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Türkiye'nin Doğu Karadeniz Bölgesindeki Balların Fizikokimyasal, Biyoaktif Bileşenleri ve Biyolojik Aktivitelerinin Karşılaştırılması

Yıl 2025, Cilt: 8 Sayı: 2, 143 - 174, 31.12.2025
https://doi.org/10.35206/jan.1662563

Öz

Bu çalışmanın amacı, Türkiye'deki bazı bal örneklerinin fizikokimyasal ve biyolojik karakterizasyonunu belirlemek ve karşılaştırmaktır. Bal örneklerinin Türk Gıda Kodeksine uygunluğu fizikokimyasal testlerle araştırılmıştır. Fenolik bileşenler RP- HPLC-PDA ile analiz edilmiştir. Örneklerin toplam fenolik ve flavonoid içeriği (TPC, TFC), antioksidan kapasitesi (FRAP, DPPH), üreaz, glukoz-oksidaz ve antimikrobiyal aktivitesi (Disk difüzyon, MIC) belirlenmiş ve FTIR ve UV-Vis analizleri yapılmıştır. Bal örneklerinin spektrumları, minör bileşenlerin fonksiyonel gruplarına karşılık gelen karakteristik bantları ortaya çıkarmıştır. Fizikokimyasal analizler sonucunda, incelenen örneklerin bir kısmının incelenen parametreler açısından Türk Gıda Kodeksi'nde tanımlanan standart değerlere uymadığı tespit edilmiştir. Spektral bulgular, bal örneklerinin zengin bir kimyasal bileşime sahip olduğunu göstermektedir. Anzer balı, zengin fenolik ve antioksidan içeriği ve nispeten yüksek antimikrobiyal aktivitesi ile diğer türlere tercih edilmektedir.

