CYTOTOXIC ACTIVITY OF PLATINUM(II) AND PLATINUM(IV) COMPLEXES BEARING 5(6)-NON/CHLOROSUBSTITUTED-2- HYDROXYMETHYL BENZIMIDAZOLE LIGANDS AGAINST HEp-2 CELL LINE :

Semra Utku

doi:10.1501/Eczfak_0000000074

TR EN

5(6)-NON/KLOROSUBSTİTÜE-2-HİDROKSİMETİLBENZİMİDAZOL LİGANDI TAŞIYAN PLATİN(II) VE PLATİN(IV) KOMPLEKSLERİNİN HEp-2 HÜCRELERİNE KARŞI SİTOTOKSİK AKTİVİTESİ

Öz

Yapıları sırasıyla [PtL2Cl2], [PtL2I2] ve [PtL2Cl4], [PtL2Cl2(OH)2] (L= 5(6)-non/kloro-substitüe-2hidroksimetilbenzimidazol “taşıyıcı ligand”) olan dört platin(II) ve dört platin(IV) kompleksi in vitro sitotoksik aktivitleri Hücre Kültür Metodu kullanılarak insan HEp-2 (larinks kanseri) hücre hattında test edildi. Genel olarak insan HEp-2 hücre hattına karşı, karboplatinden daha aktif bulunan kompleksler sisplatin ile karşılaştırılabilir sitotoksik etki gösterdi

Anahtar Kelimeler

Benzimidazol, Sitotoksik aktivite, HEp-2 hücre hattı, Platin(II) kompleksi, Platin(IV) kompleksi

Ayrıntılar

Birincil Dil

İngilizce

Konular

-

Bölüm

-

Yazarlar

Semra Utku Bu kişi benim

Yayımlanma Tarihi

1 Mart 2007

Gönderilme Tarihi

1 Mart 2007

Kabul Tarihi

-

Yayımlandığı Sayı

Yıl 2007 Cilt: 36 Sayı: 1

DOI

https://doi.org/10.1501/Eczfak_0000000074

IZ

https://izlik.org/JA93ZC28ER

Kaynak Göster

RIS / Bibtex

APA

Utku, S. (2007). CYTOTOXIC ACTIVITY OF PLATINUM(II) AND PLATINUM(IV) COMPLEXES BEARING 5(6)-NON/CHLOROSUBSTITUTED-2- HYDROXYMETHYL BENZIMIDAZOLE LIGANDS AGAINST HEp-2 CELL LINE : Journal of Faculty of Pharmacy of Ankara University, 36(1), 21-30. https://doi.org/10.1501/Eczfak_0000000074

AMA

1.Utku S. CYTOTOXIC ACTIVITY OF PLATINUM(II) AND PLATINUM(IV) COMPLEXES BEARING 5(6)-NON/CHLOROSUBSTITUTED-2- HYDROXYMETHYL BENZIMIDAZOLE LIGANDS AGAINST HEp-2 CELL LINE : Ankara Ecz. Fak. Derg. 2007;36(1):21-30. doi:10.1501/Eczfak_0000000074

Chicago

Utku, Semra. 2007. “CYTOTOXIC ACTIVITY OF PLATINUM(II) AND PLATINUM(IV) COMPLEXES BEARING 5(6)-NON/CHLOROSUBSTITUTED-2- HYDROXYMETHYL BENZIMIDAZOLE LIGANDS AGAINST HEp-2 CELL LINE :”. Journal of Faculty of Pharmacy of Ankara University 36 (1): 21-30. https://doi.org/10.1501/Eczfak_0000000074.

EndNote

Utku S (01 Mart 2007) CYTOTOXIC ACTIVITY OF PLATINUM(II) AND PLATINUM(IV) COMPLEXES BEARING 5(6)-NON/CHLOROSUBSTITUTED-2- HYDROXYMETHYL BENZIMIDAZOLE LIGANDS AGAINST HEp-2 CELL LINE : Journal of Faculty of Pharmacy of Ankara University 36 1 21–30.

IEEE

[1]S. Utku, “CYTOTOXIC ACTIVITY OF PLATINUM(II) AND PLATINUM(IV) COMPLEXES BEARING 5(6)-NON/CHLOROSUBSTITUTED-2- HYDROXYMETHYL BENZIMIDAZOLE LIGANDS AGAINST HEp-2 CELL LINE :”, Ankara Ecz. Fak. Derg., c. 36, sy 1, ss. 21–30, Mar. 2007, doi: 10.1501/Eczfak_0000000074.

ISNAD

Utku, Semra. “CYTOTOXIC ACTIVITY OF PLATINUM(II) AND PLATINUM(IV) COMPLEXES BEARING 5(6)-NON/CHLOROSUBSTITUTED-2- HYDROXYMETHYL BENZIMIDAZOLE LIGANDS AGAINST HEp-2 CELL LINE :”. Journal of Faculty of Pharmacy of Ankara University 36/1 (01 Mart 2007): 21-30. https://doi.org/10.1501/Eczfak_0000000074.

JAMA

1.Utku S. CYTOTOXIC ACTIVITY OF PLATINUM(II) AND PLATINUM(IV) COMPLEXES BEARING 5(6)-NON/CHLOROSUBSTITUTED-2- HYDROXYMETHYL BENZIMIDAZOLE LIGANDS AGAINST HEp-2 CELL LINE : Ankara Ecz. Fak. Derg. 2007;36:21–30.

MLA

Utku, Semra. “CYTOTOXIC ACTIVITY OF PLATINUM(II) AND PLATINUM(IV) COMPLEXES BEARING 5(6)-NON/CHLOROSUBSTITUTED-2- HYDROXYMETHYL BENZIMIDAZOLE LIGANDS AGAINST HEp-2 CELL LINE :”. Journal of Faculty of Pharmacy of Ankara University, c. 36, sy 1, Mart 2007, ss. 21-30, doi:10.1501/Eczfak_0000000074.

Vancouver

1.Semra Utku. CYTOTOXIC ACTIVITY OF PLATINUM(II) AND PLATINUM(IV) COMPLEXES BEARING 5(6)-NON/CHLOROSUBSTITUTED-2- HYDROXYMETHYL BENZIMIDAZOLE LIGANDS AGAINST HEp-2 CELL LINE : Ankara Ecz. Fak. Derg. 01 Mart 2007;36(1):21-30. doi:10.1501/Eczfak_0000000074