Investigation of the Relationship Between Chronic Use of Topical Antiglaucomatous Drops and Ocular Demodex Infestation

Öz

AIM : To investigate the relationship between chronic use of topical antiglaucomatous drop and ocular Demodex infestation. MATERIAL AND METHOD: This cross-sectional study included a total of 226 eyes, as both eyes of 55 patients with bilateral glaucoma and 58 control subjects. A total of 8 eyelashes, 2 each from the lower and upper eyelids of all the study participants, were taken and the samples were sent to the parasitology laboratory for analysis. RESULTS: The mean age of the study participants was 66.48±15.19 years in the glaucoma patients, and 64.76±10.89 years in the control group. From analysis of the eyelash samples taken, ocular Demodex was positive in 55% of patients with glaucoma, and negative in 45%. In the control group, Demodex was positive in 34% and negative in 66%. Demodex infestation positivity was determined to be statistically significantly higher in patients with glaucoma (p= 0.042). CONCLUSION: The rate of ocular Demodex infestation increases with age, and it is estimated that this rate is further increased by the use of chronic topical antiglaucomatous drops.

Anahtar Kelimeler

• Antiglaucomatous Drops
• Demodex Folliculorum
• Glaucoma
• Ocular Demodex

Topikal Antiglokomatöz Damlaların Kronik Kullanımı İle Oküler Demodeks Enfestasyonu Arasındaki İlişkinin Araştırılması

Öz

AMAÇ : Topikal antiglokomatöz damlaların kronik kullanımı ile oküler Demodeks infestasyonu arasındaki ilişkiyi araştırmak. GEREÇ VE YÖNTEM: Bu kesitsel çalışmaya 55 bilateral glokomlu hasta ve 58 kontrol olgusunun her iki gözü olmak üzere toplam 226 göz dahil edildi. Tüm katılımcılardan alt ve üst göz kapaklarından 2'şer adet olmak üzere toplam 8 adet kirpik alındı ve örnekler analiz için parazitoloji laboratuvarına gönderildi. BULGULAR: Çalışmaya katılanların yaş ortalaması glokom hastalarında 66,48±15,19, kontrol grubunda 64,76±10,89 idi. Alınan kirpik örneklerinin analizinden, oküler Demodeks glokomlu hastaların %55'inde pozitif ve %45'inde negatifti. Kontrol grubunda Demodeks %34 pozitif, %66 negatifti. Demodeks enfestasyon pozitifliği glokomlu hastalarda istatistiksel olarak anlamlı derecede yüksek saptandı (p= 0,042). SONUÇ: Oküler Demodeks infestasyon oranı yaşla birlikte artmaktadır ve kronik topikal antiglokomatöz damla kullanımı ile bu oranın daha da arttığı tahmin edilmektedir.

Anahtar Kelimeler

• Antiglaucomatous Drops
• Demodex Folliculorum
• Glaucoma
• Ocular Demodex

Kaynakça

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