Kaynakça

  • Acar, V. (2021). Orta Asya Türklerinde bal ve balın tıbbi amaçlı kullanımı (Apiterapi). Mersin Üniversitesi Tıp Fakültesi Lokman Hekim Tıp Tarihi ve Folklorik Tıp Dergisi, 11(3), 612-624.
  • Acquarone, C., Buera, P., Elizalde, B. (2007). Pattern of pH and electrical conductivity upon honey dilution as a complementary tool for discriminating geographical origin of honeys. Food Chemistry, 101(2), 695-703.
  • Akgün, N., Çelik, Ö. F., & Kelebekli, L. (2021). Physicochemical properties, total phenolic content, and antioxidant activity of chestnut, rhododendron, acacia and multifloral honey. Journal of Food Measurement and Characterization, 15(4), 3501-3508.
  • Aksoy, Z. & Diğrak, M. (2006). Bingöl Yöresinde Toplanan Bal Ve Propolisin Antimikrobiyal Etkisi Üzerinde In Vitro Araştırmalar. Science and Engineering Journal of Fırat University, 18 (4), 471-478.
  • Alan, Y., Atalan, E., Erbil, N., Bakir, O., Orman, Z., Kanik, P. (2014). Antimicrobial Activity of Honey and Propolis Collected In Muş and Bitlis Region, Muş Alparslan University Journal of Science, 2 (1), 221-229.
  • Alothman, M., Bhat, R., Karim, A. A. (2009). Effect of radiation processing on phytochemicals and antioxidants in plant produce. Trends in Food Science & Technology, 20(4), 201–212.
  • Ajlouni, S. & Sujirapinyokul, P. (2010). Hydroxymethylfurfuraldehyde and amylase contents in Australian honey. Food Chemistry, 119(3), 1000-1005. https://doi.org/10.1016/j.foodchem.2009.07.057
  • Andrade, P., Ferreres F, Gil MI, Tomás-Barberán FA. (1997). Determination of phenolic compounds in honeys with different floral origin by capillary zone electrophoresis. Food Chemistry, 1, 79-81.
  • Ateş, Y., & Yaşar, S. (2020). Chemical investigations on honey produced in Bingol and surroundings. Uludag Aricilik Dergisi, 20(1), 72-80.
  • Bayram, N. (2021). Vitamin, mineral, polyphenol, amino acid profile of bee pollen from Rhododendron ponticum (source of “mad honey”): nutritional and 55 palynological approach. Journal of Food Measurement and Characterization, 15(3), 2659-2666.
  • Benzie, I. F. & Strain, J. J. (1996). The ferric reducing ability of plasma (FRAP) as a measure of “antioxidant power”: the FRAP assay. Analitic biochemistry, 239(1), 70-76.
  • Bilgen Çınar S. (2010). Analytical Properties of Turkish Pine Honey (Master's Thesis) Available from Council of Higher Education and Theses database. (Thesis No. 297529)
  • Bogdanov, S., Martin, P., Lullmann, C. (2002). Harmonised methods of the international honey commission. Swiss Bee Research Centre FAM Liebefeld, 5, 1-62.
  • Campos, M., Markham, K. R., Mitchell, K. A., da Cunha, A. P. (1997). An approach to the characterization of bee pollens via their flavonoid/phenolic profiles. Phytochemical Analysis, 8(4), 181-185.
  • Can, Z. & Baltas, N. (2016). Bioactivity and enzyme inhibition properties of Stevia rebaudiana. Current Enzyme Inhibition, 12(2), 188-194.
  • Can, Z., Yildiz, O., Sahin, H., Turumtay, E.A., Silici, S. & Kolayli, S. (2015). An investigation of Turkish honeys: their physico-chemical properties, antioxidant capacities and phenolic profiles. Food Chemistry, 180, 133-141. https://doi.org/10.1016/j.foodchem.2015.02.024
  • Chan‐Zapata, I. & Segura‐Campos, M. R. (2021). Honey and its protein components: Effects in the cancer immunology. Journal of Food Biochemistry, 45(5), e13613. https://doi.org/10.1111/jfbc.13613
