Contralateral Hyperhidrosis After Hemorrhagic Cerebrovascular Disease: A Case Report

Öz

Hyperhidrosis is the excessive sweating caused by overactive sweat glands. It impacts individuals’ quality of life, leading to skin infections, social anxiety disorders, and challenges in caring for patients. Hyperhidrosis can be primary or secondary, with secondary cases linked to cerebrovascular diseases (CVD). This case study describes a 70-year-old male patient with hemorrhagic CVD and hyperhidrosis. His hyperhidrosis, which began 18 months after the CVD diagnosis, showed improvement with gabapentin treatment.

Anahtar Kelimeler

• hemorrhage
• hyperhidrosis
• stroke

Hemorajik Serebrovasküler Hastalık Sonrası Kontralateral Hiperhidrozis: Vaka Sunumu

Öz

Hiperhidroz, aşırı aktif ter bezlerinin neden olduğu aşırı terlemedir. Bireylerin yaşam kalitesini etkileyerek cilt enfeksiyonları- na, sosyal anksiyete bozukluklarına ve hastaların bakımında zorluklara yol açar. Hiperhidroz, birincil veya ikincil olabilir ve ikincil vakalar serebrovasküler hastalıklarla (SVD) bağlantılıdır. Bu vaka çalışması, hemorajik SVD ve hiperhidrozu olan 70 yaşında bir erkek hastayı tanımlamaktadır. SVD tanısından 18 ay sonra başlayan hiperhidrozu, gabapentin tedavisiyle düzelme gösterdi.

Anahtar Kelimeler

• hemoraji
• hiperhidroz
• inme

Kaynakça

1. 1. Önder M, Aksoy G. Hiperhidroz/Hyperhidrosis. Turkderm: Turk Arch Dermatol Venereol. 2011;45(1):2.
2. 2. Faruqi S, Redmond G, Ram P, Owens VB, Sangster G, Barrett JA. Hemihyperhidrosis in cerebral infarction. Age Ageing. 2004;33(5):514-515.
3. 3. Ohn MH, Ohn KM, Yin KN, Guang TY, Luen NP, Bing CL. Unilateral Hemihyperhidrosis in a stroke patient and literature review on its clinicoanatomical correlation. Borneo J Med Sci. 2020;14(2):41.
4. 4. Baguley IJ, Perkes IE, Fernandez-Ortega J-F, Rabinstein AA, Dolce G, Hendricks HT, et al. Paroxysmal sympathetic hyperactivity after acquired brain injury: consensus on conceptual definition, nomenclature, and diagnostic criteria. J Neurotrauma. 2014;31(17):1515-1520.
5. 5. Li Z, Chen W, Zhu Y, Han K, Wang J, Chen J, et al. Risk factors and clinical features of paroxysmal sympathetic hyperactivity after spontaneous intracerebral hemorrhage. Auton Neurosci. 2020;225:102643.
6. 6. Korpelainen JT, Sotaniemi KA, Myllylä VV. Hyperhidrosis as a reflection of autonomic failure in patients with acute hemispheral brain infarction. An evaporimetric study. Stroke. 1992;23(9):1271- 1275.
7. 7. Labar DR, Mohr JP, Nichols FT 3rd, Tatemichi TK. Unilateral hyperhidrosis after cerebral infarction. Neurology. 1988;38(11):1679-1682.
8. 8. Naghdi S, Ansari NN, Mansouri K, Hasson S. A neurophysiological and clinical study of Brunnstrom recovery stages in the upper limb following stroke. Brain Inj. 2010;24(11):1372-1378.

9. 9. McConaghy JR, Fosselman D. Hyperhidrosis: Management options. Am Fam Physician. 2018;97(11):729-734.
10. 10. Cordonnier C, Demchuk A, Ziai W, Anderson CS. Intracerebral haemorrhage: current approaches to acute management. Lancet. 2018;392(10154):1257-1268.
11. 11. Van Asch CJ, Luitse MJ, Rinkel GJ, van der Tweel I, Algra A, Klijn CJ. Incidence, case fatality, and functional outcome of intracerebral haemorrhage over time, according to age, sex, and ethnic origin: a systematic review and meta-analysis. Lancet Neurol. 2010;9(2):167- 176.
12. 12. Rousseaux M, Hurtevent JF, Benaim C, Cassim F. Late contralateral hyperhidrosis in lateral medullary infarcts. Stroke. 1996;27(5):991- 995.
13. 13. Kim BS, Kim YI, Lee KS. Contralateral hyperhidrosis after cerebral infarction. Clinicoanatomic correlations in five cases. Stroke. 1995;26(5):896-899.
14. 14. Korpelainen JT, Sotaniemi KA, Myllylä VV. Asymmetric sweating in stroke: a prospective quantitative study of patients with hemispheral brain infarction. Neurology. 1993;43(6):1211-1214.
15. 15. Di Luca DG, Mohney NJ, Kottapally M. Paroxysmal sympathetic hyperactivity with dystoniafollowing non-traumatic bilateral thalamic and cerebellar hemorrhage. Neurocrit Care. 2019;30(3):688-689.
16. 16. Akbaş A, Kilinç F. Investigation on aetiological factors in patients with hyperhidrosis. Cutaneous Ocular Toxicology. 2018;37(4):344- 349.
17. 17. Cheshire WP, Fealey RD. Drug-induced hyperhidrosis and hypohidrosis: incidence, prevention and management. Drug Saf. 2008;31(2):109-126.
18. 18. Porzio G, Aielli F, Verna L, Porto C, Aloisi P, Cannita K, et al. Gabapentin in the treatment of severe sweating experienced by advanced cancer patients. Support Care Cancer. 2006;14(4):389- 391.
19. 19. Russo M, Graham B, Santarelli DM. Gabapentin-Friend or foe? Pain Pract. 2023;23(1):63-69.