2051629