  • CLSI (2018). Methods for dilution antimicrobial susceptibility tests for bacteria that grow aerobically. CLSI standard M7, 11th ed. Wayne PA. Clinical and Laboratory Standards Institute press, 1-91.
  • Codex Alimentarius, (2001). Revised Codex Standard for Honey, Codex Stand. 12–1981, revisions 1987 and 2001. Cozzolino, D. (2009). Near Infrared Spectroscopy in natural products analysis. Planta Medica, 75, 46-756. doi: https://doi.org/10.1055/s-0028-1112220
  • Çil, E. (2023). A Functional Food: Anzer Honey. In: Çakoğlu AH, Sancar MR, eds. Versalite Approaches to Engineering and Applied Sciences Material and Methods (pp. 99-105). Gaziantep, Özgür Publications.
  • Çol Ayvaz, M., Ömür, B., Ertürk, Ö. & Kabakçi, D. (2018). Phenolic profiles, antioxidant, antimicrobial, and DNA damage inhibitory activities of chestnut honeys from Black Sea Region of Turkey. Journal of Food Biochemistry, 42(3), e12502. https://doi.org/10.1111/jfbc.12502
  • Demirgül, F. (2018). Çadırdan saraya Türk mutfağı. Uluslararası Türk dünyası turizm araştırmaları dergisi, 3(1), 105-125.
  • Erdal, B. & Tipi, T. (2022). Time Series Forecasting of Honey Production in Turkey. European Journal of Science and Technology, 35, 417-423. https://doi.org/10.31590/ejosat.1066665
  • Flanjak, I., Strelec, I., Kenjeric, D., Primorac, L. (2016). Croatian produced unifloral honey characterized according to the protein and proline content and enzyme activities. Journal of Apicultural Research, 60(1), 39–48. https://doi.org/10.1515/jas-2016-0005.
  • Floegel, A., Boonprakob, U., Crospy, K., Cisneros-Zevallos, L. (2011). Comparison of DPPH, ABTS, FRAP, and ORAC assays for estimating antioxidant capacity from plasma samples. Clinical Biochemistry, 44(6), 391–394. https://doi.org/ 10.1016/j.clinbiochem.2010.12.011
  • Fukumoto, L.R. & Mazza, G. (2000). Assessing antioxidant and prooxidant activities of phenolic compounds. Journal of Agricultural & Food Chemistry, 48, 3597–3604.
  • Hançer, A. T., & Yılmaz, P. (2019). Balın Yara İyileşmesi Üzerine Etkisinin Değerlendirilmesi. Bozok Tıp Dergisi. https://doi.org/10.16919/bozoktip.399768
  • Hotaman, H. E. (2015). Investigation of some bioactive properties of anzer honey and pollen in vitro (Master's thesis). Available from Council of Higher Education and Theses database. (Thesis No. 394005)
  • Hudzicki, J. (2009). Kirby-Bauer disk diffusion susceptibility test protocol. American Society for Microbiology, 15, 55-63.
  • Kadiroğlu, A. (2024). Türkiye’de Doğal Bal Üretimi ve İhracat Performansı. Journal of BinBee Apicultural and Natural Products, 1-8.
  • Karadag, A., Ozcelik, B., Saner, S. (2009). Review of methods to determine antioxidant capacities. Food Analytical Methods, 2, 41–60. https://doi.org/10.1007/s12161-008-9067-7
  • Kaya, S. Y, & Yayla, F. (2020). Resmi Verilere Göre Türkiye’de Taklit ve Tağşiş Yapılan Yiyecek ve İçecekler. Journal of Tourism and Gastronomy Studies, 8(4), 3108-3128.
  • Kim, K. H, Tsao, R., Yang, R., Cui, S. W. (2006). Phenolic acid profiles and antioxidant activities of wheat bran extracts and the effect of hydrolysis conditions. Food Chemistry, 95(3), 466-473.
  • Küçük, M., Kolaylı, S., Karaoğlu, S., Ulusoy, E., Baltacı, C. & Candan, F. (2007). Biological activities and chemical composition of three honeys of different types from Anatolia. Food Chemistry, 100, 526-534. https://doi.org/10.1016/j.foodchem.2005.10.010
