Oreochromis niloticus'un Karaciğerinde Fungisit Propiconazole'un Oksidatif Stres Parametreleri ve Antioksidan Sistem Enzimleri Üzerine Etkileri

Ozge Temiz

doi:10.35229/jaes.532079

TR EN

Oreochromis niloticus'un Karaciğerinde Fungisit Propiconazole'un Oksidatif Stres Parametreleri ve Antioksidan Sistem Enzimleri Üzerine Etkileri

Öz

Bu Araştırmada, fungisit propiconazole’un 0.5 ppb ve 2.5 ppb derişim etkilerinde 7 gün ve 28 gün sürelerde Oreochromis niloticus’un karaciğer dokusunda, süperoksit dismutaz (SOD), katalaz (CAT), glutatyon peroksidaz (GPx) ve glutatyon S transferaz (GST) antioksidan sistem enzim aktiviteleri ve oksidatif stres parametreleri glutatyon (GSH) ve tiyobarbitürik asit reaktif maddeleri (TBARS) miktarlarındaki değişimler spektrofotometrik yöntemlerle belirlenmiştir.

Çalışmamızda karaciğer dokusunda GSH miktarı ve GSH-bağımlı GPx ve GST aktivitesi 7. günde artarken; 28. günde GSH miktarında azalma ve GST aktivitelerinde artış belirlenmiştir. SOD ve CAT aktiviteleri 7. günde artarken 28. günde azalmıştır. TBARS düzeylerinde propiconazole etkisinde süreye ve derişime bağlı olarak artış göstermektedir.

Çalışma sonuçlarına göre propiconazole etkisinde O. niloticus’da antioksidan sistem enzim aktivitelerinde ve oksidatif stres parametrelerindeki değişimler propiconazole’un hepatotoksik etkiye neden olduğu belirlenmiştir.

Anahtar Kelimeler

Fungisit,Propiconazole,Oreochromis niloticus,Karaciğer,Antioksidan sistem,Glutatyon

Kaynakça

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Ayrıntılar

Birincil Dil

Türkçe

Konular

-

Bölüm

Araştırma Makalesi

Yazarlar

Ozge Temiz ^*
0000-0003-0668-5744
Türkiye

Yayımlanma Tarihi

30 Nisan 2019

Gönderilme Tarihi

25 Şubat 2019

Kabul Tarihi

23 Mart 2019

Yayımlandığı Sayı

Yıl 2019 Cilt: 4 Sayı: 1

DOI

https://doi.org/10.35229/jaes.532079

IZ

https://izlik.org/JA38CE88PE

APA

Temiz, O. (2019). Oreochromis niloticus’un Karaciğerinde Fungisit Propiconazole’un Oksidatif Stres Parametreleri ve Antioksidan Sistem Enzimleri Üzerine Etkileri. Journal of Anatolian Environmental and Animal Sciences, 4(1), 43-47. https://doi.org/10.35229/jaes.532079