1. DergiPark
  2. Çocuk Dergisi
  3. Arşiv
  4. Cilt 20, Sayı 3
Yıl 2020, Cilt 20 , Sayı 3, Sayfalar 100 - 106 2020-12-29

Comparison of Risk Factors and Neonatal Outcomes in Early-Onset and Late-Onset Preeclampsia
Erken ve Geç Başlangıçlı Preeklampside Risk Faktörleri ve Neonatal Sonuçların Karşılaştırılması

Özgül BULUT [1] , Meryem HOCAOĞLU [2] , Nurgül BULUT [3] , Selin DEMİRER [4] , Abdulkadir TURGUT [5] , Fahri OVALI [6]

Öz

Objective: To compare the maternal risk factors and early neonatal outcomes in early-onset and late-onset preeclampsia. Material and Methods: In our hospital, patients diagnosed with preeclampsia were evaluated retrospectively. The patients were divided into two groups as early onset preeclampsia (≤34 weeks) and late onset preeclampsia (>34 weeks). Statistical analyses were used to compare demographic data, maternal risk factors and neonatal outcomes between the two groups. Results: Out of 92 patients, 45 (49%) were in the early onset preeclampsia and 47 (51%) were in the late onset preeclampsia groups. Cesarean delivery and intrauterine growth retardation (IUGR) rates were significantly higher in the early onset preeclampsia group (p=0.01, p=0.025). High body mass index was an independent risk factor for late onset preeclampsia in the logistic regression analysis (p=0.012). Neonatal morbidities and hospitalization rates in the neonatal intensive care unit (NICU) were significantly higher in the early onset preeclampsia group (p<0.05, p=0.005, respectively). In addition, in the logistic regression analysis, it was found that early onset preeclampsia significantly increased the risks of IUGR (OR 2.96; 95% CL: 1.12–7.81), being small for gestational age (OR 2.5; 95% CL: 1.05–5.95), respiratory distress syndrome (OR 15.35; 95% CL: 3.06–76.99), patent ductus arteriosus (OR 11.43; 95% CL: 1.36–96.16) and hospitalization in the NICU (OR 2.48; 95% CL: 1.06–5.77). Conclusion: Early-onset preeclampsia was found to be an important risk factor for adverse neonatal outcomes while high body mass index during pregnancy was associated with late-onset preeclampsia.
Amaç: Erken başlangıçlı ve geç başlangıçlı preeklampside maternal risk faktörleri ve erken dönem neonatal sonuçların karşılaştırılması. Gereç ve Yöntem: Hastanemizde preeklampsi tanısı almış hastalar retrospektif olarak değerlendirildi. Hastalar erken başlangıçlı preeklampsi (≤34 hafta) ve geç başlangıçlı preeklampsi (>34 hafta) olmak üzere 2 gruba ayrıldı. İki grup arasında demografik data, maternal risk faktörleri ve neonatal sonuçları karşılaştırmak için istatistiksel analiz yapıldı. Bulgular: Preeklampsi tanısı alan 92 hastanın, 45 (%49)’i erken başlangıçlı preeklampsi ve 47 (%51)’si geç başlangıçlı preeklampsi idi. Erken başlangıçlı preeklampsi grubunda, sezaryen doğum ve intrauterin büyüme kısıtlılığı (İUBK) oranları anlamlı şekilde daha yüksek bulundu (p=0.01, p=0.025). Lojistik regresyon analizinde, gebelikte yüksek vücut kitle indeksinin geç başlangıçlı preeklampsi için bağımsız bir risk faktörü olduğu saptandı (p=0.012). Erken başlangıçlı preeklampsi grubunda, neonatal morbidite ve yenidoğan yoğun bakım ünitesine (YDYBÜ) yatış oranları anlamlı şekilde daha yüksek bulundu (p<0.05, p=0.005, sırasıyla). Bunun yanında, lojistik regresyon analizinde erken başlangıçlı preeklampsinin, İUBK (OR 2.96; 95% CL: 1.12–7.81), SGA (OR 2.5; 95% CL: 1.05–5.95), respiratuar distres sendromu (OR 15.34; 95% CL: 3.06–76.99), patent duktus arteriosus (OR 11.43; 95% CL: 1.36–96.16) ve YDYBÜ’ne yatış (OR 2.48; 95% CL: 1.06–5.77) riskini anlamlı şekilde artırdığı saptandı. Sonuç: Çalışmamızda, erken başlangıçlı preeklampsi, olumsuz neonatal sonuçlar için önemli bir risk faktörü olarak bulunurken, gebelikte yüksek vücut kitle indeksi geç başlangıçlı preeklampsi ile ilişkili bulundu.

Kaynakça

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Ayrıntılar

Birincil Dil en
Konular Pediatri
Bölüm Araştırma Makaleleri
Yazarlar

Orcid: 0000-0001-9939-7375
Yazar: Özgül BULUT (Sorumlu Yazar)
Kurum: Department of Pediatrics, Division of Neonatology, Istanbul Medeniyet University Goztepe Training and Research Hospital, Istanbul
Ülke: Turkey

Orcid: 0000-0002-1832-9993
Yazar: Meryem HOCAOĞLU
Kurum: Department of Obstetrics and Gynecology Clinic, Istanbul Medeniyet University Goztepe Training and Research Hospital, Istanbul
Ülke: Turkey

Orcid: 0000-0002-7247-6302
Yazar: Nurgül BULUT
Kurum: Department of Biostatistics and Medical Informatics, Istanbul Medeniyet University Goztepe Training and Research Hospital, Istanbul
Ülke: Turkey

