Romatolojik Acil Yumuşak Damak Felci Gelişen Jüvenil Polimiyozit ve Diğer Jüvenil Polimiyozit ve Dermatomiyozit Vakaları

Öz

Dermatomiyozit ve polimiyozit çocukluk çağında en sık görülen inflamatuvar kas hastalıklarındandır. Çocuklarda nadir olarak görülmesine karşın ciddi morbidite ve morta- lite nedenidir. Son yıllardaki tedavi için pek çok yeni ilaç geliştirme çabaları ve yeni ilaçlarla ilgili çalışmalar yayınlanmakta ise de, tedavisinde diğer romatolojik hasta- lıklarda kullanılan ilaçlar ve onkolojik ilaçlar kullanılmak- tadır. Kliniğimizde izlenen vakalarımız, Ender olarak görülmelerine karşın morbiditesi ve mortalitesi ağır olan bu hastalıkları hatırlatmak, tüm özellikleriyle tartışmak ve seyirleri sırasında romatolojik acil bir durum gelişebilece- ğini vurgulama amacıyla kliniğimizde izleyenenen vakalar sunuldu

Anahtar Kelimeler

• Juvenil polimiyozit,juvenil dermatomiyozit,romatolojik acil

Juvenile Polymyositis with Rheumatologic Emergency Soft Palate Paralysis and Other Cases with Juvenile Polymyositis, and Dermatomyositis

Öz

Dermatomyositis and polymyositis are the most common inflammatory myopathies of childhood. They are seen rarely in children but they cause important morbidity and mortality. Though in current years, new drug improve- ment strategies, and studies on new drugs are being published, drugs used for other rheumatological , and also oncological diseases are being used for their treat- ment. We present the patients followed up in our clinic to remind and discuss the features of these rarely seen dise- ases with serious morbidity and mortality, and also to emphasize that a rheumatologic emergency might emerge during their course

Anahtar Kelimeler

• Juvenile polymyositis,juvenile dermatomyositis,rheumatologic emergency

Kaynakça

1. Conte, CG, Steen, VD, Medsger, TA Jr. Incidence of polymyositis-dermatomyositis: a 20 -year study of hospital diagnosed cases in Allegheny County, PA 1963-1982 J Rheumatol 1990 17:1329. systemic connective tissue diseases in children: a nationwide prospective study in Finland. J Rheumatol 1994; 21:2143.
2. Symmons DP, Sills JA, Davis SM. The incidence of Juvenile dermatomyositis: results from a nationwide study. Br J Rheumatol 1995; 34:732. dence of juvenile dermatomyositis, 1995-1998: results from the National Institute of Arthritis and Musculoskeletal and Skin Diseases Registry. Arthritis Rheum 2003; 49:300.
3. Gardner-Medwin JM, Dolezalova P, Cummins C, Southwood TR. Incidence of Henoch-Schonlein purpura, Kawasaki disease, and rare vasculitides in children of diffe- rent ethnic origins. Lancet 2002; 360:1197. acquired metabolic myopathy. Curr Opin Rheumatol 2003; 15:675-8. Current Opin in Rheumatol 1995; 7:437-41. (second of two parts). N Engl J Med 1975; 292(8):403-7.
4. Bohan A, Peter JB. Polymyositis and dermatomyositis (first of two parts).
5. Christensen ML, Pachman LM, Schneiderman R, et al. Prevalence of Coxsackie B virus antibodies in patients with juvenile dermatomyositis. Arthritis Rheum 1986; 29:1365.
6. Al-Mayouf SM, Laxer RM, Schneider R, et al. Intravenous immunoglobulin therapy for juvenile dermatomyositis: effi- cacy and safety. J Rheumatol 2000; 27:2498-503. dermatomyositis:factors predicting functional outcome and development of dystrophic calcification. J Pediatr 1983; 103:882-8. juvenile dermatomyositis. J Pediatr 1984; 105:399-408.
7. Miller LC, Michael AF, Kim Y. Childhood dermatomyositis: clinical course and long-term follow-up. Clin Pediatr (Phila) 1987; 26:561-6.