THE ROLE OF ROUTINE LABORATORY TESTING IN THE MANAGEMENT OF CHRONIC URTICARIA

Öz

Objective: The diagnosis of chronic spontaneous urticaria (CSU) is mainly based on a thorough patient history and physical examination. Although limited laboratory tests are recommended, detailed screening laboratory tests are frequently required by specialists to exclude underlying diseases or to identify causative factors. The aim of this study was to evaluate laboratory findings of patients with CSU and its impact on the diagnosis and management of the disease. Material and Method: The demographic and clinical findings, laboratory tests, and treatment regimens of patients diagnosed as CSU were evaluated. Results: A total of 113 (61 M, 52 F) cases with CSU were evaluated. The median age of the patients was seven years (IQR: 7-10). Among 911 ordered tests, only 156 (17.1%) were found abnormal. The most common abnormalities were detected in the complete blood count tests. Eighty-three (73.4%) of 156 patients, were receiving the first step treatment. Laboratory test results did not affect or cause any alterations in the treatment regimen of the patients. Conclusion: Although detailed laboratory tests did not change the course of urticaria in patients with CSU, laboratory tests can be planned considering the personal characteristics of each patient.

Anahtar Kelimeler

• Chronic spontaneous urticaria
• autoantibody
• blood test

KRONİK ÜRTİKER YÖNETİMİNDE RUTİN LABORATUVAR TESTLERİNİN YERİ

Öz

Amaç: Kronik spontan ürtiker (KSÜ) tanısı, esas olarak detaylı alınmış bir öykü ve fizik muayene ile konulur. Tanı için sınırlı sayıda laboratuvar testlerinin yapılması önerilir. Ancak altta yatan hastalıkları dışlamak ve/veya neden olan faktörleri belirlemek amacı ile uzmanlar tarafından sıklıkla laboratuvar testleri önerilenden daha fazla istenmektedir. Çalışmamızda KSÜ tanılı hastalarda laboratuvar bulgularının hastalığın tanısı ve yönetimi üzerine olan etkisini değerlendirmeyi amaçladık. Gereç ve Yöntem: Kronik spontan ürtiker tanısı konulan hastaların demografik ve klinik bulguları, laboratuvar test sonuçları ve tedavileri değerlendirildi. Bulgular: Kronik spontan ürtikerli toplam 113 hasta (61 E, 52 K) değerlendirildi. Medyan yaş 7 yıl, (çeyrekler arası açıklığı; IQR 7-10) idi. Toplam 911 testten sadece 156’sı (%17,1) anormal idi. En sık anormallik tam kan sayımında saptandı. Hastaların 83’ü (%73,4) birinci basamak tedavi almakta idi. Laboratuvar test sonuçları hiçbir hastanın tedavisini etkilemedi ve tedavi protokollerinde bir değişiklik yapılmasına neden olmadı. Sonuç: Detaylı olarak yapılan laboratuvar testleri KSÜ’li hastalarda ürtikerin seyrini değiştirmese de laboratuvar tetkikleri her hastanın kişisel özellikleri göz önüne alınarak planlanabilir.

Anahtar Kelimeler

• Kronik spontan ürtiker
• otoantikor
• kan testleri

Kaynakça

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