Orcid: 0000-0002-5888-0835
Yazar: Selin DEMİRER
Kurum: Department of Genetics, Aziz Sancar Institute of Experimental Medicine, Istanbul University, Istanbul
Ülke: Turkey

Orcid: 0000-0002-3156-2116
Yazar: Abdulkadir TURGUT
Kurum: Department of Obstetrics and Gynecology Clinic, Istanbul Medeniyet University Goztepe Training and Research Hospital, Istanbul
Ülke: Turkey

Orcid: 0000-0002-9717-313X
Yazar: Fahri OVALI
Kurum: Department of Pediatrics, Division of Neonatology, Istanbul Medeniyet University Goztepe Training and Research Hospital, Istanbul
Ülke: Turkey
Tarihler

Yayımlanma Tarihi : 29 Aralık 2020

Kaynak Göster

Bibtex @araştırma makalesi { jchild809801, journal = {Çocuk Dergisi}, issn = {}, eissn = {1308-8491}, address = {Çocuk Dergisi Yayın Kurulu Sekreterliği İstanbul Tıp Fakültesi, Çocuk Sağlığı ve Hastalıkları Anabilim Dalı Çapa, 34390, İstanbul}, publisher = {İstanbul Üniversitesi}, year = {2020}, volume = {20}, pages = {100 - 106}, doi = {}, title = {Comparison of Risk Factors and Neonatal Outcomes in Early-Onset and Late-Onset Preeclampsia}, key = {cite}, author = {Bulut, Özgül and Hocaoğlu, Meryem and Bulut, Nurgül and Demi̇rer, Selin and Turgut, Abdulkadir and Ovalı, Fahri} }
APA Bulut, Ö , Hocaoğlu, M , Bulut, N , Demi̇rer, S , Turgut, A , Ovalı, F . (2020). Comparison of Risk Factors and Neonatal Outcomes in Early-Onset and Late-Onset Preeclampsia . Çocuk Dergisi , 20 (3) , 100-106 . Retrieved from https://dergipark.org.tr/tr/pub/jchild/issue/58892/809801
MLA Bulut, Ö , Hocaoğlu, M , Bulut, N , Demi̇rer, S , Turgut, A , Ovalı, F . "Comparison of Risk Factors and Neonatal Outcomes in Early-Onset and Late-Onset Preeclampsia" . Çocuk Dergisi 20 (2020 ): 100-106 <https://dergipark.org.tr/tr/pub/jchild/issue/58892/809801>
Chicago Bulut, Ö , Hocaoğlu, M , Bulut, N , Demi̇rer, S , Turgut, A , Ovalı, F . "Comparison of Risk Factors and Neonatal Outcomes in Early-Onset and Late-Onset Preeclampsia". Çocuk Dergisi 20 (2020 ): 100-106
RIS TY - JOUR T1 - Comparison of Risk Factors and Neonatal Outcomes in Early-Onset and Late-Onset Preeclampsia AU - Özgül Bulut , Meryem Hocaoğlu , Nurgül Bulut , Selin Demi̇rer , Abdulkadir Turgut , Fahri Ovalı Y1 - 2020 PY - 2020 N1 - DO - T2 - Çocuk Dergisi JF - Journal JO - JOR SP - 100 EP - 106 VL - 20 IS - 3 SN - -1308-8491 M3 - UR - Y2 - 2020 ER -
EndNote %0 Çocuk Dergisi Comparison of Risk Factors and Neonatal Outcomes in Early-Onset and Late-Onset Preeclampsia %A Özgül Bulut , Meryem Hocaoğlu , Nurgül Bulut , Selin Demi̇rer , Abdulkadir Turgut , Fahri Ovalı %T Comparison of Risk Factors and Neonatal Outcomes in Early-Onset and Late-Onset Preeclampsia %D 2020 %J Çocuk Dergisi %P -1308-8491 %V 20 %N 3 %R %U
ISNAD Bulut, Özgül , Hocaoğlu, Meryem , Bulut, Nurgül , Demi̇rer, Selin , Turgut, Abdulkadir , Ovalı, Fahri . "Comparison of Risk Factors and Neonatal Outcomes in Early-Onset and Late-Onset Preeclampsia". Çocuk Dergisi 20 / 3 (Aralık 2020): 100-106 .
AMA Bulut Ö , Hocaoğlu M , Bulut N , Demi̇rer S , Turgut A , Ovalı F . Comparison of Risk Factors and Neonatal Outcomes in Early-Onset and Late-Onset Preeclampsia. Çocuk Dergisi. 2020; 20(3): 100-106.
Vancouver Bulut Ö , Hocaoğlu M , Bulut N , Demi̇rer S , Turgut A , Ovalı F . Comparison of Risk Factors and Neonatal Outcomes in Early-Onset and Late-Onset Preeclampsia. Çocuk Dergisi. 2020; 20(3): 100-106.
IEEE Ö. Bulut , M. Hocaoğlu , N. Bulut , S. Demi̇rer , A. Turgut ve F. Ovalı , "Comparison of Risk Factors and Neonatal Outcomes in Early-Onset and Late-Onset Preeclampsia", Çocuk Dergisi, c. 20, sayı. 3, ss. 100-106, Ara. 2021
Makalenin Yazarları
Özgül BULUT [1]
Meryem HOCAOĞLU [2]
Nurgül BULUT [3]
Selin DEMİRER [4]
Abdulkadir TURGUT [5]
Fahri OVALI [6]
Makale Gönder
Arşiv
Editör Kurulu
İletişim