Kawasaki Hastalığı ile Rhinovirüs Enfeksiyonu Birlikteliği

Öz

Kawasaki hastalığı KH , sıklıkla 5 yaş altı çocuklarda gözlenen akut, sistemik ve ateşli bir hastalıktır. Etiyolojisi tam olarak bilinmemekle birlikte, genetik yatkınlığı olan bireylerde olası bir enfeksiyöz ajanın varlığı suçlanmakta- dır. Hastalığın enfeksiyon hastalıklarına benzer şekilde bulgu vermesi, belirli mevsimlerde ve bazı coğrafi bölge- lerde daha sık gözlenmesi enfeksiyöz etken varlığını güç- lendirmektedir. Başta, Parvovirus B19, Epstein-Barr Virus EBV , Cytomegalovirus CMV ve mikoplazma gibi çok sayıda etkenin KH ile ilişkili olabileceği düşünülmektedir. Biz de burada viral solunum panelinde Rhinovirus pozitif- liği ile beraber Kawasaki hastalığı bulunan 2 yaş kız vaka- yı sunmak istedik

Anahtar Kelimeler

• Çocuk,Kawasaki hastalığı,Rhinovirus enfeksiyonu

Concomitancy Between Rhinovirus Infection and Kawasaki Disease

Öz

Kawasaki disease KD is an acute, systemic, febrile disease which is mostly encountered in children under age of 5. Although the underlying etiology is not fully known, the pre- sence of an infectious agent in patients with genetic predispo- sition is often blamed. Clinical findings consistent with infec- tious diseases and high incidence during particular seasons on particular geographical regions reinforce the possibility of infectious agent. Numerous infectious agents including Parvovirus B19, Epstein-Barr Virus EBV , Cytomegalovirus CMV and Mycoplasma are the most common infectious agents related with KD. Herein we want to present our 2-year- old female child with Kawasaki disease associated with Rhinovirus infection positivity

Anahtar Kelimeler

• Child,Kawasaki disease,Rhinovirus infection

Kaynakça

1. 1. Burns JC, Glodé MP. Kawasaki syndrome. Lancet 2004;9433:533-44. http://dx.doi.org/10.1016/S0140-6736(04)16814-1
2. 2. Kawasaki T. Acute febrile mucocutaneous syndrome with lymphoid involvement with specific desquamation of the fingers and toes in children. Arerugi 1967;16:178-222.
3. 3. Wolff AE, Hansen KE, Zakowski L. Acute Kawasaki disease: not just for kids. J Gen Intern Med 2007;22:681-4. http://dx.doi.org/10.1007/s11606-006-0100-5
4. 4. Yavuz T, Nişli K, Öner N ve ark. Kawasaki Hastalığı: 34 vaka sunumu. Turk Pediatri Ars 2006;41:197-200.
5. 5. Demir M, Keceoğlu S, Melek M. The relationship between plasma eosinophil count and coronary artery ectasia. Cardiol Res 2013;4:159-64. http://dx.doi.org/10.4021/cr280w
6. 6. Atarod L, Aghighi Y, Akbari P. Relationship between eosinophilia & coronary artery lesions in Kawasaki disease: a survey in Imam Khomeini Hospital. Tehran Univ Med J 2008: 24-9.
7. 7. Uchiyama T, Kato H. The pathogenesis of kawasaki disease and superantigens. Jpn J Infect Dis 1999;52:141.
8. 8. Keren G, Barzilay A, Alpert G, et al. Mucocutaneous lymph node syndrome (Kawasaki disease) Israel. A review of 13 cases: Is pseudomonas infection responsible? Acta Pediatr Scand 1983;72:455. http://dx.doi.org/10.1111/j.1651-2227.1983.tb09746.x

9. 9. Chang LY, Chang IS, Lu CY, Chiang BL, Lee CY, Chen PJ, et al. Epidemiological features of Kawasaki disease in Taiwan from 1996 to 2002. Pediatrics 2004;114:678-82. http://dx.doi.org/10.1542/peds.2004-0726
10. 10. Chang LY, Lu CY, Shao PL et al. Viral infections associated with Kawasaki disease. J Formos Med Assoc 2014;113:148- 54. http://dx.doi.org/10.1016/j.jfma.2013.12.008