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İKİ VAKA NEDENİYLE TROMBOTİK TROMBOSİTOPENİK PURPURA

Yıl 2008, Cilt: 71 Sayı: 4, 124 - 126, 14.11.2011

Uğur Ersoy M. Fatih Akdoğan Fatih Palit Haluk Şavlı Hasan Mağın Murat Gücün At All.

Öz

Trombotik Trombositopenik Purpura (TTP) ; Ateş, akut böbrek yetmezliği, nörolojik bozukluklar, trombositopeni ve mikroanjiopatik hemolitik anemi ile seyreden bir sendromdur. Nadir görülen bu hastalık (4-11/1.000.000), klinik olarak dissemine intravasküler koagulasyon (DİK), hemolitik üremik sendrom (HÜS) ve Evans sendromu gibi anemi yapan diğer nedenlerle karışabilir. İki vaka nedeniyle, TTP güncel literatür ışığında tekrar gözden geçirilmiştir.

Anahtar Kelimeler

Trombositopeni Purpura Plazmaferez

Kaynakça

  • Allford SL,Hunt BJ, Rose P, Machine S. Guidelines on the diag- nosis and management of the thrombotic microangiopathic ha- emolytic anaemias. Br J Haematol 2003;120:556-573.
  • Carmichae DS , Medley DRK .Heparin in thrombotic microan- giopathy Lancet 1966;1:1421-1424.
  • Current concepts in thrombotic thrombocytopenic purpura. Annu Rev Med 2006; 57: 419-436).
  • Del Zoppo, G.J.: Antiplatelet theraphy in thrombotic throm- bocytopenic purpura. Semin Hematology 1987; 24:32.
  • Elliot MA, Nichols, WL.Thorombotic trombositopenic purpura and hemolitic uremic syndrome.Mayo Clin Proc 2001;76:1154- 1162.
  • Feldman JD , Mardiney MR ,Unanue ER ,Cutting H .The vascu- lar pathology of thrombotic thrombocytopenic purpura .An im- munohistochemical and ultra structural study. Lab Invest 1966;15:927-946.
  • GA Rock. KH Shumak. NA Buskard.VS Blanchette.JG Kel- ton.RC Nair and RA Spasoff comparison of plasma exchange with plasma infusion in the treatment of thrombotic thrombocy- topenic purpura canadian Apheresis study group N Eng J Med 1991;325:393-397.
  • James N.George How I treat patients with thrombotic throm- bocytopenic purpura- hmolytic uremic syndrome. Blood 2000 ;96:1223-1229.
  • George JN,Gilcher RO,Smith JW , Chandler L, Duvall D.Thrombotic Thrombocytopenic Purpura – Hemolytic Uremic Syndrome : diagnosis nand manangement .J Clin Apheresis 1998;13:120-125.
  • Havens ,P.L.,O’Rouke P.P.,Hahn,J.,Higgins,J., Walker,A.M.:La- boratory and clinical varables to predict outcome in hemolytic- üremic syndrome AJDC 1988;142:961.
  • James N. George, Thorombotic trombositopenic purpura N Engl J Med 2006;354:1927-3195.
  • Kennedy SS, Zacharsky LR,Beck JR.Thrombotic thrombosito- penic purpura :analysis of 48 unselected cases. Semin Thromb Hemost 1980;6:341-349.
  • Kutell MA ,Alfrey CP ,Hetting RA.TTP treatment N Engl J Med 1971;285:971-972.
  • Melnyk, A.M.S.,Solez K., Kjellstrand, C.M.:Hemolytic uremic syndrome in adults. Arch Intern Med 1995;155:2077.
  • Miller,J.M., Pastorek ,JG.:Thrombotic thrombocytopenic purpu- ra and hemolytic üremic syndrome in pregnancy.Clin Obstet Gynecol 1991;34:41.
  • Neame PB.Immunologic and other factors in thrombotic throm- bocytopenic purpura (TTP). semin Thromb Hemost 1980;6:416- 429.
  • Ponticelli,C.,Rivolta ,E.,Imbasciati ,E., Rossi,E., Mannuc- ci,P.M.:Hemolytic üremic syndrome. Arch Intern Med 1980; 140:335.
  • Rock ,G.A.,Shumak,K.H.,Buskard ,N.A.: Comparision of plasma Exchange with plasma infusion the treatment of TTP N Eng J Med 1991;325:326.
  • Rock G ,Porta C , Bobbio-Pallavicini E.Thrombotic thrombocy- topenic purpura treatment in year 2000.Haematologica 2000; 85:410-419.
  • Sadler JE,Moake JL. Recent advances in thrombotic trombocyto- penic purpura American Society of Hematology, 2004; 407-423.
  • Terrell DR, Williams LA, Vesely SK,Lammle B, Hovinga JA, George JN,The incidence of thrombotic thrombocytopenic pur- pura-hemolytic uremic syndrome: all patients, idiopathic patients, and patients with severe ADAMTS-13 deficiency. J Thromb Ha- emost 2005; 3:1432-1436.
  • Weinstein ,L.: Syndrome of hemolysis, elevated liver enzymes and low platelet count : A severe consequence of hypertension in pregnancy. Am J Obstet Gynecol 1982; 142:159.

