GENETIC SYNDROMES AS A CAUSE OF TREATMENT RESISTANCE IN SCHIZOPHRENIA: A CASE WITH TRIPLE X SYNDROME

Bahadır Turan; Mehmet Akif Akıncı; İbrahim Selçuk Esin; Onur Burak Dursun

doi:10.26650/IUITFD.2019.0011

Olgu Sunumu

GENETIC SYNDROMES AS A CAUSE OF TREATMENT RESISTANCE IN SCHIZOPHRENIA: A CASE WITH TRIPLE X SYNDROME

Yıl 2019, , 162 - 163, 16.07.2019

Bahadır Turan Mehmet Akif Akıncı İbrahim Selçuk Esin , Onur Burak Dursun

https://doi.org/10.26650/IUITFD.2019.0011

Öz

Triple X syndrome (47, XXX) is a numerical chromosomal alteration that affects 1/1.000 females, in which the individual is born with an extra X chromosome. Trisomy X is a relatively common but under- recognized chromosomal disorder associated with characteristic cognitive and behavioural features of varying severity. We report a 16-year old patient with Triple X syndrome and resistant schizophrenia. It is remarkable that genetic syndromes may be associated with resistance to treatment of psychiatric problems. Therefore in cases with treatment resistance, the genetic analysis should absolutely be examined.

Anahtar Kelimeler

Schizophrenia, treatment resistance, Triple X syndrome

Kaynakça

1. Afshan A. Triple X syndrome. J Pak Med Assoc 2012;62(4):392.
2. Woodhouse WJ, Holland AJ, McLean G, Reveley AM. The association between triple X and psychosis. Br J Psychiatry. 1992;160(4):554-7.
3. Otter M, Schrander-Stumpel CT, Curfs LM. Triple X syndrome: a review of the literature. Eur J Hum Genet. 2010;18(3):265.
4. Lenroot RK, Blumenthal JD, Wallace GL, Clasen LS, Lee NR, Giedd JN. A case-control study of brain structure and behavioral characteristics in 47, XXX syndrome. Genes Brain Behav. 2014;13(8):841-9.

ŞİZOFRENİDE TEDAVİYE DİRENÇ NEDENİ OLARAK GENETİK SENDROMLAR: TRİPLE X SENDROMLU BİR OLGU

Yıl 2019, , 162 - 163, 16.07.2019

Bahadır Turan Mehmet Akif Akıncı İbrahim Selçuk Esin , Onur Burak Dursun

https://doi.org/10.26650/IUITFD.2019.0011

Öz

Amaç: Triple X sendromu (47, XXX), kadınlarda ekstra bir X kromozomunun varlığı ile karakterize, 1/1.000 kişide bir görülen bir sendromdur. Trizomi X, değişken şiddette bilişsel ve davranışsal özelliklerle karakterize bir kromozomal hastalıktır. Bu olgu sunumunda; Triple X sendromlu ve dirençli şizofreni tanısı alan 16 yaşında bir vaka sunuyoruz. Genetik sendromların psikiyatrik problemlerin tedavisinde tedaviye dirençle ilişkili olabileceği ve bu nedenle tedaviye dirençli olgularda genetik analizlerin mutlaka yapılması gerektiği göz önünde bulundurulmalıdır.

Anahtar Kelimeler

Şizofreni, tedaviye direnç, Triple X sendrom

Kaynakça

1. Afshan A. Triple X syndrome. J Pak Med Assoc 2012;62(4):392.
2. Woodhouse WJ, Holland AJ, McLean G, Reveley AM. The association between triple X and psychosis. Br J Psychiatry. 1992;160(4):554-7.
3. Otter M, Schrander-Stumpel CT, Curfs LM. Triple X syndrome: a review of the literature. Eur J Hum Genet. 2010;18(3):265.
4. Lenroot RK, Blumenthal JD, Wallace GL, Clasen LS, Lee NR, Giedd JN. A case-control study of brain structure and behavioral characteristics in 47, XXX syndrome. Genes Brain Behav. 2014;13(8):841-9.

Toplam 4 adet kaynakça vardır.