  • Kolayli, S., Can, Z., Yildiz, O., Sahin, H., Karaoglu, S. A. (2016). comparative study of the antihyaluronidase, antiurease, antioxidant, antimicrobial and physicochemical properties of different unifloral degrees of chestnut (Castanea sativa Mill.) honeys. Journal of Enzyme Inhibition and Medicinal Chemistry, 31(sup3), 96-104.
  • Malkoç, M., Çakır, H., Yakup, K., Zehra, C., Kolaylı, S. (2019). Phenolic composition and antioxidant properties of Anzer honey from black sea region of Turkey. Uludağ Bee Journal, 19(2), 143-151.
  • Meda, A., Lamien, C. E., Romito, M., Millogo, J., Nacoulma, O. G. (2005). Determination of the total phenolic, flavonoid, and proline contents in Burki G. Jacobo-Velázquez na Fasan honey, as well as their radical scavenging activity. Food Chemistry, 91(4), 571–577.
  • Molyneux, P., (2004). The use of the stable free radical diphenylpicrylhydrazyl (DPPH) for estimating antioxidant activity. Songklanakarin Journal Science and Technology, 26, 211–219.
  • Oddo, L. P., Piro, R., Bruneau, É., Guyot-Declerck, C., Ivanov, T., Piskulová, J. et al. (2004). Main European unifloral honeys: descriptive sheets. Apidologie, 35(Suppl. 1), S38-S81.
  • Parri, E., Santinami, G., Domenici, V. (2020). Front-Face Fluorescence of Honey of Different Botanic Origin: A Case Study from Tuscany (Italy). Applied Sciences, 10(5), 1776. https://doi.org/10.3390/app10051776
  • Quast, L. B., Zanette, M., Zanella Pinto, V., Passos Francisco, C., Quast, E., Felicetti, M. A. et al. (2022). Co-crystallized Honey with Sucrose: Storage Evaluation and Sensory Acceptance. Journal of Culinary Science & Technology, 20(2), 117-133. https://doi.org/10.1080/15428052.2020.1815628
  • Renuka, B., Sanjeev, B., Ranganathan, D. (2016). Evaluation of phytoconstituents of Caralluma nilagiriana by FTIR and UV-VIS spectroscopic analysis. Journal of Pharmacognosy and Phytochemistry, 5,105-108. https://doi.org/0.5530/pj.2015.3.4
  • Sánchez-Rangel, J. C., Benavides, D., Heredia, M., Cisneros-Zevallos, E., Jacobo-Velázquez, G. (2013). The antioxidant and phenolic content of different plant-based foods are not always positively correlated. Food Chemistry, 138(1), 257–264. https://doi.org/10.1016/j.foodchem.2012.10.089
  • Silici, S., Sagdic, O., Ekici, L. (2010). Total Phenolic Content, Antiradical, Antioxidant and Antimicrobial Activities of Rhododendron Honeys, Food Chemistry, 121, 238-243.
  • Singh, N. & Bath, P. K. (1997). Quality evaluation of different types of Indian honey. Food Chemistry, 58(1-2), 129-133. Slinkard, K. & Singleton, V. L. (1977). Total phenol analysis: automation and comparison with manual methods. American Journal of Enology and Viticulture, 28(1), 49-55.
  • Simsek, A., Bilsel, M., Goren, A. C. (2012). 13C/12C pattern of honey from Turkey and determination of adulteration in commercially available honey samples using EA-IRMS. Food Chemistry, 130(4), 1115-1121.
  • Şahin, G. (2019). Research on the chemical composition of some honeys (Master’s Thesis). Available from Council of Higher Education and Theses database. (Thesis No. 593901)
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Comparison of Honey's Physicochemical, Bioactive Components, and Biological Activities from the Eastern Black Sea Region of Türkiye

