Yıl 2020, Cilt 44 , Sayı 1, Sayfalar 61 - 69 2020-01-31

CHEMICAL CHARACTERIZATION OF THE FATTY ACID COMPOSITIONS AND ANTMICROBIAL ACTIVITY OF SUMAC (RHUS CORIARIA L.) FRUITS, GROWING NATURALLY IN TURKEY AND SOLD IN HERBALIST MARKETS
TÜRKİYE'DE DOĞAL OLARAK YETİŞEN VE AKTARLARDA SATILAN SUMAK (RHUS CORIARIA L.) MEYVELERİNİN YAĞ ASİDİ KOMPOZİSYONLARININ KİMYASAL KARAKTERİZASYONU VE ANTİMİKROBİYAL AKTİVİTESİ

Gülderen YILMAZ [1] , Gulnur EKŞİ [2] , Betül DEMİRCİ [3] , Fatih DEMİRCİ [4]


ABSTRACT

Objective: The aim of this study was to compare the fatty acid components and antimicrobial properties of R. coriaria L. samples which were sold as powder and grains tjat show natural distribution in Tunceli and Siirt.

 Material and Method: After the seeds were weighed and powdered, fixed oils were obtained by using soxhalet apparatus. Obtained fixed oils were analyzed by GC and GC / MS methods after methylation process. In vitro antimicrobial activity studies of the samples were performed using six different Gram negative and Gram positive bacteria and Candida albicans using EUCAST disc diffusion and CLSI microdilution methods.

Results and Discussion: The main fatty acid components of all samples were determined as oleic acid (42.2 - 43.3%), linoleic acid (25.2 - 28.5%) and palmitic acid (18.4-221.5%), respectively. In vitro antimicrobial activity of fixed oils, such as Escherichia coli NRRL B-3008, Staphylococcus aureus ATCC 6538, S. epidermidis ATCC 14990, Pseudomonas aeruginosa ATCC 27853, Bacillus subtilis NRRL B-A78 A78 Ausugusar ATC 27853. Results were compared with standard antimicrobial agents and MIC values> 2.5 - 0.22 mg / mL. The results were found to be significant in terms of antimicrobial efficacy.

Amaç: Bu çalışma Tunceli ve Siirt ilerinde doğal olarak yayılış gösteren örnekler ile aktarlarda toz ve tane olarak satılan R. coriaria L. örneklerinin yağ asiti bileşenleri ve antimikrobiyal özelliklerini karşılaştırmak amacı ile yapılmıştır.

Gereç ve Yöntem: Tohumlar tartıldıktan ve toz haline getirildikten sonra soksalet kullanarak sabit yağları elde edilmiştir. Elde edilen sabit yağların, metilleme işlemi yapıldıktan sonra, GC ve GC/MS yöntemleriyle eş zamanlı olarak analizleri gerçekleştirilmiştir. Sabit yağ numunelerinin in vitro antimikrobiyal aktivite çalışmaları altı farklı Gram negatif ve Gram pozitif bakteri ve Candida albicans’a karşı EUCAST disk difüzyon ve CLSI mikrodilüsyon yöntemleri kullanılarak gerçekleştirilmiştir.

Sonuç ve Tartışma: Tüm numunelerin ana yağ asidi bileşenleri, sırasıyla oleik asit (%42.2 - 43.3), linoleik asit (%25.2 - 28.5) ve palmitik asit (%18.4-221.5) olarak tanımlandı. Sabit yağların in vitro antimikrobiyal aktivitesi, Escherichia coli NRRL B-3008, Staphylococcus aureus ATCC 6538, S. epidermidis ATCC 14990, Pseudomonas aeruginosa ATCC 27853, Bacillus subtilis NRRL B-A78 A78 gibi insan patojenik mikroorganizmalarına karşı gerçekleştirildi. Sonuçlar standart antimikrobiyal maddeler ile karşılaştırılmış ve MIC değerleri > 2,5 - 0.22 mg/ml belirlenmiştir. Sonuçların antimikrobiyal etkinlik açından kayda değer olduğu görülmüştür.

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Birincil Dil en
Konular Farmakoloji ve Eczacılık
Bölüm Araştırma Makalesi
Yazarlar

Orcid: 0000-0002-6569-4766
Yazar: Gülderen YILMAZ (Sorumlu Yazar)
Kurum: Ankara University faculty of Pharmacy
Ülke: Turkey


Orcid: 0000-0002-6869-8703
Yazar: Gulnur EKŞİ
Kurum: ANKARA UNIVERSITY
Ülke: Turkey


Orcid: 0000-0003-2343-746X
Yazar: Betül DEMİRCİ
Kurum: ANADOLU UNIVERSITY
Ülke: Turkey


Orcid: 0000-0003-1497-3017
Yazar: Fatih DEMİRCİ
Kurum: ANADOLU UNIVERSITY
Ülke: Turkey


