Çocukluk Çağı Tiroid Papiller Karsinomu Vakası

Öz

Çocukluk çağında tiroid nodullerinin görülme sıklığı % 1-1.5 olup çoğunun benign olmasına karşılık birlikte çok küçük yaş, iyot eksikliği, baş ve boyuna radyasyon tedavisi uygulanmış olması ve muhtemel otoimmün tiroidit varlığı malignite riskini artırmaktadır. Bu makalede boyunda şişlik yakınması ile başvuran ve incelemeler sonucunda papiller tiroid karsinom tespit edilen 10 yaşında bir vakayı sunacağız.

Anahtar Kelimeler

• Çocuk,papiller tiroid karsinomu,nodül,boyunda şişlik

A Case of Papillary Thyroid Carcinoma in Childhood

Öz

The incidence of childhood thyroid nodules is 1-1.5%. Although most thyroid nodules are benign, very young age, iodine deficiency, radiation therapy applied to the head and neck and the presence of autoimmune thyroiditis increase the risk of malignancy. We will present a ten-year girl with complaints of swelling in the neck. whose medical tests revealed the presence of a papillary thyroid carcinoma.

Anahtar Kelimeler

• Child,papillary thyroid carcinoma,nodules,swelling in the neck

Kaynakça

1. 1. Koç C. Pediyatrik boyun kitleleri. Klinik Pediatri 2002;1:62- 72.
2. 2. Tracy TF Jr, Muratore CS. Management of common head and neck masses. Semin Pediatr Surg 2007;16:3-13. http://dx.doi.org/10.1053/j.sempedsurg.2006.10.002 PMid:17210478
3. 3. Josefson J, Zimmerman D. Thyroid nodules and cancers in children. Pediatr Endocrinol Rev 2008;6:14-23. PMid:18806721
4. 4. LaFranchi S. Solitary thyroid nodule nelson textbook of pediatrics, 19th ed, Chapter 563.
5. 5. Niedziela M. Pathogenesis, diagnosis and management of thyroid nodules in children. Endocr Relat Cancer 2006;13:427- 453. http://dx.doi.org/10.1677/erc.1.00882 PMid:16728572
6. 6. Saavedra J, Deladoëy J, Saint-Vil D, Boivin Y, Alos N, Deal C, Van Vliet G, et al. Is ultrasonography useful in predicting thyroid cancer in children with thyroid nodules and apparently benign cytopathologic features? Horm Res Paediatr 2011;75:269-75. http://dx.doi.org/10.1159/000322877 PMid:21252476
7. 7. Intenzo CM, Dam HQ, Manzone TA, Kim SM. Imaging of the thyroid in benign and malignant disease. Semin Nucl Med 2012;42:49-61. http://dx.doi.org/10.1053/j.semnuclmed.2011.07.004 PMid:22117813
8. 8. Rosário PW, Salles DS, Bessa B, Purisch S. Contribution of scintigraphy and ultrasonography to the prediction of malignancy in thyroid nodules with indeterminate cytology. Arq Bras Endocrinol Metabol 2010;54:56-9. http://dx.doi.org/10.1590/S0004-27302010000100010

9. 9. Lugo-Vicente H, Ortíz VN, Irizarry H, Camps JI, Pagán V. Pediatric thyroid nodules: management in the era of fine needle aspiration. J Pediatr Surg 1998;33:1302-5. http://dx.doi.org/10.1016/S0022-3468(98)90174-9
10. 10. Vaisman F, Corbo R, Vaisman M. Thyroid carcinoma in children and adolescents-systematic review of the literature. J Thyroid Res 2011:845362.
11. 11. Corrias A, Cassio A, Weber G, et al. Thyroid nodules and cancer in children and adolescents affected by autoimmune thyroiditis. Arch Pediatr Adolesc Med 2008;162:526-31. http://dx.doi.org/10.1001/archpedi.162.6.526 PMid:18524742
12. 12. Mazokopakis EE, Tzortzinis AA, Dalieraki-Ott EI, Tsartsalis AN, Syros PK, Karefilakis CM, Papadomanolaki MG. Coexistence of Hashimoto’s thyroiditis with papillary thyroid carcinoma. A retrospective study. Hormones 2010;9:312-7. PMid:21112862
13. 13. Kim SS, Lee BJ, Lee JC, Kim SJ, Jeon YK, Kim MR, Huh JE, et al. Coexistence of Hashimoto’s thyroiditis with papillary thyroid carcinoma: the influence of lymph node metastasis. Head Neck 2011;33:1272-7. http://dx.doi.org/10.1002/hed.21594 PMid:21837696
14. 14. Kim EY, Kim WG, Kim WB, Kim TY, Kim JM, Ryu JS, Hong SJ et al. Coexistence of chronic lymphocytic thyroiditis is associated with lower recurrence rates in patients with papillary thyroid carcinoma. Clin Endocrinol 2009;71:581-6. http://dx.doi.org/10.1111/j.1365-2265.2009.03537.x PMid:19222495
15. 15. Pearce EN, Farwell AP, Braverman LE. Thyroiditis. N Engl J Med 2003;348:2646-55. http://dx.doi.org/10.1056/NEJMra021194 PMid:12826640