Yıl 2025, Cilt: 8 Sayı: 2, 143 - 174, 31.12.2025
https://doi.org/10.35206/jan.1662563

Öz

The aim of this study is to determine and compare the physicochemical and biological characterization of some honey samples in the Eastern Black Sea Region of Türkiye. Physicochemical tests investigated the compliance of honey samples with the Turkish Food Codex. The phenolic components were analyzed by RP- HPLC-PDA. The total phenolic and flavonoid contents (TPC, TFC), antioxidant capacity (FRAP, DPPH), urease, glucose-oxidase, and antimicrobial activity (Disc diffusion, MIC) of the samples were determined, and FTIR and UV-Vis analyses were conducted. The spectra of the honey samples revealed the characteristic bands corresponding to the functional groups of minor components. As a result of the physicochemical analyses, it was determined that some of the samples examined did not comply with the standard values defined in the Turkish Food Codex in terms of the examined parameters. Spectral findings show that honey samples have a rich chemical composition. Anzer honey is preferable to other kinds with its rich phenolic and antioxidant content and relatively high antimicrobial activity.

Kaynakça

  • Acar, V. (2021). Orta Asya Türklerinde bal ve balın tıbbi amaçlı kullanımı (Apiterapi). Mersin Üniversitesi Tıp Fakültesi Lokman Hekim Tıp Tarihi ve Folklorik Tıp Dergisi, 11(3), 612-624.
  • Acquarone, C., Buera, P., Elizalde, B. (2007). Pattern of pH and electrical conductivity upon honey dilution as a complementary tool for discriminating geographical origin of honeys. Food Chemistry, 101(2), 695-703.
  • Akgün, N., Çelik, Ö. F., & Kelebekli, L. (2021). Physicochemical properties, total phenolic content, and antioxidant activity of chestnut, rhododendron, acacia and multifloral honey. Journal of Food Measurement and Characterization, 15(4), 3501-3508.
  • Aksoy, Z. & Diğrak, M. (2006). Bingöl Yöresinde Toplanan Bal Ve Propolisin Antimikrobiyal Etkisi Üzerinde In Vitro Araştırmalar. Science and Engineering Journal of Fırat University, 18 (4), 471-478.
  • Alan, Y., Atalan, E., Erbil, N., Bakir, O., Orman, Z., Kanik, P. (2014). Antimicrobial Activity of Honey and Propolis Collected In Muş and Bitlis Region, Muş Alparslan University Journal of Science, 2 (1), 221-229.
  • Alothman, M., Bhat, R., Karim, A. A. (2009). Effect of radiation processing on phytochemicals and antioxidants in plant produce. Trends in Food Science & Technology, 20(4), 201–212.
  • Ajlouni, S. & Sujirapinyokul, P. (2010). Hydroxymethylfurfuraldehyde and amylase contents in Australian honey. Food Chemistry, 119(3), 1000-1005. https://doi.org/10.1016/j.foodchem.2009.07.057
  • Andrade, P., Ferreres F, Gil MI, Tomás-Barberán FA. (1997). Determination of phenolic compounds in honeys with different floral origin by capillary zone electrophoresis. Food Chemistry, 1, 79-81.
  • Ateş, Y., & Yaşar, S. (2020). Chemical investigations on honey produced in Bingol and surroundings. Uludag Aricilik Dergisi, 20(1), 72-80.
  • Bayram, N. (2021). Vitamin, mineral, polyphenol, amino acid profile of bee pollen from Rhododendron ponticum (source of “mad honey”): nutritional and 55 palynological approach. Journal of Food Measurement and Characterization, 15(3), 2659-2666.
  • Benzie, I. F. & Strain, J. J. (1996). The ferric reducing ability of plasma (FRAP) as a measure of “antioxidant power”: the FRAP assay. Analitic biochemistry, 239(1), 70-76.
  • Bilgen Çınar S. (2010). Analytical Properties of Turkish Pine Honey (Master's Thesis) Available from Council of Higher Education and Theses database. (Thesis No. 297529)
  • Bogdanov, S., Martin, P., Lullmann, C. (2002). Harmonised methods of the international honey commission. Swiss Bee Research Centre FAM Liebefeld, 5, 1-62.
  • Campos, M., Markham, K. R., Mitchell, K. A., da Cunha, A. P. (1997). An approach to the characterization of bee pollens via their flavonoid/phenolic profiles. Phytochemical Analysis, 8(4), 181-185.
  • Can, Z. & Baltas, N. (2016). Bioactivity and enzyme inhibition properties of Stevia rebaudiana. Current Enzyme Inhibition, 12(2), 188-194.
  • Can, Z., Yildiz, O., Sahin, H., Turumtay, E.A., Silici, S. & Kolayli, S. (2015). An investigation of Turkish honeys: their physico-chemical properties, antioxidant capacities and phenolic profiles. Food Chemistry, 180, 133-141. https://doi.org/10.1016/j.foodchem.2015.02.024
