The Effect Of Dietary Supplements On Weight Regulation

Öz

Being obese and overweight has become metabolic disorders that effects approximately one third of the population in the world. The most effective solution for obesity treatment is to create a lifestyle change with a balanced diet. However, the lifestyle change, which should be sustained in the long term, fails for most obese individuals due to difficulty in adaptation. Difficulties in achieving weight loss, lead these people to nutritional supplements, which are gaining in popularity. Plant products are used by the majority of population for better health. In parallel with this, the use of nutritional supplements has increased by obese and overweight people for support weight loss. Bioactive compounds in the dietary supplements which are consumed by obese and overweight individuals for weight loss, can affect weight regulation by various metabolic means such as inhibiting enzymes in the digestive system, increasing lipid metabolism, suppressing appetite. Although it has been reported that some dietary supplements provide weight control through different metabolic pathways, it should not be considered that there may be side effects that threaten human health. Therefore, it is important to evaluate the scientific data to make recommendations for safety use. In this review, the effect mechanism of some dietary supplements and weight loss medications in preventing obesity was investigated, and it was aimed to present a new perspective on obesity prevention and treatment strategies.

Besin Destekleri ve İlaçların Ağırlık Regülasyonuna Etkisi

Öz

Obez ve fazla vücut ağırlığına sahip olma durumu, dünyada yaklaşık olarak her üç kişiden birinde var olan metabolik bozukluklardan biri haline gelmiştir. Obezite tedavisi için en etkili çözüm, dengeli bir beslenme planı ile birlikte yaşam tarzı değişikliğinin oluşturulmasıdır. Ancak uzun vadede sürdürülmesi gereken bu yaşam tarzı değişikliği, obez bireylerin çoğu için uyum zorluğu nedeniyle başarısız sonuçlanmaktadır. Ağırlık kaybını sağlamadaki zorluklar bu kişileri, popülerliği artan besin desteklerine yöneltmektedir. Birçok bitkiden elde edilen ürünler, dünya nüfusunun çoğunluğu tarafından sağlığın iyileştirilmesi ve geliştirilmesi için kullanılmaktadır. Buna paralel olarak, obez ve fazla vücut ağırlığına sahip kişiler tarafından ağırlık kaybını destekleyeceği düşünülerek, besin desteklerinin kullanımı artış göstermiştir. Tüketilen besin desteklerinin içeriğindeki biyoaktif bileşikler; sindirim sisteminde görev alan enzimleri inhibe etme, lipit metabolizmasını arttırma, iştahı baskılama gibi çeşitli metabolik yollarla ağırlık regülasyonuna etki edebildiği varsayılarak fazla vücut ağırlığına sahip bireyler tarafından kullanılmaktadır. Bazı besin bileşenlerinin farklı metabolik yolaklarla ağırlık kontrolünü sağladığı bildirilmekle beraber, bunun aksi yönde insan sağlığını tehdit eden yan etkilerinin de olabileceği unutulmamalıdır. Bu nedenle, mevcut bilimsel veriler ve güvenli kullanım tavsiyelerinin dikkatlice araştırılması önem arz etmektedir. Bu derlemede, bazı besin desteklerinin ve ilaçların obeziteyi önlemedeki etki mekanizması araştırılmış, obeziteyi önleme ve tedavi etme stratejilerine bakış açısı sunmak amaçlanmıştır.

Anahtar Kelimeler

• Ağırlık Regülasyonu
• Besin takviyeleri
• Bitkisel Destekler
• Obezite

Kaynakça

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