Yıl 2008, Cilt: 71 Sayı: 4, 124 - 126, 14.11.2011

Uğur Ersoy M. Fatih Akdoğan Fatih Palit Haluk Şavlı Hasan Mağın Murat Gücün At All.

Öz

Kaynakça

  • Allford SL,Hunt BJ, Rose P, Machine S. Guidelines on the diag- nosis and management of the thrombotic microangiopathic ha- emolytic anaemias. Br J Haematol 2003;120:556-573.
  • Carmichae DS , Medley DRK .Heparin in thrombotic microan- giopathy Lancet 1966;1:1421-1424.
  • Current concepts in thrombotic thrombocytopenic purpura. Annu Rev Med 2006; 57: 419-436).
  • Del Zoppo, G.J.: Antiplatelet theraphy in thrombotic throm- bocytopenic purpura. Semin Hematology 1987; 24:32.
  • Elliot MA, Nichols, WL.Thorombotic trombositopenic purpura and hemolitic uremic syndrome.Mayo Clin Proc 2001;76:1154- 1162.
  • Feldman JD , Mardiney MR ,Unanue ER ,Cutting H .The vascu- lar pathology of thrombotic thrombocytopenic purpura .An im- munohistochemical and ultra structural study. Lab Invest 1966;15:927-946.
  • GA Rock. KH Shumak. NA Buskard.VS Blanchette.JG Kel- ton.RC Nair and RA Spasoff comparison of plasma exchange with plasma infusion in the treatment of thrombotic thrombocy- topenic purpura canadian Apheresis study group N Eng J Med 1991;325:393-397.
  • James N.George How I treat patients with thrombotic throm- bocytopenic purpura- hmolytic uremic syndrome. Blood 2000 ;96:1223-1229.
  • George JN,Gilcher RO,Smith JW , Chandler L, Duvall D.Thrombotic Thrombocytopenic Purpura – Hemolytic Uremic Syndrome : diagnosis nand manangement .J Clin Apheresis 1998;13:120-125.
  • Havens ,P.L.,O’Rouke P.P.,Hahn,J.,Higgins,J., Walker,A.M.:La- boratory and clinical varables to predict outcome in hemolytic- üremic syndrome AJDC 1988;142:961.
  • James N. George, Thorombotic trombositopenic purpura N Engl J Med 2006;354:1927-3195.
  • Kennedy SS, Zacharsky LR,Beck JR.Thrombotic thrombosito- penic purpura :analysis of 48 unselected cases. Semin Thromb Hemost 1980;6:341-349.
  • Kutell MA ,Alfrey CP ,Hetting RA.TTP treatment N Engl J Med 1971;285:971-972.
  • Melnyk, A.M.S.,Solez K., Kjellstrand, C.M.:Hemolytic uremic syndrome in adults. Arch Intern Med 1995;155:2077.
  • Miller,J.M., Pastorek ,JG.:Thrombotic thrombocytopenic purpu- ra and hemolytic üremic syndrome in pregnancy.Clin Obstet Gynecol 1991;34:41.
  • Neame PB.Immunologic and other factors in thrombotic throm- bocytopenic purpura (TTP). semin Thromb Hemost 1980;6:416- 429.
  • Ponticelli,C.,Rivolta ,E.,Imbasciati ,E., Rossi,E., Mannuc- ci,P.M.:Hemolytic üremic syndrome. Arch Intern Med 1980; 140:335.
  • Rock ,G.A.,Shumak,K.H.,Buskard ,N.A.: Comparision of plasma Exchange with plasma infusion the treatment of TTP N Eng J Med 1991;325:326.
  • Rock G ,Porta C , Bobbio-Pallavicini E.Thrombotic thrombocy- topenic purpura treatment in year 2000.Haematologica 2000; 85:410-419.
  • Sadler JE,Moake JL. Recent advances in thrombotic trombocyto- penic purpura American Society of Hematology, 2004; 407-423.
  • Terrell DR, Williams LA, Vesely SK,Lammle B, Hovinga JA, George JN,The incidence of thrombotic thrombocytopenic pur- pura-hemolytic uremic syndrome: all patients, idiopathic patients, and patients with severe ADAMTS-13 deficiency. J Thromb Ha- emost 2005; 3:1432-1436.
  • Weinstein ,L.: Syndrome of hemolysis, elevated liver enzymes and low platelet count : A severe consequence of hypertension in pregnancy. Am J Obstet Gynecol 1982; 142:159.
Toplam 22 adet kaynakça vardır.