  • Chan‐Zapata, I. & Segura‐Campos, M. R. (2021). Honey and its protein components: Effects in the cancer immunology. Journal of Food Biochemistry, 45(5), e13613. https://doi.org/10.1111/jfbc.13613
  • CLSI (2018). Methods for dilution antimicrobial susceptibility tests for bacteria that grow aerobically. CLSI standard M7, 11th ed. Wayne PA. Clinical and Laboratory Standards Institute press, 1-91.
  • Codex Alimentarius, (2001). Revised Codex Standard for Honey, Codex Stand. 12–1981, revisions 1987 and 2001. Cozzolino, D. (2009). Near Infrared Spectroscopy in natural products analysis. Planta Medica, 75, 46-756. doi: https://doi.org/10.1055/s-0028-1112220
  • Çil, E. (2023). A Functional Food: Anzer Honey. In: Çakoğlu AH, Sancar MR, eds. Versalite Approaches to Engineering and Applied Sciences Material and Methods (pp. 99-105). Gaziantep, Özgür Publications.
  • Çol Ayvaz, M., Ömür, B., Ertürk, Ö. & Kabakçi, D. (2018). Phenolic profiles, antioxidant, antimicrobial, and DNA damage inhibitory activities of chestnut honeys from Black Sea Region of Turkey. Journal of Food Biochemistry, 42(3), e12502. https://doi.org/10.1111/jfbc.12502
  • Demirgül, F. (2018). Çadırdan saraya Türk mutfağı. Uluslararası Türk dünyası turizm araştırmaları dergisi, 3(1), 105-125.
  • Erdal, B. & Tipi, T. (2022). Time Series Forecasting of Honey Production in Turkey. European Journal of Science and Technology, 35, 417-423. https://doi.org/10.31590/ejosat.1066665
  • Flanjak, I., Strelec, I., Kenjeric, D., Primorac, L. (2016). Croatian produced unifloral honey characterized according to the protein and proline content and enzyme activities. Journal of Apicultural Research, 60(1), 39–48. https://doi.org/10.1515/jas-2016-0005.
  • Floegel, A., Boonprakob, U., Crospy, K., Cisneros-Zevallos, L. (2011). Comparison of DPPH, ABTS, FRAP, and ORAC assays for estimating antioxidant capacity from plasma samples. Clinical Biochemistry, 44(6), 391–394. https://doi.org/ 10.1016/j.clinbiochem.2010.12.011
  • Fukumoto, L.R. & Mazza, G. (2000). Assessing antioxidant and prooxidant activities of phenolic compounds. Journal of Agricultural & Food Chemistry, 48, 3597–3604.
  • Hançer, A. T., & Yılmaz, P. (2019). Balın Yara İyileşmesi Üzerine Etkisinin Değerlendirilmesi. Bozok Tıp Dergisi. https://doi.org/10.16919/bozoktip.399768
  • Hotaman, H. E. (2015). Investigation of some bioactive properties of anzer honey and pollen in vitro (Master's thesis). Available from Council of Higher Education and Theses database. (Thesis No. 394005)
  • Hudzicki, J. (2009). Kirby-Bauer disk diffusion susceptibility test protocol. American Society for Microbiology, 15, 55-63.
  • Kadiroğlu, A. (2024). Türkiye’de Doğal Bal Üretimi ve İhracat Performansı. Journal of BinBee Apicultural and Natural Products, 1-8.
  • Karadag, A., Ozcelik, B., Saner, S. (2009). Review of methods to determine antioxidant capacities. Food Analytical Methods, 2, 41–60. https://doi.org/10.1007/s12161-008-9067-7
  • Kaya, S. Y, & Yayla, F. (2020). Resmi Verilere Göre Türkiye’de Taklit ve Tağşiş Yapılan Yiyecek ve İçecekler. Journal of Tourism and Gastronomy Studies, 8(4), 3108-3128.
  • Kim, K. H, Tsao, R., Yang, R., Cui, S. W. (2006). Phenolic acid profiles and antioxidant activities of wheat bran extracts and the effect of hydrolysis conditions. Food Chemistry, 95(3), 466-473.
  • Küçük, M., Kolaylı, S., Karaoğlu, S., Ulusoy, E., Baltacı, C. & Candan, F. (2007). Biological activities and chemical composition of three honeys of different types from Anatolia. Food Chemistry, 100, 526-534. https://doi.org/10.1016/j.foodchem.2005.10.010
  • Kolayli, S., Can, Z., Yildiz, O., Sahin, H., Karaoglu, S. A. (2016). comparative study of the antihyaluronidase, antiurease, antioxidant, antimicrobial and physicochemical properties of different unifloral degrees of chestnut (Castanea sativa Mill.) honeys. Journal of Enzyme Inhibition and Medicinal Chemistry, 31(sup3), 96-104.
  • Malkoç, M., Çakır, H., Yakup, K., Zehra, C., Kolaylı, S. (2019). Phenolic composition and antioxidant properties of Anzer honey from black sea region of Turkey. Uludağ Bee Journal, 19(2), 143-151.
  • Meda, A., Lamien, C. E., Romito, M., Millogo, J., Nacoulma, O. G. (2005). Determination of the total phenolic, flavonoid, and proline contents in Burki G. Jacobo-Velázquez na Fasan honey, as well as their radical scavenging activity. Food Chemistry, 91(4), 571–577.