Tarihler

Yayımlanma Tarihi : 31 Ocak 2020

Bibtex @araştırma makalesi { jfpanu645467, journal = {Journal of Faculty of Pharmacy of Ankara University}, issn = {1015-3918}, eissn = {2564-6524}, address = {Ankara University Faculty of Pharmacy Degol Str. TR-06100 Tandogan/Ankra/TURKEY}, publisher = {Ankara Üniversitesi}, year = {2020}, volume = {44}, pages = {61 - 69}, doi = {10.33483/jfpau.645467}, title = {CHEMICAL CHARACTERIZATION OF THE FATTY ACID COMPOSITIONS AND ANTMICROBIAL ACTIVITY OF SUMAC (RHUS CORIARIA L.) FRUITS, GROWING NATURALLY IN TURKEY AND SOLD IN HERBALIST MARKETS}, key = {cite}, author = {YILMAZ, Gülderen and EKŞİ, Gulnur and DEMİRCİ, Betül and DEMİRCİ, Fatih} }
APA YILMAZ, G , EKŞİ, G , DEMİRCİ, B , DEMİRCİ, F . (2020). CHEMICAL CHARACTERIZATION OF THE FATTY ACID COMPOSITIONS AND ANTMICROBIAL ACTIVITY OF SUMAC (RHUS CORIARIA L.) FRUITS, GROWING NATURALLY IN TURKEY AND SOLD IN HERBALIST MARKETS. Journal of Faculty of Pharmacy of Ankara University , 44 (1) , 61-69 . DOI: 10.33483/jfpau.645467
MLA YILMAZ, G , EKŞİ, G , DEMİRCİ, B , DEMİRCİ, F . "CHEMICAL CHARACTERIZATION OF THE FATTY ACID COMPOSITIONS AND ANTMICROBIAL ACTIVITY OF SUMAC (RHUS CORIARIA L.) FRUITS, GROWING NATURALLY IN TURKEY AND SOLD IN HERBALIST MARKETS". Journal of Faculty of Pharmacy of Ankara University 44 (2020 ): 61-69 <https://dergipark.org.tr/tr/pub/jfpanu/issue/52196/645467>
Chicago YILMAZ, G , EKŞİ, G , DEMİRCİ, B , DEMİRCİ, F . "CHEMICAL CHARACTERIZATION OF THE FATTY ACID COMPOSITIONS AND ANTMICROBIAL ACTIVITY OF SUMAC (RHUS CORIARIA L.) FRUITS, GROWING NATURALLY IN TURKEY AND SOLD IN HERBALIST MARKETS". Journal of Faculty of Pharmacy of Ankara University 44 (2020 ): 61-69
RIS TY - JOUR T1 - CHEMICAL CHARACTERIZATION OF THE FATTY ACID COMPOSITIONS AND ANTMICROBIAL ACTIVITY OF SUMAC (RHUS CORIARIA L.) FRUITS, GROWING NATURALLY IN TURKEY AND SOLD IN HERBALIST MARKETS AU - Gülderen YILMAZ , Gulnur EKŞİ , Betül DEMİRCİ , Fatih DEMİRCİ Y1 - 2020 PY - 2020 N1 - doi: 10.33483/jfpau.645467 DO - 10.33483/jfpau.645467 T2 - Journal of Faculty of Pharmacy of Ankara University JF - Journal JO - JOR SP - 61 EP - 69 VL - 44 IS - 1 SN - 1015-3918-2564-6524 M3 - doi: 10.33483/jfpau.645467 UR - https://doi.org/10.33483/jfpau.645467 Y2 - 2019 ER -
EndNote %0 Ankara Üniversitesi Eczacılık Fakültesi Dergisi CHEMICAL CHARACTERIZATION OF THE FATTY ACID COMPOSITIONS AND ANTMICROBIAL ACTIVITY OF SUMAC (RHUS CORIARIA L.) FRUITS, GROWING NATURALLY IN TURKEY AND SOLD IN HERBALIST MARKETS %A Gülderen YILMAZ , Gulnur EKŞİ , Betül DEMİRCİ , Fatih DEMİRCİ %T CHEMICAL CHARACTERIZATION OF THE FATTY ACID COMPOSITIONS AND ANTMICROBIAL ACTIVITY OF SUMAC (RHUS CORIARIA L.) FRUITS, GROWING NATURALLY IN TURKEY AND SOLD IN HERBALIST MARKETS %D 2020 %J Journal of Faculty of Pharmacy of Ankara University %P 1015-3918-2564-6524 %V 44 %N 1 %R doi: 10.33483/jfpau.645467 %U 10.33483/jfpau.645467
ISNAD YILMAZ, Gülderen , EKŞİ, Gulnur , DEMİRCİ, Betül , DEMİRCİ, Fatih . "CHEMICAL CHARACTERIZATION OF THE FATTY ACID COMPOSITIONS AND ANTMICROBIAL ACTIVITY OF SUMAC (RHUS CORIARIA L.) FRUITS, GROWING NATURALLY IN TURKEY AND SOLD IN HERBALIST MARKETS". Journal of Faculty of Pharmacy of Ankara University 44 / 1 (Ocak 2020): 61-69 . https://doi.org/10.33483/jfpau.645467
AMA YILMAZ G , EKŞİ G , DEMİRCİ B , DEMİRCİ F . CHEMICAL CHARACTERIZATION OF THE FATTY ACID COMPOSITIONS AND ANTMICROBIAL ACTIVITY OF SUMAC (RHUS CORIARIA L.) FRUITS, GROWING NATURALLY IN TURKEY AND SOLD IN HERBALIST MARKETS. Ankara Ecz. Fak. Derg.. 2020; 44(1): 61-69.
Vancouver YILMAZ G , EKŞİ G , DEMİRCİ B , DEMİRCİ F . CHEMICAL CHARACTERIZATION OF THE FATTY ACID COMPOSITIONS AND ANTMICROBIAL ACTIVITY OF SUMAC (RHUS CORIARIA L.) FRUITS, GROWING NATURALLY IN TURKEY AND SOLD IN HERBALIST MARKETS. Journal of Faculty of Pharmacy of Ankara University. 2020; 44(1): 69-61.