Ayrıntılar

Birincil Dil	İngilizce
Konular	Sağlık Kurumları Yönetimi
Bölüm	Olgu Sunumu
Yazarlar	Bahadır Turan Bu kişi benim 0000-0003-1190-9589 Mehmet Akif Akıncı Bu kişi benim 0000-0002-6436-4394 İbrahim Selçuk Esin 0000-0001-5598-2097 Onur Burak Dursun Bu kişi benim 0000-0003-2990-9851
Yayımlanma Tarihi	16 Temmuz 2019
Gönderilme Tarihi	18 Ekim 2018
Yayımlandığı Sayı	Yıl 2019

Kaynak Göster

APA	Turan, B., Akıncı, M. A., Esin, İ. S., Dursun, O. B. (2019). GENETIC SYNDROMES AS A CAUSE OF TREATMENT RESISTANCE IN SCHIZOPHRENIA: A CASE WITH TRIPLE X SYNDROME. Journal of Istanbul Faculty of Medicine, 82(3), 162-163. https://doi.org/10.26650/IUITFD.2019.0011
AMA	Turan B, Akıncı MA, Esin İS, Dursun OB. GENETIC SYNDROMES AS A CAUSE OF TREATMENT RESISTANCE IN SCHIZOPHRENIA: A CASE WITH TRIPLE X SYNDROME. İst Tıp Fak Derg. Temmuz 2019;82(3):162-163. doi:10.26650/IUITFD.2019.0011
Chicago	Turan, Bahadır, Mehmet Akif Akıncı, İbrahim Selçuk Esin, ve Onur Burak Dursun. “GENETIC SYNDROMES AS A CAUSE OF TREATMENT RESISTANCE IN SCHIZOPHRENIA: A CASE WITH TRIPLE X SYNDROME”. Journal of Istanbul Faculty of Medicine 82, sy. 3 (Temmuz 2019): 162-63. https://doi.org/10.26650/IUITFD.2019.0011.
EndNote	Turan B, Akıncı MA, Esin İS, Dursun OB (01 Temmuz 2019) GENETIC SYNDROMES AS A CAUSE OF TREATMENT RESISTANCE IN SCHIZOPHRENIA: A CASE WITH TRIPLE X SYNDROME. Journal of Istanbul Faculty of Medicine 82 3 162–163.
IEEE	B. Turan, M. A. Akıncı, İ. S. Esin, ve O. B. Dursun, “GENETIC SYNDROMES AS A CAUSE OF TREATMENT RESISTANCE IN SCHIZOPHRENIA: A CASE WITH TRIPLE X SYNDROME”, İst Tıp Fak Derg, c. 82, sy. 3, ss. 162–163, 2019, doi: 10.26650/IUITFD.2019.0011.
ISNAD	Turan, Bahadır vd. “GENETIC SYNDROMES AS A CAUSE OF TREATMENT RESISTANCE IN SCHIZOPHRENIA: A CASE WITH TRIPLE X SYNDROME”. Journal of Istanbul Faculty of Medicine 82/3 (Temmuz 2019), 162-163. https://doi.org/10.26650/IUITFD.2019.0011.
JAMA	Turan B, Akıncı MA, Esin İS, Dursun OB. GENETIC SYNDROMES AS A CAUSE OF TREATMENT RESISTANCE IN SCHIZOPHRENIA: A CASE WITH TRIPLE X SYNDROME. İst Tıp Fak Derg. 2019;82:162–163.
MLA	Turan, Bahadır vd. “GENETIC SYNDROMES AS A CAUSE OF TREATMENT RESISTANCE IN SCHIZOPHRENIA: A CASE WITH TRIPLE X SYNDROME”. Journal of Istanbul Faculty of Medicine, c. 82, sy. 3, 2019, ss. 162-3, doi:10.26650/IUITFD.2019.0011.
Vancouver	Turan B, Akıncı MA, Esin İS, Dursun OB. GENETIC SYNDROMES AS A CAUSE OF TREATMENT RESISTANCE IN SCHIZOPHRENIA: A CASE WITH TRIPLE X SYNDROME. İst Tıp Fak Derg. 2019;82(3):162-3.