  • Molyneux, P., (2004). The use of the stable free radical diphenylpicrylhydrazyl (DPPH) for estimating antioxidant activity. Songklanakarin Journal Science and Technology, 26, 211–219.
  • Oddo, L. P., Piro, R., Bruneau, É., Guyot-Declerck, C., Ivanov, T., Piskulová, J. et al. (2004). Main European unifloral honeys: descriptive sheets. Apidologie, 35(Suppl. 1), S38-S81.
  • Parri, E., Santinami, G., Domenici, V. (2020). Front-Face Fluorescence of Honey of Different Botanic Origin: A Case Study from Tuscany (Italy). Applied Sciences, 10(5), 1776. https://doi.org/10.3390/app10051776
  • Quast, L. B., Zanette, M., Zanella Pinto, V., Passos Francisco, C., Quast, E., Felicetti, M. A. et al. (2022). Co-crystallized Honey with Sucrose: Storage Evaluation and Sensory Acceptance. Journal of Culinary Science & Technology, 20(2), 117-133. https://doi.org/10.1080/15428052.2020.1815628
  • Renuka, B., Sanjeev, B., Ranganathan, D. (2016). Evaluation of phytoconstituents of Caralluma nilagiriana by FTIR and UV-VIS spectroscopic analysis. Journal of Pharmacognosy and Phytochemistry, 5,105-108. https://doi.org/0.5530/pj.2015.3.4
  • Sánchez-Rangel, J. C., Benavides, D., Heredia, M., Cisneros-Zevallos, E., Jacobo-Velázquez, G. (2013). The antioxidant and phenolic content of different plant-based foods are not always positively correlated. Food Chemistry, 138(1), 257–264. https://doi.org/10.1016/j.foodchem.2012.10.089
  • Silici, S., Sagdic, O., Ekici, L. (2010). Total Phenolic Content, Antiradical, Antioxidant and Antimicrobial Activities of Rhododendron Honeys, Food Chemistry, 121, 238-243.
  • Singh, N. & Bath, P. K. (1997). Quality evaluation of different types of Indian honey. Food Chemistry, 58(1-2), 129-133. Slinkard, K. & Singleton, V. L. (1977). Total phenol analysis: automation and comparison with manual methods. American Journal of Enology and Viticulture, 28(1), 49-55.
  • Simsek, A., Bilsel, M., Goren, A. C. (2012). 13C/12C pattern of honey from Turkey and determination of adulteration in commercially available honey samples using EA-IRMS. Food Chemistry, 130(4), 1115-1121.
  • Şahin, G. (2019). Research on the chemical composition of some honeys (Master’s Thesis). Available from Council of Higher Education and Theses database. (Thesis No. 593901)
  • Tezcan, F., Kolaylı, S., Sahin, H., Ulusoy, E., Erim, B. F. (2011). Evaluation of organic acid, saccharide composition and antioxidant properties of some authentic Turkish honeys. Journal of Food Nutrion Research, 50, 33-40.
  • Tolon, B. (1999). A Research on Biochemical Properties of Muğla and Its Region Pine Honey (PhD thesis). Available from Council of Higher Education and Theses database. (Thesis No. 85720)
  • TS 3036, (2002). Turkish Standards Institute Honey Standard, Ankara.
  • TS 13360, (2008). Turkish Standards Institute Determination of Free Acidity of Honey, Ankara.
  • TS 13359, (2008). Determination of fructose, glucose, saccharose, turanose and maltose of honey by high performance liquid chramatography Ankara.
  • TS 13366, (2008). Turkish Standards Institute Determining Electrical Conductivity of Honey Ankara.
  • TS 13364, (2008). Determining the Diastase Activity of Honey. Ankara.
  • Türk Patent ve Marka Kurumu (2024). Coğrafi İşaretler Portalı. ci.turkpatent.gov.tr/ (Erişim Tarihi: 5 Mart 2024).
  • TÜİK (Türkiye istatistik kurumu) haber bülteni (2025). Türkiye hayvansal üretim istatistikkleri 2024.https://data.tuik.gov.tr/Bulten/Index?p=Hayvansal-%C3%9Cretim-%C4%B0statistikleri-2024-53935&dil=1. (Erişim 20 Mayıs 2025).
  • Uslu, A. N. (2024). Türk Mutfak Kültüründe Bal ve Türkiye’de Yer Alan Coğrafi İşaretli Ballar Üzerine Bir Araştırma.
  • Uluslararası Türk Dünyası Turizm Araştırmaları Dergisi, 9(1), 75-93. https://doi.org/10.37847/tdtad.1458646 White, Jr J. W. (1957). The composition of honey. Bee World, 38(3), 57-66.
  • Weatherburn, M. W. (1967). Phenol-hypo-chloritere action for determination of ammonia. Analitic Chemistry, 39(8), 971-974.
  • Yıldırım, E. A., Kılıç, N. K., & Özkan, N. G. (2021). Pollen analysis of honeys from Yığılca region (Düzce), Turkey. Eurasian Journal of Forest Science, 9(3), 259-271.
  • Yildiz, O., Karahalil, F., Can, Z., Sahin, H., Kolayli, S. (2014). Total monoamine oxidase (MAO) inhibition by chestnut honey, pollen and propolis. Journal of Enzyme inhibition and Medicinal Chemistry, 29(5), 690-694.
Toplam 61 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Konular Kimya Mühendisliği (Diğer)
Bölüm Araştırma Makalesi
Yazarlar