Ayrıntılar

Birincil Dil Türkçe
Bölüm Olgu Sunumu
Yazarlar

Uğur Ersoy Bu kişi benim

M. Fatih Akdoğan Bu kişi benim

Fatih Palit Bu kişi benim

Haluk Şavlı Bu kişi benim

Hasan Mağın Bu kişi benim

Murat Gücün Bu kişi benim

At All. Bu kişi benim

Yayımlanma Tarihi 14 Kasım 2011
Gönderilme Tarihi 14 Kasım 2011
Yayımlandığı Sayı Yıl 2008 Cilt: 71 Sayı: 4

Kaynak Göster

APA Ersoy, U., Akdoğan, M. F., Palit, F., Şavlı, H., vd. (2011). İKİ VAKA NEDENİYLE TROMBOTİK TROMBOSİTOPENİK PURPURA. Journal of Istanbul Faculty of Medicine, 71(4), 124-126.
AMA Ersoy U, Akdoğan MF, Palit F, Şavlı H, Mağın H, Gücün M, All. A. İKİ VAKA NEDENİYLE TROMBOTİK TROMBOSİTOPENİK PURPURA. İst Tıp Fak Derg. Kasım 2011;71(4):124-126.
Chicago Ersoy, Uğur, M. Fatih Akdoğan, Fatih Palit, Haluk Şavlı, Hasan Mağın, Murat Gücün, ve At All. “İKİ VAKA NEDENİYLE TROMBOTİK TROMBOSİTOPENİK PURPURA”. Journal of Istanbul Faculty of Medicine 71, sy. 4 (Kasım 2011): 124-26.
EndNote Ersoy U, Akdoğan MF, Palit F, Şavlı H, Mağın H, Gücün M, All. A (01 Kasım 2011) İKİ VAKA NEDENİYLE TROMBOTİK TROMBOSİTOPENİK PURPURA. Journal of Istanbul Faculty of Medicine 71 4 124–126.
IEEE U. Ersoy, M. F. Akdoğan, F. Palit, H. Şavlı, H. Mağın, M. Gücün, ve A. All., “İKİ VAKA NEDENİYLE TROMBOTİK TROMBOSİTOPENİK PURPURA”, İst Tıp Fak Derg, c. 71, sy. 4, ss. 124–126, 2011.
ISNAD Ersoy, Uğur vd. “İKİ VAKA NEDENİYLE TROMBOTİK TROMBOSİTOPENİK PURPURA”. Journal of Istanbul Faculty of Medicine 71/4 (Kasım 2011), 124-126.
JAMA Ersoy U, Akdoğan MF, Palit F, Şavlı H, Mağın H, Gücün M, All. A. İKİ VAKA NEDENİYLE TROMBOTİK TROMBOSİTOPENİK PURPURA. İst Tıp Fak Derg. 2011;71:124–126.
MLA Ersoy, Uğur vd. “İKİ VAKA NEDENİYLE TROMBOTİK TROMBOSİTOPENİK PURPURA”. Journal of Istanbul Faculty of Medicine, c. 71, sy. 4, 2011, ss. 124-6.
Vancouver Ersoy U, Akdoğan MF, Palit F, Şavlı H, Mağın H, Gücün M, All. A. İKİ VAKA NEDENİYLE TROMBOTİK TROMBOSİTOPENİK PURPURA. İst Tıp Fak Derg. 2011;71(4):124-6.

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