Demet Çavuş 0000-0001-6449-0334

Ömer Ertürk 0000-0001-5837-6893

Elif Çil 0000-0003-1420-8729

Zehra Can 0000-0002-9366-5110

Emine Bağdatlı 0000-0001-5946-2988

Gönderilme Tarihi 21 Mart 2025
Kabul Tarihi 5 Ağustos 2025
Yayımlanma Tarihi 31 Aralık 2025
Yayımlandığı Sayı Yıl 2025 Cilt: 8 Sayı: 2

Kaynak Göster

APA Çavuş, D., Ertürk, Ö., Çil, E., … Can, Z. (2025). Comparison of Honey’s Physicochemical, Bioactive Components, and Biological Activities from the Eastern Black Sea Region of Türkiye. Journal of Apitherapy and Nature, 8(2), 143-174. https://doi.org/10.35206/jan.1662563
AMA Çavuş D, Ertürk Ö, Çil E, Can Z, Bağdatlı E. Comparison of Honey’s Physicochemical, Bioactive Components, and Biological Activities from the Eastern Black Sea Region of Türkiye. Journal of Apitherapy and Nature. Aralık 2025;8(2):143-174. doi:10.35206/jan.1662563
Chicago Çavuş, Demet, Ömer Ertürk, Elif Çil, Zehra Can, ve Emine Bağdatlı. “Comparison of Honey’s Physicochemical, Bioactive Components, and Biological Activities from the Eastern Black Sea Region of Türkiye”. Journal of Apitherapy and Nature 8, sy. 2 (Aralık 2025): 143-74. https://doi.org/10.35206/jan.1662563.
EndNote Çavuş D, Ertürk Ö, Çil E, Can Z, Bağdatlı E (01 Aralık 2025) Comparison of Honey’s Physicochemical, Bioactive Components, and Biological Activities from the Eastern Black Sea Region of Türkiye. Journal of Apitherapy and Nature 8 2 143–174.
IEEE D. Çavuş, Ö. Ertürk, E. Çil, Z. Can, ve E. Bağdatlı, “Comparison of Honey’s Physicochemical, Bioactive Components, and Biological Activities from the Eastern Black Sea Region of Türkiye”, Journal of Apitherapy and Nature, c. 8, sy. 2, ss. 143–174, 2025, doi: 10.35206/jan.1662563.
ISNAD Çavuş, Demet vd. “Comparison of Honey’s Physicochemical, Bioactive Components, and Biological Activities from the Eastern Black Sea Region of Türkiye”. Journal of Apitherapy and Nature 8/2 (Aralık2025), 143-174. https://doi.org/10.35206/jan.1662563.
JAMA Çavuş D, Ertürk Ö, Çil E, Can Z, Bağdatlı E. Comparison of Honey’s Physicochemical, Bioactive Components, and Biological Activities from the Eastern Black Sea Region of Türkiye. Journal of Apitherapy and Nature. 2025;8:143–174.
MLA Çavuş, Demet vd. “Comparison of Honey’s Physicochemical, Bioactive Components, and Biological Activities from the Eastern Black Sea Region of Türkiye”. Journal of Apitherapy and Nature, c. 8, sy. 2, 2025, ss. 143-74, doi:10.35206/jan.1662563.
Vancouver Çavuş D, Ertürk Ö, Çil E, Can Z, Bağdatlı E. Comparison of Honey’s Physicochemical, Bioactive Components, and Biological Activities from the Eastern Black Sea Region of Türkiye. Journal of Apitherapy and Nature. 2025;8(2):143-74.
  • 23484   ASOS Index